Platelet membrane defects in Glanzmann's thrombasthenia. Evidence for decreased amounts of two major glycoproteins
about
Direct demonstration of involvement of protein kinase Calpha in the Ca2+-induced platelet aggregationTargeting leukocyte integrins in human diseasesThe origins of the molecular era of adhesion research.Localization of human platelet autoantigens to the cysteine-rich region of glycoprotein IIIa.The GPIIb/IIIa (integrin alphaIIbbeta3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend.Thrombocytopenia in the intensive care unit.Platelet 12-LOX is essential for FcγRIIa-mediated platelet activation.αIIbβ3 variants defined by next-generation sequencing: predicting variants likely to cause Glanzmann thrombasthenia.Thrombocytopenia--radial aplasia (TAR) syndrome with associated immune thrombocytopenia.Deletion of the platelet-specific alloantigen PlA1 from platelets in Glanzmann's thrombastheniaExposure of platelet fibrinogen receptors by ADP and epinephrine.Monocytes and platelets share the glycoproteins IIb and IIIa that are absent from both cells in Glanzmann's thrombasthenia type I.Platelet membrane glycoprotein IIIa contains target antigens that bind anti-platelet antibodies in immune thrombocytopenias.Molecular cloning of the alpha subunit of human and guinea pig leukocyte adhesion glycoprotein Mo1: chromosomal localization and homology to the alpha subunits of integrinsPhysical linkage of the genes for platelet membrane glycoproteins IIb and IIIa.Platelets have more than one binding site for von Willebrand factor.Glanzmann thrombasthenia resulting from a single amino acid substitution between the second and third calcium-binding domains of GPIIb. Role of the GPIIb amino terminus in integrin subunit associationA new variant of Glanzmann's thrombasthenia (Strasbourg I). Platelets with functionally defective glycoprotein IIb-IIIa complexes and a glycoprotein IIIa 214Arg----214Trp mutation.Imaging thrombus with radiolabelled monoclonal antibody to platelets.Exposure of fibrinogen receptors in human platelets by surface proteolysis with elastase.A monoclonal antibody to human platelet glycoprotein IIIa detects a related protein in cultured human endothelial cells.Linkage of a membrane skeleton to integral membrane glycoproteins in human platelets. Identification of one of the glycoproteins as glycoprotein IbA variant of Glanzmann's thrombasthenia with abnormal glycoprotein IIb-IIIa complexes in the platelet membrane.Integrin targeted therapeutics.Continuing education course #2: current understanding of hemostasis.Reduced surface expression and binding of fibronectin by thrombin-stimulated thrombasthenic platelets.Effects of monoclonal antibodies against the platelet glycoprotein IIb/IIIa complex on thrombosis and hemostasis in the baboon.Biogenesis of the platelet receptor for fibrinogen: evidence for separate precursors for glycoproteins IIb and IIIa.Identification of membrane proteins mediating the interaction of human platelets.Concanavalin A induces interactions between surface glycoproteins and the platelet cytoskeleton.Ultrastructure of clots during isometric contraction.Actin filament content and organization in unstimulated plateletsRedistribution of the fibrinogen receptor of human platelets after surface activation.Isolation of a subpopulation of glycoprotein IIb-III from platelet membranes that is bound to membrane actin.A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activationGlycoprotein Ic-IIa functions as an activation-independent fibronectin receptor on human platelets.Glanzmann thrombasthenia: deficient binding of von Willebrand factor to thrombin-stimulated platelets.Human megakaryocytes. II. Expression of platelet proteins in early marrow megakaryocytesInheritance of the human platelet alloantigen, PlA1, in type I Glanzmann's thrombastheniaIntegrin αIIbβ3: from discovery to efficacious therapeutic target
P2860
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P2860
Platelet membrane defects in Glanzmann's thrombasthenia. Evidence for decreased amounts of two major glycoproteins
description
1977 nî lūn-bûn
@nan
1977 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1977 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1977年の論文
@ja
1977年論文
@yue
1977年論文
@zh-hant
1977年論文
@zh-hk
1977年論文
@zh-mo
1977年論文
@zh-tw
1977年论文
@wuu
name
Platelet membrane defects in G ...... nts of two major glycoproteins
@ast
Platelet membrane defects in G ...... nts of two major glycoproteins
@en
type
label
Platelet membrane defects in G ...... nts of two major glycoproteins
@ast
Platelet membrane defects in G ...... nts of two major glycoproteins
@en
prefLabel
Platelet membrane defects in G ...... nts of two major glycoproteins
@ast
Platelet membrane defects in G ...... nts of two major glycoproteins
@en
P2860
P356
P1476
Platelet membrane defects in G ...... nts of two major glycoproteins
@en
P2093
P2860
P304
P356
10.1172/JCI108805
P407
P577
1977-09-01T00:00:00Z