The plasminogen activation system enhances brain and heart invasion in murine relapsing fever borreliosis.
about
Borrelia recurrentis employs a novel multifunctional surface protein with anti-complement, anti-opsonic and invasive potential to escape innate immunityBorrelia burgdorferi, host-derived proteases, and the blood-brain barrierThe urokinase receptor (uPAR) facilitates clearance of Borrelia burgdorferiEvidence that two ATP-dependent (Lon) proteases in Borrelia burgdorferi serve different functionsStructural conservation of neurotropism-associated VspA within the variable Borrelia Vsp-OspC lipoprotein family.A disconnect between the neurospirochetoses in humans and rodent models of disease.Platelet activation by a relapsing fever spirochaete results in enhanced bacterium-platelet interaction via integrin alphaIIbbeta3 activation.Genetic control of the innate immune response to Borrelia hermsii influences the course of relapsing fever in inbred strains of mice.Concomitant infection decreases the malaria burden but escalates relapsing fever borreliosisInfection-stimulated fibrin deposition controls hemorrhage and limits hepatic bacterial growth during listeriosisPhylogenetic analysis of a virulent Borrelia species isolated from patients with relapsing fever.Borrelia spirochetes upregulate release and activation of matrix metalloproteinase gelatinase B (MMP-9) and collagenase 1 (MMP-1) in human cellsIsogenic serotypes of Borrelia turicatae show different localization in the brain and skin of mice.Cardiac apoptosis in severe relapsing fever borreliosis.Toll-like receptor 2 deficiency results in impaired antibody responses and septic shock during Borrelia hermsii infection.Group B Streptococcus hijacks the host plasminogen system to promote brain endothelial cell invasionEnolase: a key player in the metabolism and a probable virulence factor of trypanosomatid parasites-perspectives for its use as a therapeutic target.The plasminogen activator/plasmin system is essential for development of the joint inflammatory phase of collagen type II-induced arthritisInteraction of a neurotropic strain of Borrelia turicatae with the cerebral microcirculation system.Dual role of MyD88 in rapid clearance of relapsing fever Borrelia sppCharacteristics of Borrelia hermsii infection in human hematopoietic stem cell-engrafted mice mirror those of human relapsing fever.The enolase of Borrelia burgdorferi is a plasminogen receptor released in outer membrane vesicles.OspC is potent plasminogen receptor on surface of Borrelia burgdorferi.The versatile roles of antibodies in Borrelia infections.Bacterial plasminogen receptors utilize host plasminogen system for effective invasion and dissemination.The HtrA protease of Borrelia burgdorferi degrades outer membrane protein BmpD and chemotaxis phosphatase CheX.Understanding tropism and immunopathological mechanisms of relapsing fever spirochaetes.Efficient B cell responses to Borrelia hermsii infection depend on BAFF and BAFFR but not TACI.Interaction of spirochetes with the host fibrinolytic system and potential roles in pathogenesis.Bacterial pathogens activate plasminogen to breach tissue barriers and escape from innate immunity.Delayed invasion of the kidney and brain by Borrelia crocidurae in plasminogen-deficient miceMolecular characterization of the interaction of Borrelia parkeri and Borrelia turicatae with human complement regulators.Roles for phagocytic cells and complement in controlling relapsing fever infection.Testicular damage by microcirculatory disruption and colonization of an immune-privileged site during Borrelia crocidurae infectionVariable small protein (Vsp)-dependent and Vsp-independent pathways for glycosaminoglycan recognition by relapsing fever spirochaetes.Blood-brain barrier invasion by Cryptococcus neoformans is enhanced by functional interactions with plasmin.The Complement Binding and Inhibitory Protein CbiA of Borrelia miyamotoi Degrades Extracellular Matrix Components by Interacting with Plasmin(ogen).Relapsing Fevers: Neglected Tick-Borne Diseases.Microbiological features distinguishing Lyme disease and relapsing fever spirochetes
P2860
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P2860
The plasminogen activation system enhances brain and heart invasion in murine relapsing fever borreliosis.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
The plasminogen activation sys ...... e relapsing fever borreliosis.
@ast
The plasminogen activation sys ...... e relapsing fever borreliosis.
@en
type
label
The plasminogen activation sys ...... e relapsing fever borreliosis.
@ast
The plasminogen activation sys ...... e relapsing fever borreliosis.
@en
prefLabel
The plasminogen activation sys ...... e relapsing fever borreliosis.
@ast
The plasminogen activation sys ...... e relapsing fever borreliosis.
@en
P2093
P2860
P356
P1476
The plasminogen activation sys ...... e relapsing fever borreliosis.
@en
P2093
P2860
P356
10.1172/JCI5171
P407
P577
1999-01-01T00:00:00Z