Heparanase regulates levels of syndecan-1 in the nucleus. - Wikidata - wikimedia - TriplyDB

Heparanase regulates levels of syndecan-1 in the nucleus.

Heparanase regulates levels of syndecan-1 in the nucleus.

http://www.wikidata.org/entity/Q33420350

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Proteoglycan form and function: A comprehensive nomenclature of proteoglycans Syndecan-1 in Cancer: Implications for Cell Signaling, Differentiation, and Prognostication Specific syndecan-1 domains regulate mesenchymal tumor cell adhesion, motility and migration A systems biology approach for the investigation of the heparin/heparan sulfate interactome Inhibition of PDGF-B induction and cell growth by syndecan-1 involves the ubiquitin and SUMO-1 ligase, Topors The niche factor syndecan-1 regulates the maintenance and proliferation of neural progenitor cells during mammalian cortical development Syndecan-1 and FGF-2, but not FGF receptor-1, share a common transport route and co-localize with heparanase in the nuclei of mesenchymal tumor cells.Heparanase and hepatocellular carcinoma: promoter or inhibitor?Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis.Chemical Tumor Biology of Heparan Sulfate Proteoglycans.Sulforhodamine B restaining as a whole-cell label allows visualizing one more fluorochrome and its application in assaying protein nucleocytoplasmic distribution.Heparanase enhances local and systemic osteolysis in multiple myeloma by upregulating the expression and secretion of RANKL Prognostic value of heparanase expression and cellular localization in oral cancer.Shed syndecan-1 translocates to the nucleus of cells delivering growth factors and inhibiting histone acetylation: a novel mechanism of tumor-host cross-talk.Heparanase-mediated loss of nuclear syndecan-1 enhances histone acetyltransferase (HAT) activity to promote expression of genes that drive an aggressive tumor phenotype Heparan sulfate in the nucleus and its control of cellular functions.The Profile of Heparanase Expression Distinguishes Differentiated Thyroid Carcinoma from Benign Neoplasms.Myeloma as a model for the process of metastasis: implications for therapy Significance of heparanase in cancer and inflammation.Model of fibrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cells Heparanase enhances the insulin receptor signaling pathway to activate extracellular signal-regulated kinase in multiple myeloma.An introduction to proteoglycans and their localization Immunohistochemical expression of heparanase isoforms and syndecan-1 proteins in colorectal adenomas.The endoglycosidase heparanase enters the nucleus of T lymphocytes and modulates H3 methylation at actively transcribed genes via the interplay with key chromatin modifying enzymes Heparanase: busy at the cell surface.Heparan sulfate: a ubiquitous glycosaminoglycan with multiple roles in immunity Heparanase and autoimmune diabetes.Serglycin proteoglycan is required for multiple myeloma cell adhesion, in vivo growth, and vascularization.Glycosaminoglycans: key players in cancer cell biology and treatment.The heparanase/syndecan-1 axis in cancer: mechanisms and therapies.The role of syndecan-1 in cellular signaling and its effects on heparan sulfate biosynthesis in mesenchymal tumors Heparanase: a rainbow pharmacological target associated to multiple pathologies including rare diseases.Insights into the molecular roles of heparan sulfate proteoglycans (HSPGs-syndecans) in autocrine and paracrine growth factor signaling in the pathogenesis of Hodgkin's lymphoma.Sulfation patterns determine cellular internalization of heparin-like polysaccharides.A comparative study of syndecan-1 expression in different odontogenic tumors.High glucose facilitated endothelial heparanase transfer to the cardiomyocyte modifies its cell death signature.Two promoters with distinct activities in different tissues drive the expression of heparanase in Xenopus.Hepatoprotective and anti-tumor effects of targeting MMP-9 in hepatocellular carcinoma and its relation to vascular invasion markers.Dually modified transmembrane proteoglycans in development and disease.Molecular targets and signaling pathways regulated by nuclear translocation of syndecan-1.

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P2860

Heparanase regulates levels of syndecan-1 in the nucleus.

http://www.wikidata.org/entity/Q33420350

description

2009 nî lūn-bûn

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2009 թուականի Մարտին հրատարակուած գիտական յօդուած

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2009 թվականի մարտին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Heparanase regulates levels of syndecan-1 in the nucleus.

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Heparanase regulates levels of syndecan-1 in the nucleus.

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Heparanase regulates levels of syndecan-1 in the nucleus.

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Heparanase regulates levels of syndecan-1 in the nucleus.

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Heparanase regulates levels of syndecan-1 in the nucleus.

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Heparanase regulates levels of syndecan-1 in the nucleus.

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Heparanase regulates levels of syndecan-1 in the nucleus.

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Ligong Chen

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Ralph D Sanderson

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P2860

Sequence of human syndecan indicates a novel gene family of integral membrane proteoglycans

Processing and activation of latent heparanase occurs in lysosomes

Identification of active-site residues of the pro-metastatic endoglycosidase heparanase

Soluble syndecan-1 promotes growth of myeloma tumors in vivo

Histone acetyltransferases

Regulation of heparan sulfate proteoglycan nuclear localization by fibronectin.

Immunoreactivity to cell surface syndecans in cytoplasm and nucleus: tubulin-dependent rearrangements.

Molecular polymorphism of a cell surface proteoglycan: distinct structures on simple and stratified epithelia

The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy.

Glypican and biglycan in the nuclei of neurons and glioma cells: presence of functional nuclear localization signals and dynamic changes in glypican during the cell cycle

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