Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls. - Wikidata - wikimedia - TriplyDB

Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls.

Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls.

http://www.wikidata.org/entity/Q35336374

about

HIV-Host Interactions: Implications for Vaccine Design Resolve, revise, and relax: the 3 Rs of B cell repertoire adjustment HIV-1 neutralizing antibodies: understanding nature's pathways HIV-1 antibodies from infection and vaccination: insights for guiding vaccine design Progress in HIV-1 vaccine development.A Little Help From the Follicles: Understanding the Germinal Center Response to Human Immunodeficiency Virus 1 Infection and Prophylactic Vaccines.Humanized Immunoglobulin Mice: Models for HIV Vaccine Testing and Studying the Broadly Neutralizing Antibody Problem.Generation of Long-Lived Bone Marrow Plasma Cells Secreting Antibodies Specific for the HIV-1 gp41 Membrane-Proximal External Region in the Absence of Polyreactivity.Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity.Autoreactivity in HIV-1 broadly neutralizing antibodies: implications for their function and induction by vaccination.B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies Liver immunology.Polyreactivity and autoreactivity among HIV-1 antibodies.HIV-1 envelope gp41 broadly neutralizing antibodies: hurdles for vaccine development.A systematic review of syphilis serological treatment outcomes in HIV-infected and HIV-uninfected persons: rethinking the significance of serological non-responsiveness and the serofast state after therapy.BLyS-mediated modulation of naive B cell subsets impacts HIV Env-induced antibody responses.Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.HIV-1 gp140 epitope recognition is influenced by immunoglobulin DH gene segment sequence.Anti-HIV B Cell lines as candidate vaccine biosensors.Lessons learned from HIV-1 vaccine trials: new priorities and directions Development of prophylactic vaccines against HIV-1.Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10 Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10 Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages Functional Versatility of AGY Serine Codons in Immunoglobulin Variable Region Genes.Progress toward active or passive HIV-1 vaccination.Modulation of nonneutralizing HIV-1 gp41 responses by an MHC-restricted TH epitope overlapping those of membrane proximal external region broadly neutralizing antibodies.BCR and Endosomal TLR Signals Synergize to Increase AID Expression and Establish Central B Cell Tolerance.An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.HIV Diagnosis and Treatment through Advanced Technologies.Enhanced antibody responses to an HIV-1 membrane-proximal external region antigen in mice reconstituted with cultured lymphocytes.Polyreactive antibodies in adaptive immune responses to viruses.Role of human immunodeficiency virus type 1 envelope structure in the induction of broadly neutralizing antibodies.Immune System Regulation in the Induction of Broadly Neutralizing HIV-1 Antibodies.Breaching peripheral tolerance promotes the production of HIV-1-neutralizing antibodies.Human Ig knockin mice to study the development and regulation of HIV-1 broadly neutralizing antibodies.Antibody-virus co-evolution in HIV infection: paths for HIV vaccine development.Immunologic characteristics of HIV-infected individuals who make broadly neutralizing antibodies.Host controls of HIV broadly neutralizing antibody development.

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Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls.

http://www.wikidata.org/entity/Q35336374

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Rescue of HIV-1 broad neutrali ...... s multiple tolerance controls.

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Rescue of HIV-1 broad neutrali ...... s multiple tolerance controls.

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Rescue of HIV-1 broad neutrali ...... s multiple tolerance controls.

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Rescue of HIV-1 broad neutrali ...... s multiple tolerance controls.

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Rescue of HIV-1 broad neutrali ...... s multiple tolerance controls.

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JIMMUNOL.1101633

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Journal of Immunology

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Rescue of HIV-1 broad neutrali ...... s multiple tolerance controls.

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Hilary Bouton-Verville

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Jennifer Hutchinson

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Jinsong Zhang

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Kwan-Ki Hwang

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Laurent Verkoczy

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Marilyn Diaz

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S Munir Alam

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T Matt Holl

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Yao Chen

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Ying-Bin Ouyang

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P2860

Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1

A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies

Antibody neutralization and escape by HIV-1

Rapid evolution of the neutralizing antibody response to HIV type 1 infection

HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

Functional, non-clonal IgMa-restricted B cell receptor interactions with the HIV-1 envelope gp41 membrane proximal external region.

Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance

Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sorting.

Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope.

The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes.

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2011-09-09T00:00:00Z

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