In vitro priming recapitulates in vivo HIV-1 specific T cell responses, revealing rapid loss of virus reactive CD4 T cells in acute HIV-1 infection.
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Consensus HIV-1 FSU-A integrase gene variants electroporated into mice induce polyfunctional antigen-specific CD4+ and CD8+ T cellsHIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity.Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progressionInduction of Gag-specific CD4 T cell responses during acute HIV infection is associated with improved viral control.The antiviral efficacy of HIV-specific CD8⁺ T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate.Evidence of dysregulation of dendritic cells in primary HIV infection.Complement opsonization of HIV-1 results in decreased antiviral and inflammatory responses in immature dendritic cells via CR3The immune response during acute HIV-1 infection: clues for vaccine development.Use of RT-defective HIV virions: new tool to evaluate specific response in chronic asymptomatic HIV-infected individualsExpression of a broad array of negative costimulatory molecules and Blimp-1 in T cells following priming by HIV-1 pulsed dendritic cells.Differences in HIV-specific T cell responses between HIV-exposed and -unexposed HIV-seronegative individualsAutologous aldrithiol-2-inactivated HIV-1 combined with polyinosinic-polycytidylic acid-poly-L-lysine carboxymethylcellulose as a vaccine platform for therapeutic dendritic cell immunotherapyHIV-1 impairs in vitro priming of naïve T cells and gives rise to contact-dependent suppressor T cells.Impaired NK Cell Activation and Chemotaxis toward Dendritic Cells Exposed to Complement-Opsonized HIV-1.Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells.Innate immune sensing of HIV-1 by dendritic cells.Public T cell receptors confer high-avidity CD4 responses to HIV controllersComplement opsonization of HIV-1 results in a different intracellular processing pattern and enhanced MHC class I presentation by dendritic cells.Dendritic cell dysregulation during HIV-1 infection.Dendritic cell based vaccines for HIV infection: the way ahead.Different antigen-processing activities in dendritic cells, macrophages, and monocytes lead to uneven production of HIV epitopes and affect CTL recognition.Programming T cell Killers for an HIV Cure: Teach the New Dogs New Tricks and Let the Sleeping Dogs LieAutologous and allogenic systems of HIV expansion: what is the better choice for clinical application in therapeutic vaccine?Decreased CD1a(+) , CD83(+) and factor XIIIa(+) dendritic cells in cervical lymph nodes and palatine tonsils of AIDS patients.DNA Vaccination by Electroporation Amplifies Broadly Cross-Restricted Public TCR Clonotypes Shared with HIV Controllers.Advances in dendritic cell immunotherapies for HIV-1 infection.The anti-caspase inhibitor Q-VD-OPH prevents AIDS disease progression in SIV-infected rhesus macaques.
P2860
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P2860
In vitro priming recapitulates in vivo HIV-1 specific T cell responses, revealing rapid loss of virus reactive CD4 T cells in acute HIV-1 infection.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
In vitro priming recapitulates ...... ells in acute HIV-1 infection.
@ast
In vitro priming recapitulates ...... ells in acute HIV-1 infection.
@en
type
label
In vitro priming recapitulates ...... ells in acute HIV-1 infection.
@ast
In vitro priming recapitulates ...... ells in acute HIV-1 infection.
@en
prefLabel
In vitro priming recapitulates ...... ells in acute HIV-1 infection.
@ast
In vitro priming recapitulates ...... ells in acute HIV-1 infection.
@en
P2093
P2860
P50
P1433
P1476
In vitro priming recapitulates ...... ells in acute HIV-1 infection.
@en
P2093
Daniel E Kaufmann
Daniel G Kavanagh
Ethan Babcock
Jeffrey Lifson
Karlhans Fru
Nina Bhardwaj
Rachel Lubong Sabado
P2860
P356
10.1371/JOURNAL.PONE.0004256
P407
P577
2009-01-23T00:00:00Z