Diverse effects of individual mismatch repair components on transcription-induced CAG repeat instability in human cells.
about
New insights into repeat instability: role of RNA•DNA hybridsDNA mismatch repair system: repercussions in cellular homeostasis and relationship with agingImpact of DNA mismatch repair system alterations on human fertility and related treatmentsDNA MMR systems, microsatellite instability and antioxidant activity variations in two species of wild bats: Myotis velifer and Desmodus rotundus, as possible factors associated with longevityProcessing of double-R-loops in (CAG)·(CTG) and C9orf72 (GGGGCC)·(GGCCCC) repeats causes instability.Convergent transcription through a long CAG tract destabilizes repeats and induces apoptosisR loops stimulate genetic instability of CTG.CAG repeats.Topoisomerase 1 and single-strand break repair modulate transcription-induced CAG repeat contraction in human cells.Xpa deficiency reduces CAG trinucleotide repeat instability in neuronal tissues in a mouse model of SCA1.X inactivation plays a major role in the gender bias in somatic expansion in a mouse model of the fragile X-related disorders: implications for the mechanism of repeat expansion.DNA methyltransferases, DNA damage repair, and cancerNucleotide excision repair, mismatch repair, and R-loops modulate convergent transcription-induced cell death and repeat instabilityDefining genetic factors that modulate intergenerational CAG repeat instability in Drosophila melanogasterProteomic-coupled-network analysis of T877A-androgen receptor interactomes can predict clinical prostate cancer outcomes between White (non-Hispanic) and African-American groupsMismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approachesLarge expansion of CTG•CAG repeats is exacerbated by MutSβ in human cells.Instability of (CTG)n•(CAG)n trinucleotide repeats and DNA synthesisA DNA repair pathway-focused score for prediction of outcomes in ovarian cancer treated with platinum-based chemotherapyMutsβ generates both expansions and contractions in a mouse model of the Fragile X-associated disordersHuman mismatch repair protein hMutLα is required to repair short slipped-DNAs of trinucleotide repeats.The dual nature of mismatch repair as antimutator and mutator: for better or for worse.Transcription-induced DNA toxicity at trinucleotide repeats: double bubble is trouble.Mismatch repair enhances convergent transcription-induced cell death at trinucleotide repeats by activating ATR.Convergent transcription through microsatellite repeat tracts induces cell death.Fanconi anemia pathway regulates convergent transcription-induced cell death at trinucleotide repeats in human cells.Characterization of Camptothecin-induced Genomic Changes in the Camptothecin-resistant T-ALL-derived Cell Line CPT-K5.Genetic instability associated with loop or stem-loop structures within transcription units can be independent of nucleotide excision repair.
P2860
Q24621985-6BFB295D-8F71-410B-9E1D-55F9AD03519BQ26995348-68F43E60-0E25-48D7-907D-2AEAF707D50CQ28074585-7312B44D-A551-4259-AFD4-8B2E5B85E371Q28710242-22FA5DD6-0D9A-444F-8A30-63F102357793Q30409374-4B978B66-D4B9-4C6E-BB37-5A2AA40342E5Q33637169-6600B287-6308-4497-8DDB-951102B705ADQ33639972-EE39FD75-3006-464F-A7AD-3FE97A6BFD58Q33917909-F7980AEA-80A9-4830-B6E4-585B505EE447Q34021533-6EBB3C35-C3C6-48CA-B0DF-BFA2605A875AQ34074533-29F7F289-7ADE-4CC5-BE18-6B310DE3B7A7Q34298096-43B509F2-74CE-46F0-9135-8F671140E7CAQ34442152-5CEFBC46-D481-444B-9C2C-79B4A104B5ECQ34477635-EC930AB6-6950-4349-9780-990AB900E177Q34542337-9FE3BCA6-30E5-4FFA-8884-19C20A7DF7E8Q35034398-86CB7E24-0285-4EF4-989E-3B01554CD482Q35687467-F2E6BBED-A589-45C1-A16F-C0A6C903EB83Q35847997-5906BE54-BA43-4CE8-B182-F2C1005EAAA8Q35925499-5ED44FFB-AD58-4CBA-92CC-3AC103684A9BQ36302118-96A70D3C-6312-4FE1-A7CC-3DA96B408F03Q36451916-B0E01DA1-3E4A-4707-B3A8-DEF04575AF9BQ38246275-C2D74A7F-807D-4451-9BAA-E9534954C014Q38448720-266DA0D7-8DD2-44D1-B40A-DD586A1D0864Q38774203-0B6431BC-202A-4701-BC4A-85D251DB0CCDQ38976458-9731E42C-E963-4BDA-83CC-96C0D7475A3FQ40985893-5B0CFD1D-8460-4F70-AFF5-A9512825D71DQ52678451-26FF8F37-AB02-45A5-B4F2-1D0989493BE9Q52688242-442B12CA-5F81-4500-A718-0F5B60BC60D2
P2860
Diverse effects of individual mismatch repair components on transcription-induced CAG repeat instability in human cells.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Diverse effects of individual ...... at instability in human cells.
@ast
Diverse effects of individual ...... at instability in human cells.
@en
type
label
Diverse effects of individual ...... at instability in human cells.
@ast
Diverse effects of individual ...... at instability in human cells.
@en
prefLabel
Diverse effects of individual ...... at instability in human cells.
@ast
Diverse effects of individual ...... at instability in human cells.
@en
P2860
P1433
P1476
Diverse effects of individual ...... at instability in human cells.
@en
P2093
John H Wilson
P2860
P304
P356
10.1016/J.DNAREP.2009.04.024
P577
2009-06-03T00:00:00Z