A Phase II study of the polyamine analog N1,N11-diethylnorspermine (DENSpm) daily for five days every 21 days in patients with previously treated metastatic breast cancer.
about
Polyamines and cancer: implications for chemotherapy and chemopreventionHerbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity.Novel Pt(II) and Pd(II) complexes with polyamine analogues: synthesis and vibrational analysis.Spermine oxidase (SMO) activity in breast tumor tissues and biochemical analysis of the anticancer spermine analogues BENSpm and CPENSpm.The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell linesCharacterization of Pt-, Pd-spermine complexes for their effect on polyamine pathway and cisplatin resistance in A2780 ovarian carcinoma cells.Combination effects of platinum drugs and N1, N11 diethylnorspermine on spermidine/spermine N1-acetyltransferase, polyamines and growth inhibition in A2780 human ovarian carcinoma cells and their oxaliplatin and cisplatin-resistant variantsA novel assay platform for the detection of translation modulators of spermidine/spermine acetyltransferaseSynergistic apoptosis of MCF-7 breast cancer cells by 2-methoxyestradiol and bis(ethyl)norspermineIn vitro and in vivo effects of the conformationally restricted polyamine analogue CGC-11047 on small cell and non-small cell lung cancer cells.Histone deacetylase inhibition overcomes drug resistance through a miRNA-dependent mechanism.Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responsesRecent advances in the development of polyamine analogues as antitumor agents.Increased breast cancer cell toxicity by palladination of the polyamine analogue N (1),N (11)-bis(ethyl)norspermine.Targeting polyamine metabolism for cancer therapy and prevention.Mechanistic studies of mouse polyamine oxidase with N1,N12-bisethylspermine as a substratePolyamines and Their Role in Virus Infection.Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma.Antizyme induction mediates feedback limitation of the incorporation of specific polyamine analogues in tissue culture.Polyamine analogues: potent inducers of nucleosomal array oligomerization and inhibitors of yeast cell growth.Oil for the cancer engine: The cross-talk between oncogenic signaling and polyamine metabolism.Cellular and Animal Model Studies on the Growth Inhibitory Effects of Polyamine Analogues on Breast Cancer.
P2860
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P2860
A Phase II study of the polyamine analog N1,N11-diethylnorspermine (DENSpm) daily for five days every 21 days in patients with previously treated metastatic breast cancer.
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
A Phase II study of the polyam ...... ated metastatic breast cancer.
@ast
A Phase II study of the polyam ...... ated metastatic breast cancer.
@en
type
label
A Phase II study of the polyam ...... ated metastatic breast cancer.
@ast
A Phase II study of the polyam ...... ated metastatic breast cancer.
@en
prefLabel
A Phase II study of the polyam ...... ated metastatic breast cancer.
@ast
A Phase II study of the polyam ...... ated metastatic breast cancer.
@en
P2093
P1476
A Phase II study of the polyam ...... eated metastatic breast cancer
@en
P2093
Antonio C Wolff
Carol D Riley
Deborah K Armstrong
John F Bender
John H Fetting
M Katherine Carducci
Nancy E Davidson
Robert A Casero
P304
P407
P433
P577
2003-12-01T00:00:00Z