Identification and pharmacological properties of E339-3D6, the first nonpeptidic apelin receptor agonist.
about
Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular systemFluorescent approaches for understanding interactions of ligands with G protein coupled receptorsThe APJ receptor: a new therapeutic approach in diabetic treatmentRegulation of the Apelinergic System and Its Potential in Cardiovascular Disease: Peptides and Small Molecules as Tools for Discovery.Oxidative stress and metabolic pathologies: from an adipocentric point of view.Biased signaling favoring gi over β-arrestin promoted by an apelin fragment lacking the C-terminal phenylalanineApelin receptor (APJ) expression during cardiopulmonary bypass in children undergoing surgical repair.The complex regulation of tanshinone IIA in rats with hypertension-induced left ventricular hypertrophyLoss of Apelin exacerbates myocardial infarction adverse remodeling and ischemia-reperfusion injury: therapeutic potential of synthetic Apelin analogues.Apelin, diabetes, and obesity.Update on apelin peptides as putative targets for cardiovascular drug discovery.Therapeutic implications of peptide interactions with G-protein-coupled receptors in diabetic vasculopathy.Apelin/APJ system: a promising therapy target for hypertension.NMDA receptor modulation by the neuropeptide apelin: implications for excitotoxic injuryDiscovery of a novel small molecule agonist scaffold for the APJ receptor.Directed Molecular Evolution of an Engineered Gammaretroviral Envelope Protein with Dual Receptor Use Shows Stable Maintenance of Both Receptor Specificities.Cardiac action of the first G protein biased small molecule apelin agonist.Effect of apelin on the cardiac hemodynamics in hypertensive rats with heart failure.By interacting with the C-terminal Phe of apelin, Phe255 and Trp259 in helix VI of the apelin receptor are critical for internalization.A Time-Resolved FRET Cell-Based Binding Assay for the Apelin Receptor.Pyrene-Apelin Conjugation Modulates Fluorophore- and Peptide-Micelle Interactions.Development of Potent and Metabolically Stable APJ Ligands with High Therapeutic Potential.Convenient Access to Fluorescent Probes by Chemoselective Acylation of Hydrazinopeptides: Application to the Synthesis of the First Far-Red Ligand for Apelin Receptor Imaging.A Non-imaging High Throughput Approach to Chemical Library Screening at the Unmodified Adenosine-A3 Receptor in Living Cells.Apelin receptor signaling: a novel mechanism of endothelial cell polarization.Discovery of a competitive apelin receptor (APJ) antagonist.Apelinergic System Structure and Function.Patent highlights: December 2015-January 2016.
P2860
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P2860
Identification and pharmacological properties of E339-3D6, the first nonpeptidic apelin receptor agonist.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Identification and pharmacolog ...... tidic apelin receptor agonist.
@ast
Identification and pharmacolog ...... tidic apelin receptor agonist.
@en
Identification and pharmacolog ...... tidic apelin receptor agonist.
@nl
type
label
Identification and pharmacolog ...... tidic apelin receptor agonist.
@ast
Identification and pharmacolog ...... tidic apelin receptor agonist.
@en
Identification and pharmacolog ...... tidic apelin receptor agonist.
@nl
prefLabel
Identification and pharmacolog ...... tidic apelin receptor agonist.
@ast
Identification and pharmacolog ...... tidic apelin receptor agonist.
@en
Identification and pharmacolog ...... tidic apelin receptor agonist.
@nl
P2093
P50
P356
P1433
P1476
Identification and pharmacolog ...... tidic apelin receptor agonist.
@en
P2093
Alain Berdeaux
Bernard Maigret
Catherine Llorens-Cortes
Christel Franchet
Fabrice Guillier
Hadjila Chabane
Jean-Luc Galzi
Marcel Hibert
Melissande Le Jouan
Nadia De Mota
P304
P356
10.1096/FJ.09-140715
P407
P577
2009-12-29T00:00:00Z