about
Immunoglobulin D (IgD)-deficient mice reveal an auxiliary receptor function for IgD in antigen-mediated recruitment of B cellsMice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normallyImmunoglobulin heavy chain gene expression in peripheral blood B lymphocytes.Increased negative selection impairs neonatal B cell repertoire but does not directly lead to generation of disease-associated IgM auto-antibodies.Homeostatic control of B lymphocyte subsets.Analysis of patterns of DNA sequence variation in flanking and coding regions of murine germ-line immunoglobulin heavy-chain variable genes: evolutionary implications.CD21int CD23+ follicular B cells express antigen-specific secretory IgM mRNA as primary and memory responses.Antibody repertoire deep sequencing reveals antigen-independent selection in maturing B cellsB cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals.Severe B cell deficiency and disrupted splenic architecture in transgenic mice expressing the E41K mutated form of Bruton's tyrosine kinase.Altered B cell signalling in autoimmunity.Gene targeting in the Ig kappa locus: efficient generation of lambda chain-expressing B cells, independent of gene rearrangements in Ig kappaEvidence that the V kappa III gene usage is nonstochastic in both adult and newborn peripheral B cells and that peripheral CD5+ adult B cells are oligoclonal.In vivo and in vitro studies of immunoglobulin gene somatic hypermutation.CD4+ T cells and CD40 participate in selection and homeostasis of peripheral B cells.A role for antigen in the maintenance of immunological memory.Dedicator of cytokinesis 8-deficient patients have a breakdown in peripheral B-cell tolerance and defective regulatory T cells.IgBLAST: an immunoglobulin variable domain sequence analysis toolMalignant B cells and antigenic receptor: necessity or habit?Biologic therapies for juvenile arthritisA B-cell receptor-specific selection step governs immature to mature B cell differentiationB cell receptor expression level determines the fate of developing B lymphocytes: receptor editing versus selection.Molecular approaches to the study of human B-cell and (auto)antibody repertoire generation and selection.Expansion, selection and mutation of antigen-specific B cells in germinal centers.Analysis of human monoclonal antibodies elicited by vaccination with a Cryptococcus neoformans glucuronoxylomannan capsular polysaccharide vaccine.Monoclonal immunoglobulin A derived from peritoneal B cells is encoded by both germ line and somatically mutated VH genes and is reactive with commensal bacteriaForced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production.Recruitment of a distinct but related set of VH sequences into the murine CD21hi/CD23- marginal zone B cell repertoire to that seen in the class-switched antibody response.Molecular characterization of J558 genes encoding tight-skin mouse autoantibodies: identical heavy-chain variable genes code for antibodies with different specificities.BAFF/APRIL inhibition decreases selection of naive but not antigen-induced autoreactive B cells in murine systemic lupus erythematosusImmune tolerance to autoantibody-derived peptides delays development of autoimmunity in murine lupus.The transition of pre-BI to pre-BII cells is dependent on the VH structure of the mu/surrogate L chain receptor.Enhancers located in heavy chain regulatory region (hs3a, hs1,2, hs3b, and hs4) are dispensable for diversity of VDJ recombinationStudy of murine B-cell development through analysis of immunoglobulin variable region genes.BLyS-mediated modulation of naive B cell subsets impacts HIV Env-induced antibody responses.Immunoglobulin heavy chain expression shapes the B cell receptor repertoire in human B cell developmentRegulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance.B cells and aging: gauging the interplay of generative, selective, and homeostatic events.Maturation and dispersal of B-cell clones during T cell-dependent antibody responses.Comparison of junctional diversity in the neonatal and adult immunoglobulin repertoires.
P2860
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P2860
description
1991 nî lūn-bûn
@nan
1991 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Most peripheral B cells in mice are ligand selected.
@ast
Most peripheral B cells in mice are ligand selected.
@en
type
label
Most peripheral B cells in mice are ligand selected.
@ast
Most peripheral B cells in mice are ligand selected.
@en
prefLabel
Most peripheral B cells in mice are ligand selected.
@ast
Most peripheral B cells in mice are ligand selected.
@en
P2093
P2860
P356
P1476
Most peripheral B cells in mice are ligand selected.
@en
P2093
P2860
P304
P356
10.1084/JEM.173.6.1357
P407
P577
1991-06-01T00:00:00Z