Role of N-terminal amino acids in the potency of anthrax lethal factor.
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Tumor Targeting and Drug Delivery by Anthrax ToxinAntidotes to anthrax lethal factor intoxication. Part 3: Evaluation of core structures and further modifications to the C2-side chainAnthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasomeAnthrax lethal toxin activates the inflammasome in sensitive rat macrophagesThe heart is an early target of anthrax lethal toxin in mice: a protective role for neuronal nitric oxide synthase (nNOS).Characterization of a Chinese hamster ovary cell mutant having a mutation in elongation factor-2.Susceptibility to anthrax lethal toxin-induced rat death is controlled by a single chromosome 10 locus that includes rNlrp1Inhibition of tumor angiogenesis by the matrix metalloproteinase-activated anthrax lethal toxin in an orthotopic model of anaplastic thyroid carcinoma.Cutting edge: resistance to Bacillus anthracis infection mediated by a lethal toxin sensitive allele of Nalp1b/Nlrp1b.Auranofin protects against anthrax lethal toxin-induced activation of the Nlrp1b inflammasomeKey tissue targets responsible for anthrax-toxin-induced lethality.Efficient targeting of head and neck squamous cell carcinoma by systemic administration of a dual uPA and MMP-activated engineered anthrax toxin.Channel-forming bacterial toxins in biosensing and macromolecule deliveryAllelic variation on murine chromosome 11 modifies host inflammatory responses and resistance to Bacillus anthracisAntidotes to anthrax lethal factor intoxication. Part 1: Discovery of potent lethal factor inhibitors with in vivo efficacy.Recombinant anthrax toxin receptor-Fc fusion proteins produced in plants protect rabbits against inhalational anthrax.MyD88-dependent signaling protects against anthrax lethal toxin-induced impairment of intestinal barrier function.Anthrax toxin targeting of myeloid cells through the CMG2 receptor is essential for establishment of Bacillus anthracis infections in mice.Receptors of anthrax toxin and cell entry.Anthrax edema factor toxicity is strongly mediated by the N-end ruleA Bacillus anthracis strain deleted for six proteases serves as an effective host for production of recombinant proteinsAnthrax and the inflammasomeA d-Amino Acid at the N-Terminus of a Protein Abrogates Its Degradation by the N-End Rule Pathway.Targeting the membrane-anchored serine protease testisin with a novel engineered anthrax toxin prodrug to kill tumor cells and reduce tumor burden.The receptors that mediate the direct lethality of anthrax toxinAnthrax toxin-mediated delivery of the Pseudomonas exotoxin A enzymatic domain to the cytosol of tumor cells via cleavable ubiquitin fusions.Characterization of the native form of anthrax lethal factor for use in the toxin neutralization assay.Solid tumor therapy by selectively targeting stromal endothelial cells.Hijacking multivesicular bodies enables long-term and exosome-mediated long-distance action of anthrax toxin.Cellular and systemic effects of anthrax lethal toxin and edema toxin.Reductive methylation and mutation of an anthrax toxin fusion protein modulates its stability and cytotoxicity.Anthrax Toxin Protective Antigen Variants That Selectively Utilize either the CMG2 or TEM8 Receptors for Cellular Uptake and Tumor Targeting.Anti-tumor activity of anthrax toxin variants that form a functional translocation pore by intermolecular complementation.
P2860
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P2860
Role of N-terminal amino acids in the potency of anthrax lethal factor.
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Role of N-terminal amino acids in the potency of anthrax lethal factor.
@ast
Role of N-terminal amino acids in the potency of anthrax lethal factor.
@en
type
label
Role of N-terminal amino acids in the potency of anthrax lethal factor.
@ast
Role of N-terminal amino acids in the potency of anthrax lethal factor.
@en
prefLabel
Role of N-terminal amino acids in the potency of anthrax lethal factor.
@ast
Role of N-terminal amino acids in the potency of anthrax lethal factor.
@en
P2093
P2860
P1433
P1476
Role of N-terminal amino acids in the potency of anthrax lethal factor.
@en
P2093
Devorah Crown
Pradeep K Gupta
Rasem J Fattah
P2860
P356
10.1371/JOURNAL.PONE.0003130
P407
P577
2008-09-03T00:00:00Z