Residues Arg568 and Phe592 contribute to an antigenic surface for anti-ADAMTS13 antibodies in the spacer domain
about
Disappearing acts of ADAMTS13ADAMTS13 and von Willebrand factor in thrombotic thrombocytopenic purpuraEssential domains of a disintegrin and metalloprotease with thrombospondin type 1 repeats-13 metalloprotease required for modulation of arterial thrombosis.Gain-of-function ADAMTS13 variants that are resistant to autoantibodies against ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura.Antigen and substrate withdrawal in the management of autoimmune thrombotic disorders.Persistence of circulating ADAMTS13-specific immune complexes in patients with acquired thrombotic thrombocytopenic purpura.A novel flow-based assay reveals discrepancies in ADAMTS-13 inhibitor assessment as compared with a conventional clinical static assay.Platelet-delivered ADAMTS13 inhibits arterial thrombosis and prevents thrombotic thrombocytopenic purpura in murine models.ADAMTS13 and von Willebrand factor interactions.High-resolution epitope mapping by HX MS reveals the pathogenic mechanism and a possible therapy for autoimmune TTP syndrome.Pathogenicity of Anti-ADAMTS13 Autoantibodies in Acquired Thrombotic Thrombocytopenic Purpura.ADAMTS13 and anti-ADAMTS13 autoantibodies in thrombotic thrombocytopenic purpura - current perspectives and new treatment strategies.ADAMTS13 autoantibodies cloned from patients with acquired thrombotic thrombocytopenic purpura: 1. Structural and functional characterization in vitroIdiopathic thrombotic thrombocytopenic purpura: strongest risk factor for relapse from remission is having had a relapse.Structure-function and regulation of ADAMTS-13 protease.ADAMTS13, TTP and BeyondAnti-ADAMTS13 IgG autoantibodies present in healthy individuals share linear epitopes with those in patients with thrombotic thrombocytopenic purpura.Dissecting the pathophysiology of immune thrombotic thrombocytopenic purpura: interplay between genes and environmental triggers.Thrombotic thrombocytopenic purpura
P2860
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P2860
Residues Arg568 and Phe592 contribute to an antigenic surface for anti-ADAMTS13 antibodies in the spacer domain
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Residues Arg568 and Phe592 con ...... ntibodies in the spacer domain
@ast
Residues Arg568 and Phe592 con ...... ntibodies in the spacer domain
@en
type
label
Residues Arg568 and Phe592 con ...... ntibodies in the spacer domain
@ast
Residues Arg568 and Phe592 con ...... ntibodies in the spacer domain
@en
prefLabel
Residues Arg568 and Phe592 con ...... ntibodies in the spacer domain
@ast
Residues Arg568 and Phe592 con ...... ntibodies in the spacer domain
@en
P2093
P2860
P1433
P1476
Residues Arg568 and Phe592 con ...... ntibodies in the spacer domain
@en
P2093
Jan Voorberg
Nicoletta Sorvillo
Paul H P Kaijen
Rob Fijnheer
Wouter Pos
P2860
P304
P356
10.3324/HAEMATOL.2010.036327
P577
2011-06-28T00:00:00Z