Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function.
about
Transcription factors in late megakaryopoiesis and related platelet disordersApoptosis: role in myeloid cell developmentMegakaryopoiesis and platelet production: insight into hematopoietic stem cell proliferation and differentiationBacteria differentially induce degradation of Bcl-xL, a survival protein, by human plateletsAdvances in megakaryocytopoiesis and thrombopoiesis: from bench to bedside.The role of apoptosis in megakaryocytes and platelets.Lessons in platelet production from inherited thrombocytopenias.Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan.Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways.Immune thrombocytopenia: antiplatelet autoantibodies inhibit proplatelet formation by megakaryocytes and impair platelet production in vitroInterspecies Variation in the Functional Consequences of Mutation of Cytochrome cRegulation of platelet lifespan by apoptosis.Agonist-induced platelet procoagulant activity requires shear and a Rac1-dependent signaling mechanism.Impact of elevated plasma serotonin on global gene expression of murine megakaryocytes.Actin inhibition increases megakaryocyte proplatelet formation through an apoptosis-dependent mechanism.Identifying and enriching platelet-producing human stem cell-derived megakaryocytes using factor V uptake.Role of platelets in neurodegenerative diseases: a universal pathophysiology.Ex vivo production of platelets from stem cells.Bcl-2 proteins in development, health, and disease of the hematopoietic system.Proplatelet formation in megakaryocytes is associated with endoplasmic reticulum stress.Differential regulation of the apoptotic machinery during megakaryocyte differentiation and platelet production by inhibitor of apoptosis protein Livin.Non-apoptotic functions of caspases in myeloid cell differentiation.Apoptosis is an obstacle to the differentiation of adipose-derived stromal cells into astrocytes.Normal platelet counts mask abnormal thrombopoiesis in patients with chronic myeloid leukemia.Dysregulation of the intrinsic apoptotic pathway mediates megakaryocytic hyperplasia in myeloproliferative neoplasms.Separation of in-vitro-derived megakaryocytes and platelets using spinning-membrane filtration.The Plant Hormone Abscisic Acid Is a Prosurvival Factor in Human and Murine Megakaryocytes.Inner Mitochondrial Membrane Disruption Links Apoptotic and Agonist-Initiated Phosphatidylserine Externalization in Platelets.Platelet Signaling Pathways and New Inhibitors.
P2860
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P2860
Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function.
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Caspase-9 mediates the apoptot ...... their generation and function.
@ast
Caspase-9 mediates the apoptot ...... their generation and function.
@en
type
label
Caspase-9 mediates the apoptot ...... their generation and function.
@ast
Caspase-9 mediates the apoptot ...... their generation and function.
@en
prefLabel
Caspase-9 mediates the apoptot ...... their generation and function.
@ast
Caspase-9 mediates the apoptot ...... their generation and function.
@en
P2093
P50
P1433
P1476
Caspase-9 mediates the apoptot ...... their generation and function.
@en
P2093
Chloé James
David C S Huang
Kate E Jarman
Katya J Henley
Marlyse A Debrincat
P304
P356
10.1182/BLOOD-2011-11-394858
P407
P577
2012-01-31T00:00:00Z