Functional, non-clonal IgMa-restricted B cell receptor interactions with the HIV-1 envelope gp41 membrane proximal external region.

Functional, non-clonal IgMa-restricted B cell receptor interactions with the HIV-1 envelope gp41 membrane proximal external region.

Item
http://www.wikidata.org/entity/Q33508799
Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus MacaquesIsolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sorting.A versatile vector for the production of pseudotyped viruses expressing gp120 antigens from different clades of primary HIV-1 isolates.9G4+ antibodies isolated from HIV-infected patients neutralize HIV-1 and have distinct autoreactivity profiles.Role of immune mechanisms in induction of HIV-1 broadly neutralizing antibodies.Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls.Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutatedClonal analysis of human anti-V3 monoclonal antibodies selected by a V3 tetramerCommon tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineagesModulation of nonneutralizing HIV-1 gp41 responses by an MHC-restricted TH epitope overlapping those of membrane proximal external region broadly neutralizing antibodies.Enhanced antibody responses to an HIV-1 membrane-proximal external region antigen in mice reconstituted with cultured lymphocytes.Immunologic characteristics of HIV-infected individuals who make broadly neutralizing antibodies.Immune perturbations in HIV-1-infected individuals who make broadly neutralizing antibodies.Efficient role of IgH 3' regulatory region deficient B-cells in the development of oil granulomas.Induction of HIV-1 broad neutralizing antibodies in 2F5 knock-in mice: selection against membrane proximal external region-associated autoreactivity limits T-dependent responses.
P2860

Functional, non-clonal IgMa-restricted B cell receptor interactions with the HIV-1 envelope gp41 membrane proximal external region.

Item
http://www.wikidata.org/entity/Q33508799
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Functional, non-clonal IgMa-re ...... rane proximal external region.
@ast
Functional, non-clonal IgMa-re ...... rane proximal external region.
@en
type
label
Functional, non-clonal IgMa-re ...... rane proximal external region.
@ast
Functional, non-clonal IgMa-re ...... rane proximal external region.
@en
prefLabel
Functional, non-clonal IgMa-re ...... rane proximal external region.
@ast
Functional, non-clonal IgMa-re ...... rane proximal external region.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Functional, non-clonal IgMa-re ...... rane proximal external region.
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0007215
P407
P433
P478
P50
P577
P5875
P698
P932