Enhancers located in heavy chain regulatory region (hs3a, hs1,2, hs3b, and hs4) are dispensable for diversity of VDJ recombination
about
The IgH 3' regulatory region and c-myc-induced B-cell lymphomagenesisElucidation of the enigmatic IgD class-switch recombination via germline deletion of the IgH 3' regulatory region.Eμ and 3'RR IgH enhancers show hierarchic unilateral dependence in mature B-cells.Functional anatomy of the immunoglobulin heavy chain 3΄ super-enhancer needs not only core enhancer elements but also their unique DNA contextTargeting the oncogene B lymphoma deregulator IgH 3' regulatory region does not impede the in vivo inflammatory response in mice.Stage-specific binding profiles of cohesin in resting and activated B lymphocytes suggest a role for cohesin in immunoglobulin class switching and maturation.Developmental Switch in the Transcriptional Activity of a Long-Range Regulatory Element.Deciphering the importance of the palindromic architecture of the immunoglobulin heavy-chain 3' regulatory region.Sequential activation and distinct functions for distal and proximal modules within the IgH 3' regulatory regionTwo Mutually Exclusive Local Chromatin States Drive Efficient V(D)J RecombinationThe IgH 3' regulatory region controls somatic hypermutation in germinal center B cellsEpigenetic Regulation of Individual Modules of the immunoglobulin heavy chain locus 3' Regulatory Region.The IgH 3' regulatory region influences lymphomagenesis in Igλ-Myc miceEfficient role of IgH 3' regulatory region deficient B-cells in the development of oil granulomas.1(st) French-Israeli International Conference on B Cells and therapeutic antibodies: October 23-25, 2011 Jerusalem, Israel.The IgH 3' regulatory region governs μ chain transcription in mature B lymphocytes and the B cell fate.[The IgH 3'RR: Doctor Jekyll and Mister Hyde of B-cell maturation and lymphomagenesis].
P2860
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P2860
Enhancers located in heavy chain regulatory region (hs3a, hs1,2, hs3b, and hs4) are dispensable for diversity of VDJ recombination
description
2012 nî lūn-bûn
@nan
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
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name
Enhancers located in heavy cha ...... diversity of VDJ recombination
@ast
Enhancers located in heavy cha ...... diversity of VDJ recombination
@en
type
label
Enhancers located in heavy cha ...... diversity of VDJ recombination
@ast
Enhancers located in heavy cha ...... diversity of VDJ recombination
@en
prefLabel
Enhancers located in heavy cha ...... diversity of VDJ recombination
@ast
Enhancers located in heavy cha ...... diversity of VDJ recombination
@en
P2093
P2860
P356
P1476
Enhancers located in heavy cha ...... diversity of VDJ recombination
@en
P2093
Christelle Vincent-Fabert
Eric Pinaud
Michel Cogné
Pauline Rouaud
Remi Fiancette
Yves Denizot
P2860
P304
P356
10.1074/JBC.M112.341024
P407
P577
2012-01-23T00:00:00Z