Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura.
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Binding of ADAMTS13 to von Willebrand factorMultiple domains of ADAMTS13 are targeted by autoantibodies against ADAMTS13 in patients with acquired idiopathic thrombotic thrombocytopenic purpuraVon Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpuraCurrent concepts in thrombotic thrombocytopenic purpuraPathogenesis of thrombotic microangiopathiesProteolytic processing of von Willebrand factor by adamts13 and leukocyte proteasesCleavage of ultra-large von Willebrand factor by ADAMTS-13 under flow conditionsThe von Willebrand factor-cleaving protease (ADAMTS-13) and the diagnosis of thrombotic thrombocytopenic purpura (TTP)The ADAMTS metalloproteinasesAttack of the acronyms: TTP, VWF, ADAMTS-13 and SELDI-TOF-MS.Thrombotic thrombocytopenic purpura and its diagnosis.Enzymatically active ADAMTS13 variants are not inhibited by anti-ADAMTS13 autoantibodies: a novel therapeutic strategy?Prognostic value of inhibitory anti-ADAMTS13 antibodies in adult-acquired thrombotic thrombocytopenic purpura.Molecular biology of ADAMTS13 and diagnostic utility of ADAMTS13 proteolytic activity and inhibitor assays.Systemic antithrombotic effects of ADAMTS13.ADAMTS-13 plasma level determination uncovers antigen absence in acquired thrombotic thrombocytopenic purpura and ethnic differences.Inhibitory autoantibodies against ADAMTS-13 in patients with thrombotic thrombocytopenic purpura bind ADAMTS-13 protease and may accelerate its clearance in vivo.ADAMTS13 and microvascular thrombosisThrombotic thrombocytopenic purpura: a thrombotic disorder caused by ADAMTS13 deficiencyThe kidney in thrombotic thrombocytopenic purpura.Advantages and limits of ADAMTS13 testing in thrombotic thrombocytopenic purpura.An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWFThrombotic microangiopathies: multimers, metalloprotease, and beyond.Humoral immune response to ADAMTS13 in acquired thrombotic thrombocytopenic purpura.Stroke in a young patient treated by alteplase heralding an acquired thrombotic thrombocytopenic purpura.Residues Arg568 and Phe592 contribute to an antigenic surface for anti-ADAMTS13 antibodies in the spacer domainNovel recombinant glycosylphosphatidylinositol (GPI)-anchored ADAMTS13 and variants for assessment of anti-ADAMTS13 autoantibodies in patients with thrombotic thrombocytopenic purpura.Evidence for a role of anti-ADAMTS13 autoantibodies despite normal ADAMTS13 activity in recurrent thrombotic thrombocytopenic purpura.Seasonal association of thrombotic thrombocytopenic purpura.Gain-of-function ADAMTS13 variants that are resistant to autoantibodies against ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura.Development and validation of a predictive model for death in acquired severe ADAMTS13 deficiency-associated idiopathic thrombotic thrombocytopenic purpura: the French TMA Reference Center experience.Presence of anti-ADAMTS13 antibodies in obesity.Safety and efficacy of cryoprecipitate-poor plasma as a replacement fluid for therapeutic plasma exchange in thrombotic thrombocytopenic purpura: a single center retrospective evaluation.Class II human leucocyte antigen DRB1*11 in hairy cell leukaemia patients with and without haemolytic uraemic syndrome.A novel flow-based assay reveals discrepancies in ADAMTS-13 inhibitor assessment as compared with a conventional clinical static assay.Conformational activation of ADAMTS13.Platelet-delivered ADAMTS13 inhibits arterial thrombosis and prevents thrombotic thrombocytopenic purpura in murine models.ADAMTS13 and von Willebrand factor interactions.High-resolution epitope mapping by HX MS reveals the pathogenic mechanism and a possible therapy for autoimmune TTP syndrome.Pathogenicity of Anti-ADAMTS13 Autoantibodies in Acquired Thrombotic Thrombocytopenic Purpura.
P2860
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P2860
Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura.
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Epitope mapping of ADAMTS13 au ...... otic thrombocytopenic purpura.
@ast
Epitope mapping of ADAMTS13 au ...... otic thrombocytopenic purpura.
@en
type
label
Epitope mapping of ADAMTS13 au ...... otic thrombocytopenic purpura.
@ast
Epitope mapping of ADAMTS13 au ...... otic thrombocytopenic purpura.
@en
prefLabel
Epitope mapping of ADAMTS13 au ...... otic thrombocytopenic purpura.
@ast
Epitope mapping of ADAMTS13 au ...... otic thrombocytopenic purpura.
@en
P2093
P50
P1433
P1476
Epitope mapping of ADAMTS13 au ...... otic thrombocytopenic purpura.
@en
P2093
Christoph Klaus
Friedrich Dorner
Friedrich Scheiflinger
Jan-Dirk Studt
P304
P356
10.1182/BLOOD-2003-12-4165
P407
P577
2004-02-19T00:00:00Z