Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver. - Wikidata - wikimedia - TriplyDB

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver.

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver.

http://www.wikidata.org/entity/Q33480591

about

OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies Tramadol Extended-Release for the Management of Pain due to Osteoarthritis Role of the plasma membrane transporter of organic cations OCT1 and its genetic variants in modern liver pharmacology Role of solute carriers in response to anticancer drugs AMPK activation through mitochondrial regulation results in increased substrate oxidation and improved metabolic parameters in models of diabetes Hepatocyte nuclear factor 1 regulates the expression of the organic cation transporter 1 via binding to an evolutionary conserved region in intron 1 of the OCT1 gene DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma Metformin as a new anti-cancer drug in adrenocortical carcinoma Proton pump inhibitors inhibit metformin uptake by organic cation transporters (OCTs)The Role of Metformin Response in Lipid Metabolism in Patients with Recent-Onset Type 2 Diabetes: HbA1c Level as a Criterion for Designating Patients as Responders or Nonresponders to Metformin Polymorphic variation in TPMT is the principal determinant of TPMT phenotype: A meta-analysis of three genome-wide association studies.Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A).Pharmacogenomics of Drug Response in Type 2 Diabetes: Toward the Definition of Tailored Therapies?Genetically polymorphic OCT1: another piece in the puzzle of the variable pharmacokinetics and pharmacodynamics of the opioidergic drug tramadol.Common drugs inhibit human organic cation transporter 1 (OCT1)-mediated neurotransmitter uptake.The role of genetic factors and kidney and liver function in glycemic control in type 2 diabetes patients on long-term metformin and sulphonylurea cotreatment.Lobe-specific heterogeneity in asymmetric dimethylarginine and matrix metalloproteinase levels in a rat model of obstructive cholestasis Bile formation and secretion.Genetic polymorphisms and haplotypes of the organic cation transporter 1 gene (SLC22A1) in the Xhosa population of South Africa Biliary excretion of imatinib and its active metabolite CGP74588 during severe hepatic dysfunction.OCT1 genetic variants influence the pharmacokinetics of morphine in children.An update on the pharmacogenomics of metformin: progress, problems and potential.Mechanisms of drug-induced liver injury: from bedside to bench.Taste of a pill: organic cation transporter-3 (OCT3) mediates metformin accumulation and secretion in salivary glands.Role of organic cation transporter 3 (SLC22A3) and its missense variants in the pharmacologic action of metformin Verapamil decreases the glucose-lowering effect of metformin in healthy volunteers Organic cation transporter variation and response to smoking cessation therapies Intake of St John's wort improves the glucose tolerance in healthy subjects who ingest metformin compared with metformin alone.Nucleoside transporter proteins as biomarkers of drug responsiveness and drug targets.Metformin as an energy restriction mimetic agent for breast cancer prevention A solute carrier family 22 member 3 variant rs3088442 G→A associated with coronary heart disease inhibits lipopolysaccharide-induced inflammatory response.Paraoxonase (PON1 and PON3) Polymorphisms: Impact on Liver Expression and Atorvastatin-Lactone Hydrolysis Pathway-Targeted Pharmacogenomics of CYP1A2 in Human Liver.Effect of culture time on the basal expression levels of drug transporters in sandwich-cultured primary rat hepatocytes Hepatic expression of detoxification enzymes is decreased in human obstructive cholestasis due to gallstone biliary obstruction Drug Transporters and Na+/H+ Exchange Regulatory Factor PSD-95/Drosophila Discs Large/ZO-1 Proteins Global genetic analyses reveal strong inter-ethnic variability in the loss of activity of the organic cation transporter OCT1.Genetic and epigenetic regulation of the organic cation transporter 3, SLC22A3.Genetic variants of OCT1 influence glycemic response to metformin in Han Chinese patients with type-2 diabetes mellitus in Shanghai.Phylogenetic, syntenic, and tissue expression analysis of slc22 genes in zebrafish (Danio rerio).

