Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma.
about
Novel interaction of ornithine decarboxylase with sepiapterin reductase regulates neuroblastoma cell proliferation.Polyamine analog TBP inhibits proliferation of human K562 chronic myelogenous leukemia cells by induced apoptosis.A Phase I Trial of DFMO Targeting Polyamine Addiction in Patients with Relapsed/Refractory NeuroblastomaDiscovery of novel inhibitors of human S-adenosylmethionine decarboxylase based on in silico high-throughput screening and a non-radioactive enzymatic assay.Molecular profiling of childhood cancer: Biomarkers and novel therapiesTargeting RNA polymerase I to treat MYC-driven cancer.Self-immolative polycations as gene delivery vectors and prodrugs targeting polyamine metabolism in cancer.AMXT-1501, a novel polyamine transport inhibitor, synergizes with DFMO in inhibiting neuroblastoma cell proliferation by targeting both ornithine decarboxylase and polyamine transport.Editorial: Targeting MYCN in Pediatric Cancers.Oil for the cancer engine: The cross-talk between oncogenic signaling and polyamine metabolism.Alpha-Difluoromethylornithine, an Irreversible Inhibitor of Polyamine Biosynthesis, as a Therapeutic Strategy against Hyperproliferative and Infectious Diseases.MYCN drives glutaminolysis in neuroblastoma and confers sensitivity to an ROS augmenting agent.Myc, Oncogenic Protein Translation, and the Role of Polyamines.Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance.
P2860
Q33578405-FBF171B0-12F2-4C86-9055-B714DB2C962AQ34582662-5A1C010F-E64E-47FF-A8EA-2CFC55998180Q35644191-84625275-A33E-4F31-8AE2-B82D362830C0Q35648294-A99A5142-4791-41E5-8C64-40317DDE7687Q36250783-2D67BBE4-25BD-4BA5-A561-74F28C2C0FA5Q38194418-A9921267-9A2F-4DAC-884E-9520BF783A47Q38963161-6326E78D-09C6-4E0F-AE5B-4A8BF88858CFQ39185908-60568C4D-0D21-4DFD-960A-61A4EEFC9017Q40606235-21CE46F3-3C01-4239-90B9-2CE7DF6CBE05Q48154027-4D90CBC7-185C-4A25-AA56-E496164E395CQ48506495-65D96037-4639-4B93-9421-000471A6F5C2Q52694952-811C08FC-D73E-4D1E-94B4-BF1DEF6468DEQ55414287-F7A7E70E-5CF3-434B-8192-96D6081C48BAQ55692299-AA66387C-142D-4625-BCAC-BB2EB4685E8F
P2860
Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma.
@en
type
label
Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma.
@en
prefLabel
Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma.
@en
P2093
P2860
P356
P1476
Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma
@en
P2093
David S Ziegler
Glenn Marshall
Laura D Gamble
Michael D Hogarty
Murray D Norris
Xueyuan Liu
P2860
P356
10.3389/FONC.2012.00162
P50
P577
2012-11-16T00:00:00Z