An anticoagulant RNA aptamer that inhibits proteinase-cofactor interactions within prothrombinase
about
Selection of an aptamer antidote to the anticoagulant drug bivalirudinModulation of the Coagulation Cascade Using AptamersSelection and characterization of a DNA aptamer inhibiting coagulation factor XIa.Probing the coagulation pathway with aptamers identifies combinations that synergistically inhibit blood clot formation.Targeting tumor cell invasion and dissemination in vivo by an aptamer that inhibits urokinase-type plasminogen activator through a novel multifunctional mechanism.Evaluation of antithrombotic activity of thrombin DNA aptamers by a murine thrombosis model.Notecarin D binds human factor V and factor Va with high affinity in the absence of membranes.A bipartite autoinhibitory region within the B-domain suppresses function in factor VTargeting Two Coagulation Cascade Proteases with a Bivalent Aptamer Yields a Potent and Antidote-Controllable Anticoagulant.Restoring the procofactor state of factor Va-like variants by complementation with B-domain peptidesA high affinity, antidote-controllable prothrombin and thrombin-binding RNA aptamer inhibits thrombin generation and thrombin activity.Trends in the Design and Development of Specific Aptamers Against Peptides and Proteins.Inhibiting the intrinsic pathway of coagulation with a factor XII-targeting RNA aptamer.The influence of hindered transport on the development of platelet thrombi under flow.Discovery methods of coagulation-inhibiting drugs.A kallikrein-targeting RNA aptamer inhibits the intrinsic pathway of coagulation and reduces bradykinin release.
P2860
Q28487700-D37A241E-14EB-4496-8027-295E72D1D995Q28816936-28171147-BA40-43A4-AE6D-4668320AB3D8Q33704680-8E69B81C-39EF-427C-96B7-DF5DDB3BF2D6Q34052471-E3817B7A-4369-4AE5-A4F9-132B45CB2E14Q34434875-1FBB9932-B055-43E7-9CCA-7546CC11E62AQ35239708-7E703452-D02C-48BC-B2C8-CF5EBA661BB4Q35516000-59A3D392-DB64-45CA-BBA3-0DD2AB41D015Q36122255-1408B824-FB55-478F-8849-65E1076248B1Q36580126-01226482-38AC-47AE-9A94-6E6A827CF5B8Q37233988-85BD467A-B65B-4BDC-B4CC-0DD259309FE5Q38327215-964A1275-748A-421C-9E12-12E0E01A1A61Q38777639-C24810D6-B316-46FA-BA00-D356350BBCC1Q42922540-B32D1F99-954D-4794-8E2B-9C754885C4C4Q46207575-239B0471-76BE-4E0F-9E1F-100CBFCFA699Q47737710-E2A24F7F-C1BE-4CF7-B473-D06575FABFD8Q50575704-775DE438-164E-418C-8FA7-FF9952CD6E67
P2860
An anticoagulant RNA aptamer that inhibits proteinase-cofactor interactions within prothrombinase
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
An anticoagulant RNA aptamer t ...... ractions within prothrombinase
@ast
An anticoagulant RNA aptamer t ...... ractions within prothrombinase
@en
An anticoagulant RNA aptamer t ...... actions within prothrombinase.
@nl
type
label
An anticoagulant RNA aptamer t ...... ractions within prothrombinase
@ast
An anticoagulant RNA aptamer t ...... ractions within prothrombinase
@en
An anticoagulant RNA aptamer t ...... actions within prothrombinase.
@nl
prefLabel
An anticoagulant RNA aptamer t ...... ractions within prothrombinase
@ast
An anticoagulant RNA aptamer t ...... ractions within prothrombinase
@en
An anticoagulant RNA aptamer t ...... actions within prothrombinase.
@nl
P2093
P2860
P356
P1476
An anticoagulant RNA aptamer t ...... ractions within prothrombinase
@en
P2093
Bruce A Sullenger
Christopher P Rusconi
Juliana M Layzer
Sai K Buddai
Sriram Krishnaswamy
P2860
P304
P356
10.1074/JBC.M109.049833
P407
P577
2009-12-18T00:00:00Z