about
Tetramerization of SAMHD1 is required for biological activity and inhibition of HIV infectionA Blueprint for HIV Vaccine DiscoveryEndogenous retroviruses and the development of cancerCD169-dependent cell-associated HIV-1 transmission: a driver of virus disseminationA Chimeric HIV-1 gp120 Fused with Vaccinia Virus 14K (A27) Protein as an HIV ImmunogenCD169-mediated trafficking of HIV to plasma membrane invaginations in dendritic cells attenuates efficacy of anti-gp120 broadly neutralizing antibodiesCasein kinase II controls TBK1/IRF3 activation in IFN response against viral infection.Innate Invariant NKT Cell Recognition of HIV-1-Infected Dendritic Cells Is an Early Detection Mechanism Targeted by Viral Immune Evasion.Interactions between HIV-1 and the cell-autonomous innate immune system.Small molecule inhibition of SAMHD1 dNTPase by tetramer destabilization.Mouse knockout models for HIV-1 restriction factors.Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses.A High-Throughput Enzyme-Coupled Assay for SAMHD1 dNTPase.PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1.Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile α Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors.HIV-1 vaginal transmission: cell-free or cell-associated virus?Optimization of human dendritic cell sample preparation for mass spectrometry-based proteomic studies.HIV-2 and SIVmac accessory virulence factor Vpx down-regulates SAMHD1 enzyme catalysis prior to proteasome-dependent degradationDevelopment of human dendritic cells and their role in HIV infection: antiviral immunity versus HIV transmission.SAMHD1 restricts herpes simplex virus 1 in macrophages by limiting DNA replication.Cellular and Biochemical Mechanisms of the Retroviral Restriction Factor SAMHD1.Dendritic cell-lymphocyte cross talk downregulates host restriction factor SAMHD1 and stimulates HIV-1 replication in dendritic cellsDendritic cell dysregulation during HIV-1 infection.Safeguard against DNA sensing: the role of TREX1 in HIV-1 infection and autoimmune diseases.Sindbis Virus Can Exploit a Host Antiviral Protein To Evade Immune Surveillance.The innate immune roles of host factors TRIM5α and Cyclophilin A on HIV-1 replication.Vpr Enhances Tumor Necrosis Factor Production by HIV-1-Infected T Cells.Cytosolic RNA:DNA hybrids activate the cGAS-STING axis.HIV infection: focus on the innate immune cells.Role of Innate Genes in HIV Replication.HIV Fusion in Dendritic Cells Occurs Mainly at the Surface and Is Limited by Low CD4 Levels.A molecular dynamics simulation study decodes the early stage of the disassembly process abolishing the human SAMHD1 function.HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3.HIV-1 Tat protein induces PD-L1 (B7-H1) expression on dendritic cells through tumor necrosis factor alpha- and toll-like receptor 4-mediated mechanisms.Endogenous TRIM5α Function Is Regulated by SUMOylation and Nuclear Sequestration for Efficient Innate Sensing in Dendritic Cells.SAMHD1 degradation enhances active suppression of dendritic cell maturation by HIV-1.Keeping your armour intact: how HIV-1 evades detection by the innate immune system: HIV-1 capsid controls detection of reverse transcription products by the cytosolic DNA sensor cGAS.Characterization of HIV-1 infection and innate sensing in different types of primary human monocyte-derived macrophages.Snapin promotes HIV-1 transmission from dendritic cells by dampening TLR8 signaling.Are Evolution and the Intracellular Innate Immune System Key Determinants in HIV Transmission?
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Innate immune sensing of HIV-1 by dendritic cells.
@en
type
label
Innate immune sensing of HIV-1 by dendritic cells.
@en
prefLabel
Innate immune sensing of HIV-1 by dendritic cells.
@en
P2860
P1433
P1476
Innate immune sensing of HIV-1 by dendritic cells.
@en
P2860
P304
P356
10.1016/J.CHOM.2012.10.002
P50
P577
2012-10-01T00:00:00Z