about
Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin ZProtein-Directed Dynamic Combinatorial Chemistry: A Guide to Protein Ligand and Inhibitor DiscoveryFluorescence anisotropy (polarization): from drug screening to precision medicine.Targeting UDP-galactopyranose mutases from eukaryotic human pathogensLessons from the past and charting the future of marine natural products drug discovery and chemical biologyDirect assembling methodologies for high-throughput bioscreeningDevelopment and validation of an automated high-throughput system for zebrafish in vivo screeningsContribution of high-content imaging technologies to the development of anti-infective drugsPubChem as a public resource for drug discoveryMapping drug physico-chemical features to pathway activity reveals molecular networks linked to toxicity outcomeSystematic exploitation of multiple receptor conformations for virtual ligand screeningFormalization, annotation and analysis of diverse drug and probe screening assay datasets using the BioAssay Ontology (BAO)An ultra high-throughput, whole-animal screen for small molecule modulators of a specific genetic pathway in Caenorhabditis elegansA versatile, bar-coded nuclear marker/reporter for live cell fluorescent and multiplexed high content imagingKnowledge-based fragment binding predictionRise of the micromachines: microfluidics and the future of cytometryPlate-based diversity subset screening generation 2: an improved paradigm for high-throughput screening of large compound filesImproving drug discovery with high-content phenotypic screens by systematic selection of reporter cell linesRepositioning of the anthelmintic drug mebendazole for the treatment for colon cancerChallenges in secondary analysis of high throughput screening dataIntelligence and Creativity in Problem Solving: The Importance of Test Features in Cognition ResearchQuantification of frequent-hitter behavior based on historical high-throughput screening data.Screening_mgmt: a Python module for managing screening data.Data-driven approaches used for compound library design, hit triage and bioactivity modeling in high-throughput screening.Aging biology and novel targets for drug discovery.Bis-aryloxadiazoles as effective activators of the aryl hydrocarbon receptor.BioAssay ontology annotations facilitate cross-analysis of diverse high-throughput screening data sets.Mining the ChEMBL database: an efficient chemoinformatics workflow for assembling an ion channel-focused screening library20 years of DNA-encoded chemical libraries.High-resolution dose-response screening using droplet-based microfluidics.Gaining confidence in high-throughput screening.From laptop to benchtop to bedside: structure-based drug design on protein targets.Discovery of small-molecule interleukin-2 inhibitors from a DNA-encoded chemical library.Analyzing fission yeast multidrug resistance mechanisms to develop a genetically tractable model system for chemical biology.The multicellular tumor spheroid model for high-throughput cancer drug discovery.Concise review: a high-content screening approach to stem cell research and drug discovery.Mining collections of compounds with Screening Assistant 2Phenylalanine hydroxylase misfolding and pharmacological chaperones.Target identification and mechanism of action in chemical biology and drug discovery.Plate-based diversity subset screening: an efficient paradigm for high throughput screening of a large screening file.
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
name
Novel trends in high-throughput screening.
@ast
Novel trends in high-throughput screening.
@en
type
label
Novel trends in high-throughput screening.
@ast
Novel trends in high-throughput screening.
@en
prefLabel
Novel trends in high-throughput screening.
@ast
Novel trends in high-throughput screening.
@en
P1476
Novel trends in high-throughput screening.
@en
P2093
Dejan Bojanic
Lorenz M Mayr
P304
P356
10.1016/J.COPH.2009.08.004
P577
2009-09-21T00:00:00Z