Novel Bcl-2 homology-3 domain-like sequences identified from screening randomized peptide libraries for inhibitors of the pro-survival Bcl-2 proteins.

Novel Bcl-2 homology-3 domain-like sequences identified from screening randomized peptide libraries for inhibitors of the pro-survival Bcl-2 proteins.

Item
http://www.wikidata.org/entity/Q33502518
Mutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosisDeterminants of BH3 Binding Specificity for Mcl-1 versus Bcl-xLDiscovery and molecular characterization of a Bcl-2-regulated cell death pathway in schistosomesStructure-Guided Rational Design of α/β-Peptide Foldamers with High Affinity for BCL-2 Family Prosurvival ProteinsIntrinsically disordered proteins in bcl-2 regulated apoptosis.Identification of a novel Mcl-1 protein binding motifProtein binding specificity versus promiscuity.Locating Herpesvirus Bcl-2 Homologs in the Specificity Landscape of Anti-Apoptotic Bcl-2 Proteins.Bcl-2, Bcl-x(L), and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cellsEvolution of Bcl-2 homology motifs: homology versus homoplasy.Predictive Bcl-2 family binding models rooted in experiment or structure.Drugs targeting Bcl-2 family members as an emerging strategy in cancer.Design of novel BH3 mimetics for the treatment of chronic lymphocytic leukemia.BH3-triggered structural reorganization drives the activation of proapoptotic BAX.In silico and in vitro elucidation of BH3 binding specificity toward Bcl-2Designed BH3 peptides with high affinity and specificity for targeting Mcl-1 in cells.Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells.
P2860

Novel Bcl-2 homology-3 domain-like sequences identified from screening randomized peptide libraries for inhibitors of the pro-survival Bcl-2 proteins.

Item
http://www.wikidata.org/entity/Q33502518
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Novel Bcl-2 homology-3 domain- ...... e pro-survival Bcl-2 proteins.
@ast
Novel Bcl-2 homology-3 domain- ...... e pro-survival Bcl-2 proteins.
@en
type
label
Novel Bcl-2 homology-3 domain- ...... e pro-survival Bcl-2 proteins.
@ast
Novel Bcl-2 homology-3 domain- ...... e pro-survival Bcl-2 proteins.
@en
prefLabel
Novel Bcl-2 homology-3 domain- ...... e pro-survival Bcl-2 proteins.
@ast
Novel Bcl-2 homology-3 domain- ...... e pro-survival Bcl-2 proteins.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Novel Bcl-2 homology-3 domain- ...... he pro-survival Bcl-2 proteins
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932