Regulation of platelet myosin light chain (MYL9) by RUNX1: implications for thrombocytopenia and platelet dysfunction in RUNX1 haplodeficiency
about
Mechanism of platelet factor 4 (PF4) deficiency with RUNX1 haplodeficiency: RUNX1 is a transcriptional regulator of PF4.Platelet protein kinase C-theta deficiency with human RUNX1 mutation: PRKCQ is a transcriptional target of RUNX1.Familial myelodysplastic syndromes: a review of the literature.Abrogation of RUNX1 gene expression in de novo myelodysplastic syndrome with t(4;21)(q21;q22).A neonate with congenital amegakaryocytic thrombocytopenia associated with a chromosomal microdeletion at 21q22.11 including the gene RUNX1.Mechanisms underlying platelet function defect in a pedigree with familial platelet disorder with a predisposition to acute myelogenous leukemia: potential role for candidate RUNX1 targets.Two novel RUNX1 mutations in a patient with congenital thrombocytopenia that evolved into a high grade myelodysplastic syndromeHematopoietic transcription factor mutations and inherited platelet dysfunction.Analyses of Genetic and Clinical Parameters for Screening Patients With Inherited Thrombocytopenia with Small or Normal-Sized Platelets.Inherited platelet dysfunction and hematopoietic transcription factor mutations.Dysregulation of PLDN (pallidin) is a mechanism for platelet dense granule deficiency in RUNX1 haplodeficiency.Molecular phenotype and bleeding risks of an inherited platelet disorder in a family with a RUNX1 frameshift mutation.Hematopoietic transcription factor mutations: important players in inherited platelet defects.Defective acid hydrolase secretion in RUNX1 haplodeficiency: Evidence for a global platelet secretory defect.Transcription Factor RUNX1 Regulates Platelet PCTP (Phosphatidylcholine Transfer Protein): Implications for Cardiovascular Events.Identification of vascular and hematopoietic genes downstream of etsrp by deep sequencing in zebrafish.Myxoid liposarcoma-associated EWSR1-DDIT3 selectively represses osteoblastic and chondrocytic transcription in multipotent mesenchymal cells.Genetic sequence analysis of inherited bleeding diseases.Pleiotropic platelet defects in mice with disrupted FOG1-NuRD interactionDeletion of the App-Runx1 region in mice models human partial monosomy 21.Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies.Systems Pharmacogenomics Finds RUNX1 Is an Aspirin-Responsive Transcription Factor Linked to Cardiovascular Disease and Colon Cancer.Myelodysplastic syndromes and acute leukemia with genetic predispositions: a new challenge for hematologists.Myeloid neoplasms with germ line RUNX1 mutation.Gene of the issue: RUNX1 mutations and inherited bleeding.Detection of an Abnormal Myeloid Clone by Flow Cytometry in Familial Platelet Disorder With Propensity to Myeloid Malignancy.RUNX1 regulates genes involved in megakaryocyte differentiation and platelet functionRUNX1:CBFB binds the MYL9 gene promoterMYL9 gene transcription is stimulated by RUNX1:CBFBChallenges on the diagnostic approach of inherited platelet function disorders: Is a paradigm change necessary?
P2860
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P2860
Regulation of platelet myosin light chain (MYL9) by RUNX1: implications for thrombocytopenia and platelet dysfunction in RUNX1 haplodeficiency
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Regulation of platelet myosin ...... ction in RUNX1 haplodeficiency
@ast
Regulation of platelet myosin ...... ction in RUNX1 haplodeficiency
@en
type
label
Regulation of platelet myosin ...... ction in RUNX1 haplodeficiency
@ast
Regulation of platelet myosin ...... ction in RUNX1 haplodeficiency
@en
prefLabel
Regulation of platelet myosin ...... ction in RUNX1 haplodeficiency
@ast
Regulation of platelet myosin ...... ction in RUNX1 haplodeficiency
@en
P2093
P2860
P1433
P1476
Regulation of platelet myosin ...... ction in RUNX1 haplodeficiency
@en
P2093
A Koneti Rao
Danny N Dhanasekaran
Gauthami Jalagadugula
Guangfen Mao
Gurpreet Kaur
Lawrence E Goldfinger
P2860
P304
P356
10.1182/BLOOD-2010-06-289850
P407
P577
2010-09-27T00:00:00Z