Genetic variance in the adiponutrin gene family and childhood obesity.
about
Genetic & epigenetic approach to human obesityLoss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesityThe PNPLA3 rs738409 G-allele associates with reduced fasting serum triglyceride and serum cholesterol in Danes with impaired glucose regulationIn vitro gene regulatory networks predict in vivo function of liverThe association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver diseasePatatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease.Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome.PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease.Mammalian triacylglycerol metabolism: synthesis, lipolysis, and signalingLarge common deletions associate with mortality at old age.Homocysteine suppresses lipolysis in adipocytes by activating the AMPK pathway.Inhibition of ERK1/2 pathway suppresses adiponectin secretion via accelerating protein degradation by Ubiquitin-proteasome system: relevance to obesity-related adiponectin decline.Interactions of allelic variance of PNPLA3 with nongenetic factors in predicting nonalcoholic steatohepatitis and nonhepatic complications of severe obesity.Non-alcoholic fatty liver disease and metabolic syndrome in adolescents: pathogenetic role of genetic background and intrauterine environment.Genetic variants in candidate genes influencing NAFLD progression.Identification of human patatin-like phospholipase domain-containing protein 1 and a mutant in human cervical cancer HeLa cells.Molecular dynamics simulation of PNPLA3 I148M polymorphism reveals reduced substrate access to the catalytic cavity.Genetic variants in COL13A1, ADIPOQ and SAMM50, in addition to the PNPLA3 gene, confer susceptibility to elevated transaminase levels in an admixed Mexican population.
P2860
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P2860
Genetic variance in the adiponutrin gene family and childhood obesity.
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Genetic variance in the adiponutrin gene family and childhood obesity.
@ast
Genetic variance in the adiponutrin gene family and childhood obesity.
@en
type
label
Genetic variance in the adiponutrin gene family and childhood obesity.
@ast
Genetic variance in the adiponutrin gene family and childhood obesity.
@en
prefLabel
Genetic variance in the adiponutrin gene family and childhood obesity.
@ast
Genetic variance in the adiponutrin gene family and childhood obesity.
@en
P2093
P2860
P1433
P1476
Genetic variance in the adiponutrin gene family and childhood obesity
@en
P2093
Claude Marcus
Lina M Johansson
Lovisa E Johansson
Martin Ridderstråle
Stina Johansson
Svante Norgren
P2860
P356
10.1371/JOURNAL.PONE.0005327
P407
P577
2009-04-24T00:00:00Z