HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells
about
Structure-function relationships of ErbB RTKs in the plasma membrane of living cellsOrchestration of ErbB3 signaling through heterointeractions and homointeractions.Model-based analysis of HER activation in cells co-expressing EGFR, HER2 and HER3Cyclooxygenase-2 is a novel transcriptional target of the nuclear EGFR-STAT3 and EGFRvIII-STAT3 signaling axesProtein secretion in human mammary epithelial cells following HER1 receptor activation: influence of HER2 and HER3 expression.Evolution of breast cancer therapeutics: Breast tumour kinase's role in breast cancer and hope for breast tumour kinase targeted therapyEssential role of the cancer stem/progenitor cell marker nucleostemin for indole-3-carbinol anti-proliferative responsiveness in human breast cancer cells.Profiling epidermal growth factor receptor and heregulin receptor 3 heteromerization using receptor tyrosine kinase heteromer investigation technology.HER-3 peptide vaccines/mimics: Combined therapy with IGF-1R, HER-2, and HER-1 peptides induces synergistic antitumor effects against breast and pancreatic cancer cellsHeregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines.Integrated analysis reveals that STAT3 is central to the crosstalk between HER/ErbB receptor signaling pathways in human mammary epithelial cells.Spatial aspects in biological system simulationsIntegrated experimental and model-based analysis reveals the spatial aspects of EGFR activation dynamics.ADAM10-mediated release of heregulin confers resistance to trastuzumab by activating HER3.An anti-HER2 antibody conjugated with monomethyl auristatin E is highly effective in HER2-positive human gastric cancer.HER2-HER3 dimer quantification by FLIM-FRET predicts breast cancer metastatic relapse independently of HER2 IHC status.erbB3 is an active tyrosine kinase capable of homo- and heterointeractions.Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance.EGFR signaling pathways are wired differently in normal 184A1L5 human mammary epithelial and MDA-MB-231 breast cancer cells.Systems analysis of drug-induced receptor tyrosine kinase reprogramming following targeted mono- and combination anti-cancer therapy.Multiplexed Exchange-PAINT imaging reveals ligand-dependent EGFR and Met interactions in the plasma membrane.Cell type influences the molecular mechanisms involved in hormonal regulation of ERG K+ channels.Amplified Ras-MAPK signal states correlate with accelerated EGFR internalization, cytostasis and delayed HER2 tumor onset in Fer-deficient model systems.
P2860
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P2860
HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells
@ast
HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells
@en
HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells.
@nl
type
label
HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells
@ast
HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells
@en
HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells.
@nl
prefLabel
HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells
@ast
HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells
@en
HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells.
@nl
P2093
P2860
P356
P1433
P1476
HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells
@en
P2093
Haluk Resat
Harish Shankaran
Lee Opresko
William B Chrisler
P2860
P2888
P356
10.1186/1471-2121-10-78
P50
P577
2009-10-31T00:00:00Z
P5875
P6179
1034440769