Identification of small-molecule inducers of pancreatic beta-cell expansion
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Emerging Role and Therapeutic Implication of Wnt Signaling Pathways in Autoimmune DiseasesProteins and small molecules for cellular regenerative medicineConcise review: in search of unlimited sources of functional human pancreatic beta cellsEpoxypukalide induces proliferation and protects against cytokine-mediated apoptosis in primary cultures of pancreatic β-cellsAdenosine kinase inhibition selectively promotes rodent and porcine islet β-cell replicationGSK3 inhibitor-BIO regulates proliferation of immortalized pancreatic mesenchymal stem cells (iPMSCs)An inverse small molecule screen to design a chemically defined medium supporting long-term growth of Drosophila cell linesAdult tissue sources for new β cells.Small-Molecule Suppressors of Cytokine-Induced beta-Cell Apoptosis.Small molecule-based disruption of the Axin/β-catenin protein complex regulates mesenchymal stem cell differentiation.A human islet cell culture system for high-throughput screening.Development of the endocrine pancreas and novel strategies for β-cell mass restoration and diabetes therapy.Identification of small molecules for human hepatocyte expansion and iPS differentiationGlucose regulates cyclin D2 expression in quiescent and replicating pancreatic β-cells through glycolysis and calcium channelsA small molecule differentiation inducer increases insulin production by pancreatic β cellsOpposing roles of voltage-gated Ca2+ channels in neuronal control of regenerative patterning.Chemical methods to induce Beta-cell proliferation.How to make beta cells?Droplet-based light-sheet fluorescence microscopy for high-throughput sample preparation, 3-D imaging and quantitative analysis on a chip.A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.An assay for small scale screening of candidate β cell proliferative factors using intact isletsHow to make a functional β-cellWS6 induces both alpha and beta cell proliferation without affecting differentiation or viability.Inhibition of DYRK1A Stimulates Human β-Cell ProliferationSynthesis at the interface of chemistry and biology.The new generation of beta-cells: replication, stem cell differentiation, and the role of small molecules.From theory to clinical practice in the use of GLP-1 receptor agonists and DPP-4 inhibitors therapy.Droplet microfluidics for high-throughput biological assays.The abluminal endothelial membrane in neurovascular remodeling in health and disease.Diabetes mellitus--advances and challenges in human β-cell proliferation.Magnetic sensing platform technologies for biomedical applications.A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform.Novel factors modulating human β-cell proliferation.Advances in β cell replacement and regeneration strategies for treating diabetesDevelopment of a reliable automated screening system to identify small molecules and biologics that promote human β-cell regenerationβ-cell preservation and regeneration for diabetes treatment: where are we now?Magnetofluidic platform for multidimensional magnetic and optical barcoding of droplets.Chemical strategies for pancreatic β cell differentiation, reprogramming, and regeneration.Inhibition of TBK1/IKKε Promotes Regeneration of Pancreatic β-cellsMelatonin attenuates detrimental effects of diabetes on the niche of mouse spermatogonial stem cells by maintaining Leydig cells
P2860
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P2860
Identification of small-molecule inducers of pancreatic beta-cell expansion
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Identification of small-molecule inducers of pancreatic beta-cell expansion
@ast
Identification of small-molecule inducers of pancreatic beta-cell expansion
@en
type
label
Identification of small-molecule inducers of pancreatic beta-cell expansion
@ast
Identification of small-molecule inducers of pancreatic beta-cell expansion
@en
prefLabel
Identification of small-molecule inducers of pancreatic beta-cell expansion
@ast
Identification of small-molecule inducers of pancreatic beta-cell expansion
@en
P2093
P2860
P356
P1476
Identification of small-molecule inducers of pancreatic beta-cell expansion
@en
P2093
Jae Wook Lee
John R Walker
Matthew S Tremblay
Peter G Schultz
P2860
P304
P356
10.1073/PNAS.0811848106
P407
P50
P577
2009-01-22T00:00:00Z