P2860

Q27001267-75266EE3-824B-46D3-AFA3-8DD8E2D16730 Q27015822-5CB57E4E-7EEF-4AB3-B4C2-B32E6B8BDFCE Q27026858-70A47A79-4922-4E14-9629-2EA8B759561D Q27027625-076DFC68-7E48-47FC-BC48-FCEAF686CF18 Q27300811-B0BE5227-95FD-4E89-8AA2-FB97BE0BAB32 Q28296115-B4C45AF5-B46F-4F62-91AD-1B77E80BAE5E Q28383720-F89A5761-C1B7-4CCC-9149-9E7A0FFDD8F7 Q28468634-9375EBEE-D0C1-4C46-8E5A-B8378D1B5E9D Q28479037-385FBCF4-C09A-48E8-992A-74351A83B64D Q28550746-29B2F7C7-E9E8-4B9E-AC1F-87BDFF857FB5 Q30244222-AFFA20A2-D969-4A13-90D8-606877FE8936 Q30353578-1D8AA586-BF85-4C0F-8BB5-0746997BD087 Q30388214-A74766A9-8837-4DCC-99C7-F56FE062D849 Q33351201-BB1AFAC0-38BE-4A52-8CE4-4435B56C1802 Q33584577-C781733E-5EF9-4B6D-9D70-AA52526DDD63 Q33804241-60BB1B1A-FC2B-4F2B-A5AD-CFC82A0B66B4 Q33821707-B4B259E8-59DB-43DF-85D8-B903450D4A8E Q33881922-22D83EB6-CC4D-4973-A97A-D0B09550755E Q33890370-AD50B513-850D-4CEC-B4C8-B38311EEE86E Q33908105-A6972BB0-8F94-41AF-806C-47819BEB37C4 Q33977906-0915CB38-DA8F-4B7E-BBD1-915905910F36 Q34003050-562CE321-9044-418C-B05B-18D68929B11E Q34169362-EE12646C-9EC4-4FE6-853B-6895CEC456B7 Q34245062-02A3F04E-79AB-4E47-BBCC-B6A4288D0989 Q34292557-237BF23D-41E9-4F3E-A649-D9D4209AF779 Q34635590-AC384C32-7977-436C-AFBF-EA4200346005 Q34974830-6127F50F-C34C-435A-88F5-F88EF0CE4BDD Q35023736-4DD2E3D3-32BE-4003-8B9E-AE5081351C3E Q35066350-4B831E70-5847-4ADF-A298-E6F1811AB03D Q35125473-5856DB4B-5228-4243-8747-91CEEDDA79AC Q35126576-6D038088-267F-4D9D-8B78-13E9D2D9786B Q35138221-7D42BCA3-AC75-429E-9F2E-E6E0D084D53B Q35210306-2594B194-BCAA-46F0-BAFE-93DBEB8B42DB Q35579531-1B4CDF64-A420-4365-A082-262E07F6115B Q35583781-491145E2-1080-4B39-9FC9-641E79049898 Q35795744-EE3D6E2A-0F44-4043-B758-881BC5A71636 Q35831346-01DE4580-6D8F-468B-8381-123DA2EF05E3 Q36095058-6B9D436A-487F-48A6-8E1D-AFB248738E63 Q36095402-1DF32DC0-F5A9-4352-B01E-461CC7829125 Q36103220-C2235A4B-2857-4277-9B14-96996678CC59

P2860

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver.

http://www.wikidata.org/entity/Q33480591

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Expression of organic cation t ...... nd cholestasis in human liver.

@ast

Expression of organic cation t ...... nd cholestasis in human liver.

@en

type

label

Expression of organic cation t ...... nd cholestasis in human liver.

@ast

Expression of organic cation t ...... nd cholestasis in human liver.

@en

prefLabel

Expression of organic cation t ...... nd cholestasis in human liver.

@ast

Expression of organic cation t ...... nd cholestasis in human liver.

