Insulin/receptor binding: the last piece of the puzzle? What recent progress on the structure of the insulin/receptor complex tells us (or not) about negative cooperativity and activation.
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Higher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain.All-Atom Structural Models of the Transmembrane Domains of Insulin and Type 1 Insulin-Like Growth Factor ReceptorsActivation of transmembrane cell-surface receptors via a common mechanism? The "rotation model".Molecular Dynamics Simulations of Insulin: Elucidating the Conformational Changes that Enable Its BindingElucidating the Activation Mechanism of the Insulin-Family Proteins with Molecular Dynamics Simulations.Achieving high signal-to-noise in cell regulatory systems: Spatial organization of multiprotein transmembrane assemblies of FGFR and MET receptors.The road to the first, fully active and more stable human insulin variant with an additional disulfide bond.Insulin receptor isoforms: an integrated view focused on gestational diabetes mellitus.The neuronal insulin receptor in its environment.Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.Computational study of the activity, dynamics, energetics and conformations of insulin analogues using molecular dynamics simulations: Application to hyperinsulinemia and the critical residue B26.A Comprehensive Survey of the Roles of Highly Disordered Proteins in Type 2 Diabetes.Insulin in motion: The A6-A11 disulfide bond allosterically modulates structural transitions required for insulin activity.Insulin Receptor Isoforms in Physiology and Disease: An Updated View.Visualization of ligand-induced transmembrane signaling in the full-length human insulin receptor.Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis.How ligand binds to the type 1 insulin-like growth factor receptor.Viral insulin-like peptides activate human insulin and IGF-1 receptor signaling: A paradigm shift for host-microbe interactions.Drosophila Insulin-Like Peptides DILP2 and DILP5 Differentially Stimulate Cell Signaling and Glycogen Phosphorylase to Regulate Longevity.Probing the correlation between insulin activity and structural stability through introduction of the rigid A6-A11 bondThe signalling conformation of the insulin receptor ectodomainA versatile insulin analog with high potency for both insulin and insulin-like growth factor 1 receptors: Structural implications for receptor binding
P2860
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P2860
Insulin/receptor binding: the last piece of the puzzle? What recent progress on the structure of the insulin/receptor complex tells us (or not) about negative cooperativity and activation.
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Insulin/receptor binding: the ...... cooperativity and activation.
@ast
Insulin/receptor binding: the ...... cooperativity and activation.
@en
type
label
Insulin/receptor binding: the ...... cooperativity and activation.
@ast
Insulin/receptor binding: the ...... cooperativity and activation.
@en
prefLabel
Insulin/receptor binding: the ...... cooperativity and activation.
@ast
Insulin/receptor binding: the ...... cooperativity and activation.
@en
P2860
P356
P1433
P1476
Insulin/receptor binding: the ...... cooperativity and activation.
@en
P2860
P304
P356
10.1002/BIES.201400190
P407
P577
2015-01-29T00:00:00Z