Inhibition of dynamin mediated endocytosis by the dynoles--synthesis and functional activity of a family of indoles.
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Pitstop 2 is a potent inhibitor of clathrin-independent endocytosisPharmacological inhibition of dynamin II reduces constitutive protein secretion from primary human macrophagesMultiplex assay for live-cell monitoring of cellular fates of amyloid-β precursor protein (APP)Synaptotagmin-11 inhibits clathrin-mediated and bulk endocytosisMolecular mechanism and physiological functions of clathrin-mediated endocytosisPhenothiazine-derived antipsychotic drugs inhibit dynamin and clathrin-mediated endocytosis.Regulation of dynamin oligomerization in cells: the role of dynamin-actin interactions and its GTPase activity.Building a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosis.Investigating signaling consequences of GPCR trafficking in the endocytic pathway.The Rhodadyns, a New Class of Small Molecule Inhibitors of Dynamin GTPase Activity.At the crossroads of chemistry and cell biology: inhibiting membrane traffic by small molecules.The intracellular trafficking pathway of transferrin.Analysis of synaptic vesicle endocytosis in synaptosomes by high-content screening.Molecular mechanism of constitutive endocytosis of Acid-sensing ion channel 1a and its protective function in acidosis-induced neuronal death.Dopamine transporter endocytic trafficking in striatal dopaminergic neurons: differential dependence on dynamin and the actin cytoskeleton.Combining valosin-containing protein (VCP) inhibition and suberanilohydroxamic acid (SAHA) treatment additively enhances the folding, trafficking, and function of epilepsy-associated γ-aminobutyric acid, type A (GABAA) receptorsSorting nexin 9 recruits clathrin heavy chain to the mitotic spindle for chromosome alignment and segregation.Dynamin inhibitors induce caspase-mediated apoptosis following cytokinesis failure in human cancer cells and this is blocked by Bcl-2 overexpression.Dynamin inhibition blocks botulinum neurotoxin type A endocytosis in neurons and delays botulismIntracellular curvature-generating proteins in cell-to-cell fusion.1,8-Naphthalimide derivatives: new leads against dynamin I GTPase activity.Phosphatidylserine dynamics in cellular membranes.Deficiency in the Lipid Exporter ABCA1 Impairs Retrograde Sterol Movement and Disrupts Sterol Sensing at the Endoplasmic ReticulumDynamin2 controls Rap1 activation and integrin clustering in human T lymphocyte adhesionSynthesis of 2-arylindole derivatives and evaluation as nitric oxide synthase and NFκB inhibitors.Inhibition of clathrin by pitstop 2 activates the spindle assembly checkpoint and induces cell death in dividing HeLa cancer cells.Search for inhibitors of endocytosis: Intended specificity and unintended consequences.Integrin endosomal signalling suppresses anoikis.Actin bundling by dynamin 2 and cortactin is implicated in cell migration by stabilizing filopodia in human non-small cell lung carcinoma cells.Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitorsFluorescent aminoglycosides reveal intracellular trafficking routes in mechanosensory hair cells.Cellular uptake and intracellular trafficking of oligonucleotidesDynasore - not just a dynamin inhibitor.Cellular mechanism of fibril formation from serum amyloid A1 protein.Distinct functions of dynamin isoforms in tumorigenesis and their potential as therapeutic targets in cancer.Endophilin marks and controls a clathrin-independent endocytic pathway.Validation of an algorithm to quantify changes in actin cytoskeletal organization.Dynamin inhibitors impair endocytosis and mitogenic signaling of PDGF.Clathrin-independent trafficking of AMPA receptors.A Cholesterol-Dependent Endocytic Mechanism Generates Midbody Tubules During Cytokinesis.
P2860
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P2860
Inhibition of dynamin mediated endocytosis by the dynoles--synthesis and functional activity of a family of indoles.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
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2009年の論文
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2009年学术文章
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2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
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2009年學術文章
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name
Inhibition of dynamin mediated ...... tivity of a family of indoles.
@ast
Inhibition of dynamin mediated ...... tivity of a family of indoles.
@en
type
label
Inhibition of dynamin mediated ...... tivity of a family of indoles.
@ast
Inhibition of dynamin mediated ...... tivity of a family of indoles.
@en
prefLabel
Inhibition of dynamin mediated ...... tivity of a family of indoles.
@ast
Inhibition of dynamin mediated ...... tivity of a family of indoles.
@en
P2093
P50
P356
P1476
Inhibition of dynamin mediated ...... tivity of a family of indoles.
@en
P2093
Andrew B McGeachie
Anna Mariana
Annie Quan
Barbara Venn-Brown
Luke R Odell
Megan Chircop
P304
P356
10.1021/JM900036M
P407
P577
2009-06-01T00:00:00Z