@en

P1433

Q33480591-199A1738-AB93-482D-897D-9C48D3BB07C2

P1476

Q33480591-AE57F0C7-2CEF-4D22-AC61-0BB45FD85C8F

P2093

Q33480591-09DB4479-2D42-430B-82C2-3685E25824BE

Q33480591-10D34AC4-107E-46E1-8675-583644DAFDDF

Q33480591-50D57583-468A-4E05-B8FB-854CC5268B6B

Q33480591-75DDCE68-FEC1-4B6B-AFCB-33E89EAEEFE2

Q33480591-B7297F0A-529C-4DCC-AE3A-076D1CB1FB8C

Q33480591-EBDD5346-0238-42BA-BF2B-1FA2E89492F5

Q33480591-FC18E943-8964-4C32-B52B-18161B74DDB7

P2860

Q33480591-0207D195-E716-4534-87D6-3511E209CD2E

Q33480591-089898EC-6149-42EC-81BF-44A6508BAC66

Q33480591-0FE2413E-BD6E-4085-A6F3-AAB00295D525

Q33480591-15EF8A7F-1FCB-4A68-8E5C-98CA9A471597

Q33480591-21137EDA-782C-4AD6-8A02-AB6B01DDB8FF

Q33480591-253C3FD7-BC5C-4AD7-ACD8-08702DCEBF3D

Q33480591-27D6DCFD-292D-472D-AFAD-B8E65289D96A

Q33480591-29A3F403-86CC-49E0-803F-9BCF5A70B485

Q33480591-2B7F79AF-5829-4247-B042-560E56FE4C62

Q33480591-2BA52D38-AC88-4B49-8F62-812E8B1E1787

P304

Q33480591-07AEB83E-8B31-4547-93B1-BDB9153DC246

P31

Q33480591-9F5FA722-5FBB-44DF-832E-57DE7BFFFB42

P356

Q33480591-0690AFD9-D72F-464B-8A5A-B74EC6907169

P407

Q33480591-D7ABED2B-075A-4CDD-8594-8C94BB8DFEA2

P433

Q33480591-68E9F2BB-BFBA-4B6E-87FA-A8D90F2D2023

P478

Q33480591-2B833267-1C58-445D-91DC-8C6A9D50F5B7

P50

Q33480591-1CAD7FAA-B347-4813-978F-B2D04E0451E4

Q33480591-B8F1F9B0-15C5-4C3B-BA9F-0D0386B5FDA9

Q33480591-EB9EBE85-D210-4D10-9BA8-4D65CA902F0A

P577

Q33480591-DDBF777E-E17F-491C-BE5F-83C8006E5224

P698

Q33480591-77BE128C-5261-4E0A-A37F-B183109750E5

P356

P1433

P1476

Expression of organic cation t ...... nd cholestasis in human liver.

@en

P2093

Dietrich Keppler

http://www.w3.org/2001/XMLSchema#string

Hermann Koepsell

http://www.w3.org/2001/XMLSchema#string

Kathrin Klein

http://www.w3.org/2001/XMLSchema#string

Matthias Schwab

http://www.w3.org/2001/XMLSchema#string

Oliver Burk

http://www.w3.org/2001/XMLSchema#string

Reinhold Kerb

http://www.w3.org/2001/XMLSchema#string

Stefan Winter

http://www.w3.org/2001/XMLSchema#string

P2860

Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27

Cloning and characterization of two human polyspecific organic cation transporters

A note on exact tests of Hardy-Weinberg equilibrium

Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1

A New Statistical Method for Haplotype Reconstruction from Population Data

The International HapMap Project

Haploview: analysis and visualization of LD and haplotype maps

Transport of lamivudine [(-)-beta-L-2',3'-dideoxy-3'-thiacytidine] and high-affinity interaction of nucleoside reverse transcriptase inhibitors with human organic cation transporters 1, 2, and 3

The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteinsIntroduction

cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 predominantly expressed in the human kidney

P304

1227-1240

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/HEP.23103

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

50

http://www.w3.org/2001/XMLSchema#string

P50

Elke Schaeffeler

Ulrich M. Zanger

P577

2009-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

19591196

http://www.w3.org/2001/XMLSchema#string