Mechanism of platelet factor 4 (PF4) deficiency with RUNX1 haplodeficiency: RUNX1 is a transcriptional regulator of PF4.
about
Regulation of platelet myosin light chain (MYL9) by RUNX1: implications for thrombocytopenia and platelet dysfunction in RUNX1 haplodeficiencyPlatelet protein kinase C-theta deficiency with human RUNX1 mutation: PRKCQ is a transcriptional target of RUNX1.A neonate with congenital amegakaryocytic thrombocytopenia associated with a chromosomal microdeletion at 21q22.11 including the gene RUNX1.RUNX1, but not its familial platelet disorder mutants, synergistically activates PF4 gene expression in combination with ETS family proteins.Hematopoietic transcription factor mutations and inherited platelet dysfunction.Inherited platelet dysfunction and hematopoietic transcription factor mutations.Dysregulation of PLDN (pallidin) is a mechanism for platelet dense granule deficiency in RUNX1 haplodeficiency.Hematopoietic transcription factor mutations: important players in inherited platelet defects.Defective acid hydrolase secretion in RUNX1 haplodeficiency: Evidence for a global platelet secretory defect.Transcription Factor RUNX1 Regulates Platelet PCTP (Phosphatidylcholine Transfer Protein): Implications for Cardiovascular Events.Pleiotropic platelet defects in mice with disrupted FOG1-NuRD interactionSystems Pharmacogenomics Finds RUNX1 Is an Aspirin-Responsive Transcription Factor Linked to Cardiovascular Disease and Colon Cancer.Myelodysplastic syndromes and acute leukemia with genetic predispositions: a new challenge for hematologists.Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity.RUNX1 regulates genes involved in megakaryocyte differentiation and platelet functionHuman NOTCH4 is a key target of RUNX1 in megakaryocytic differentiation.RUNX1:CBFB binds the PF4 gene promoterPF4 gene transcription is stimulated by RUNX1:CBFBChallenges on the diagnostic approach of inherited platelet function disorders: Is a paradigm change necessary?
P2860
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P2860
Mechanism of platelet factor 4 (PF4) deficiency with RUNX1 haplodeficiency: RUNX1 is a transcriptional regulator of PF4.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Mechanism of platelet factor 4 ...... nscriptional regulator of PF4.
@ast
Mechanism of platelet factor 4 ...... nscriptional regulator of PF4.
@en
type
label
Mechanism of platelet factor 4 ...... nscriptional regulator of PF4.
@ast
Mechanism of platelet factor 4 ...... nscriptional regulator of PF4.
@en
prefLabel
Mechanism of platelet factor 4 ...... nscriptional regulator of PF4.
@ast
Mechanism of platelet factor 4 ...... nscriptional regulator of PF4.
@en
P2093
P2860
P1476
Mechanism of platelet factor 4 ...... nscriptional regulator of PF4.
@en
P2093
P2860
P304
P356
10.1111/J.1538-7836.2010.04154.X
P577
2011-02-01T00:00:00Z