In vivo antitumor effect of a novel inhibitor of protein geranylgeranyltransferase-I
about
Cancer of the Pancreas: Molecular Pathways and Current Advancement in TreatmentApproaches of targeting Rho GTPases in cancer drug discoveryDeleted in liver cancer-1 (DLC1): an emerging metastasis suppressor geneIdentification and characterization of mechanism of action of P61-E7, a novel phosphine catalysis-based inhibitor of geranylgeranyltransferase-IMelanoma cells treated with GGTI and IFN-gamma allow murine vaccination and enhance cytotoxic response against human melanoma cells.Targeting protein prenylation for cancer therapyA novel approach to tag and identify geranylgeranylated proteins.Diversity through phosphine catalysis identifies octahydro-1,6-naphthyridin-4-ones as activators of endothelium-driven immunity.Geranylgeranyltransferase I is essential for dendritic development of cerebellar Purkinje cells.Phosphine-catalyzed [4+2] annulations of 2-alkylallenoates and olefins: synthesis of multisubstituted cyclohexenesDiversity-oriented synthesis based on the DPPP-catalyzed mixed double-Michael reactions of electron-deficient acetylenes and β-amino alcohols.Hydroxyproline-derived pseudoenantiomeric [2.2.1] bicyclic phosphines: asymmetric synthesis of (+)- and (-)-pyrrolines.PHOSPHINE-CATALYZED [3 + 2] ANNULATION: SYNTHESIS OF ETHYL 5-(tert-BUTYL)-2-PHENYL-1-TOSYL-3-PYRROLINE-3-CARBOXYLATEIn vitro and in vivo effects of geranylgeranyltransferase I inhibitor P61A6 on non-small cell lung cancer cellsThe RalGEF-Ral Effector Signaling Network: The Road Less Traveled for Anti-Ras Drug Discovery.Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesisSevere hepatocellular disease in mice lacking one or both CaaX prenyltransferases.Nanoformulation of Geranylgeranyltransferase-I Inhibitors for Cancer Therapy: Liposomal Encapsulation and pH-Dependent Delivery to Cancer Cells.Advances in nucleophilic phosphine catalysis of alkenes, allenes, alkynes, and MBHADs.Nucleophilic Chiral Phosphines: Powerful and Versatile Catalysts for Asymmetric AnnulationsA mouse model of luciferase-transfected stromal cells of giant cell tumor of bone.Rac1 in human diseases: The therapeutic potential of targeting Rac1 signaling regulatory mechanisms.Involvement of RalB in the effect of geranylgeranyltransferase I on glioma cell migration and invasion.Regulatory properties of statins and rho gtpases prenylation inhibitiors to stimulate melanoma immunogenicity and promote anti-melanoma immune response.Molecular pathways driving disease-specific alterations of intestinal epithelial cells.Geranylgeranyltransferase I regulates HIF-1α promoting glioblastoma cell migration and invasion.Geranylgeranyltransferase I promotes human glioma cell growth through Rac1 membrane association and activation.Rho GTPases as therapeutic targets in cancer (Review).Phosphine-catalyzed intramolecular γ-umpolung addition of α-aminoalkylallenic esters: facile synthesis of 3-carbethoxy-2-alkyl-3-pyrrolines.Preclinical investigation of a potent geranylgeranyl diphosphate synthase inhibitor.PPh3-catalyzed ring-expansion reactions of sulfamate-derived cyclic imines with acetylenedicarboxylates.
P2860
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P2860
In vivo antitumor effect of a novel inhibitor of protein geranylgeranyltransferase-I
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
In vivo antitumor effect of a novel inhibitor of protein geranylgeranyltransferase-I
@ast
In vivo antitumor effect of a novel inhibitor of protein geranylgeranyltransferase-I
@en
type
label
In vivo antitumor effect of a novel inhibitor of protein geranylgeranyltransferase-I
@ast
In vivo antitumor effect of a novel inhibitor of protein geranylgeranyltransferase-I
@en
prefLabel
In vivo antitumor effect of a novel inhibitor of protein geranylgeranyltransferase-I
@ast
In vivo antitumor effect of a novel inhibitor of protein geranylgeranyltransferase-I
@en
P2093
P2860
P1476
In vivo antitumor effect of a novel inhibitor of protein geranylgeranyltransferase-I
@en
P2093
Fuyuhiko Tamanoi
Hannah D G Fiji
Ohyun Kwon
Russell Dahl
P2860
P304
P356
10.1158/1535-7163.MCT-08-1122
P577
2009-05-05T00:00:00Z