Translational mini-review series on complement factor H: genetics and disease associations of human complement factor H.
about
Structural analysis of the C-terminal region (modules 18-20) of complement regulator factor H (FH)Atypical hemolytic uremic syndromeStructural basis for engagement by complement factor H of C3b on a self surfaceIdentification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritisThe central portion of factor H (modules 10-15) is compact and contains a structurally deviant CCP moduleStructure of complement fragment C3b-factor H and implications for host protection by complement regulatorsAdvances and challenges in the management of complement-mediated thrombotic microangiopathiesPrinciples of separation: indications and therapeutic targets for plasma exchange.Therapeutic regulation of complement in patients with renal disease - where is the promise?The complotype: dictating risk for inflammation and infectionSolution Structure of CCP Modules 10–12 Illuminates Functional Architecture of the Complement Regulator, Factor HStructural Basis for Complement Evasion by Lyme Disease Pathogen Borrelia burgdorferiProperdin: a tightly regulated critical inflammatory modulatorFrom Normal Skin to Squamous Cell Carcinoma: A Quest for Novel BiomarkersComplement regulator CD46: genetic variants and disease associationsComplement Evasion Mediated by Enhancement of Captured Factor H: Implications for Protection of Self-Surfaces from ComplementThe development of atypical hemolytic uremic syndrome depends on complement C5Staphylococcus aureus surface protein SdrE binds complement regulator factor H as an immune evasion tacticHaemolytic uraemic syndrome.Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritisGenetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degenerationTranslational mini-review series on complement factor H: renal diseases associated with complement factor H: novel insights from humans and animals.Complement and the atypical hemolytic uremic syndrome in children.Complement factor H: using atomic resolution structure to illuminate disease mechanisms.Lack of association between polymorphisms in C4b-binding protein and atypical haemolytic uraemic syndrome in the Spanish population.Successful renal transplantation in factor H autoantibody associated HUS with CFHR1 and 3 deficiency and CFH variant G2850T.Disease-associated N-terminal complement factor H mutations perturb cofactor and decay-accelerating activities.Do complement factor H 402Y and C7 M allotypes predispose to (typical) haemolytic uraemic syndrome?Crystallographic determination of the disease-associated T1184R variant of complement regulator factor H.Factor H and CFHR1 polymorphisms associated with atypical Haemolytic Uraemic Syndrome (aHUS) are differently expressed in Tunisian and in Caucasian populations.Common genetic variants in complement genes other than CFH, CD46 and the CFHRs are not associated with aHUS.A prevalent C3 mutation in aHUS patients causes a direct C3 convertase gain of function.Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies.A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degenerationA novel atypical hemolytic uremic syndrome-associated hybrid CFHR1/CFH gene encoding a fusion protein that antagonizes factor H-dependent complement regulation.Complement mutations in diacylglycerol kinase-ε-associated atypical hemolytic uremic syndrome.Factors determining penetrance in familial atypical haemolytic uraemic syndrome.Partial Complement Factor H Deficiency Associates with C3 Glomerulopathy and Thrombotic Microangiopathy.Molecular Basis of Factor H R1210C Association with Ocular and Renal Diseases.Moss-Produced, Glycosylation-Optimized Human Factor H for Therapeutic Application in Complement Disorders.
P2860
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P2860
Translational mini-review series on complement factor H: genetics and disease associations of human complement factor H.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Translational mini-review seri ...... of human complement factor H.
@ast
Translational mini-review seri ...... of human complement factor H.
@en
type
label
Translational mini-review seri ...... of human complement factor H.
@ast
Translational mini-review seri ...... of human complement factor H.
@en
prefLabel
Translational mini-review seri ...... of human complement factor H.
@ast
Translational mini-review seri ...... of human complement factor H.
@en
P2860
P1476
Translational mini-review seri ...... of human complement factor H.
@en
P2093
E Goicoechea de Jorge
S Rodríguez de Córdoba
P2860
P356
10.1111/J.1365-2249.2007.03552.X
P577
2008-01-01T00:00:00Z