Tn-seq: high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms
about
Control of virulence by small RNAs in Streptococcus pneumoniaeHigh-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolismGenome-scale engineering for systems and synthetic biologyThe interplay between intestinal bacteria and host metabolism in health and disease: lessons from Drosophila melanogasterHuman microbiomes and their roles in dysbiosis, common diseases, and novel therapeutic approachesWhole-genome sequencing targets drug-resistant bacterial infectionsBiofilms and Inflammation in Chronic WoundsRecent advances in pneumococcal peptidoglycan biosynthesis suggest new vaccine and antimicrobial targetsARTIST: high-resolution genome-wide assessment of fitness using transposon-insertion sequencingInterplay of the serine/threonine-kinase StkP and the paralogs DivIVA and GpsB in pneumococcal cell elongation and divisionComprehensive assignment of roles for Salmonella typhimurium genes in intestinal colonization of food-producing animalsLong-term single cell analysis of S. pombe on a microfluidic microchemostat arrayData-driven integration of genome-scale regulatory and metabolic network modelsGenome-wide analyses of small non-coding RNAs in streptococciGlobal assessment of genomic regions required for growth in Mycobacterium tuberculosisRequirements for Pseudomonas aeruginosa acute burn and chronic surgical wound infectionA genetic strategy for probing the functional diversity of magnetosome formationStrain Dependent Genetic Networks for Antibiotic-Sensitivity in a Bacterial Pathogen with a Large Pan-GenomeToward a Predictive Understanding of Earth's Microbiomes to Address 21st Century ChallengesThe functional basis of adaptive evolution in chemostatsDEG 10, an update of the database of essential genes that includes both protein-coding genes and noncoding genomic elementsIntegration profiling of gene function with dense maps of transposon integrationBiological and Chemical Adaptation to Endogenous Hydrogen Peroxide Production in Streptococcus pneumoniae D39Analysis of the Caenorhabditis elegans innate immune response to Coxiella burnetiiPIMMS (Pragmatic Insertional Mutation Mapping System) Laboratory Methodology a Readily Accessible Tool for Identification of Essential Genes in StreptococcusRetrospective application of transposon-directed insertion site sequencing to a library of signature-tagged mini-Tn5Km2 mutants of Escherichia coli O157:H7 screened in cattle.Identifying microbial fitness determinants by insertion sequencing using genome-wide transposon mutant librariesESSENTIALS: software for rapid analysis of high throughput transposon insertion sequencing data.Requirement of essential Pbp2x and GpsB for septal ring closure in Streptococcus pneumoniae D39.Essential genome of Pseudomonas aeruginosa in cystic fibrosis sputum.High-resolution definition of the Vibrio cholerae essential gene set with hidden Markov model-based analyses of transposon-insertion sequencing dataA Hidden Markov Model for identifying essential and growth-defect regions in bacterial genomes from transposon insertion sequencing data.qDNAmod: a statistical model-based tool to reveal intercellular heterogeneity of DNA modification from SMRT sequencing data.Evidence-based annotation of gene function in Shewanella oneidensis MR-1 using genome-wide fitness profiling across 121 conditions.A comparison of dense transposon insertion libraries in the Salmonella serovars Typhi and Typhimurium.Combining Shigella Tn-seq data with gold-standard E. coli gene deletion data suggests rare transitions between essential and non-essential gene functionality.Combining quantitative genetic footprinting and trait enrichment analysis to identify fitness determinants of a bacterial pathogenImplementation and Data Analysis of Tn-seq, Whole-Genome Resequencing, and Single-Molecule Real-Time Sequencing for Bacterial Genetics.The highly conserved bacterial RNase YbeY is essential in Vibrio cholerae, playing a critical role in virulence, stress regulation, and RNA processingIntegration of 'omics' data: does it lead to new insights into host-microbe interactions?
P2860
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P2860
Tn-seq: high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Tn-seq: high-throughput parall ...... tion studies in microorganisms
@ast
Tn-seq: high-throughput parall ...... tion studies in microorganisms
@en
type
label
Tn-seq: high-throughput parall ...... tion studies in microorganisms
@ast
Tn-seq: high-throughput parall ...... tion studies in microorganisms
@en
prefLabel
Tn-seq: high-throughput parall ...... tion studies in microorganisms
@ast
Tn-seq: high-throughput parall ...... tion studies in microorganisms
@en
P2860
P356
P1433
P1476
Tn-seq: high-throughput parall ...... tion studies in microorganisms
@en
P2093
Andrew Camilli
Kip L Bodi
P2860
P2888
P304
P356
10.1038/NMETH.1377
P577
2009-09-20T00:00:00Z
P5875
P6179
1008876804