Anti-dsDNA antibodies promote initiation, and acquired loss of renal Dnase1 promotes progression of lupus nephritis in autoimmune (NZBxNZW)F1 mice.
about
Disturbances of apoptotic cell clearance in systemic lupus erythematosusImpairment of neutrophil extracellular trap degradation is associated with lupus nephritisMechanisms of Kidney Injury in Lupus Nephritis - the Role of Anti-dsDNA AntibodiesLinking susceptibility genes and pathogenesis mechanisms using mouse models of systemic lupus erythematosusMesangial cell-specific antibodies are central to the pathogenesis of lupus nephritisThe Role of Anti-DNA Antibodies in the Development of Lupus Nephritis: A Complementary, or Alternative, Viewpoint?Mechanisms of tissue injury in lupus nephritisAmelioration of lupus nephritis by serum amyloid P component gene therapy with distinct mechanisms varied from different stage of the disease.Pathways leading to an immunological disease: systemic lupus erythematosus.Renal Dnase1 enzyme activity and protein expression is selectively shut down in murine and human membranoproliferative lupus nephritisSilencing of renal DNaseI in murine lupus nephritis imposes exposure of large chromatin fragments and activation of Toll like receptors and the Clec4e.Lessons from an anti-DNA autoantibody.Acquired loss of renal nuclease activity is restricted to DNaseI and is an organ-selective feature in murine lupus nephritis.TNFα Amplifies DNaseI Expression in Renal Tubular Cells while IL-1β Promotes Nuclear DNaseI Translocation in an Endonuclease-Inactive FormAnti-DNA autoantibodies initiate experimental lupus nephritis by binding directly to the glomerular basement membrane in mice.A subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources.Role of hsp90 in systemic lupus erythematosus and its clinical relevanceLMW heparin prevents increased kidney expression of proinflammatory mediators in (NZBxNZW)F1 miceNuclease deficiencies promote end-stage lupus nephritis but not nephritogenic autoimmunity in (NZB × NZW) F1 mice.Regulatory and pathogenetic mechanisms of autoantibodies in SLE.Chromatin as a target antigen in human and murine lupus nephritisStructural modification of DNA--a therapeutic option in SLE?Autoantibodies and resident renal cells in the pathogenesis of lupus nephritis: getting to know the unknown.Neutrophil extracellular traps in sterile inflammation: the story after dying?Immunity and autoimmunity to dsDNA and chromatin--the role of immunogenic DNA-binding proteins and nuclease deficiencies.Lupus nephritis: enigmas, conflicting models and an emerging concept.The pathogenesis and diagnosis of systemic lupus erythematosus: still not resolved.The effect of cell death in the initiation of lupus nephritis.The anti-DNA antibody: origin and impact, dogmas and controversies.Expanding the B Cell-Centric View of Systemic Lupus Erythematosus.Clinical phenotype associations with various types of anti-dsDNA antibodies in patients with recent onset of rheumatic symptoms. Results from a multicentre observational studyEvaluation of anti-nuclear antibodies and kidney pathology in Lewis rats following exposure to Libby amphibole asbestos.Alterations in Wnt pathway activity in mouse serum and kidneys during lupus development.Lupus nephritis progression in FcγRIIB-/-yaa mice is associated with early development of glomerular electron dense deposits and loss of renal DNase I in severe disease.Circulating cell-free DNA concentration and DNase I activity of peripheral blood plasma change in case of pregnancy with intrauterine growth restriction compared to normal pregnancy.Plasma Cell Depletion Attenuates Hypertension in an Experimental Model of Autoimmune Disease.Antroquinonol differentially modulates T cell activity and reduces interleukin-18 production, but enhances Nrf2 activation, in murine accelerated severe lupus nephritis.Transcriptomic profiling in human mesangial cells using patient-derived lupus autoantibodies identified miR-10a as a potential regulator of IL8.IL-1β Promotes a New Function of DNase I as a Transcription Factor for the Fas Receptor Gene.Kinetics of circulating cell-free DNA for biomedical applications: critical appraisal of the literature.
P2860
Q21195358-4AFF4CFD-D9A3-417B-8B0D-6C84143F8EC7Q24606320-7459381B-B7DC-4756-867F-46A940AACE01Q26781272-C4756D69-44C2-41FC-A510-2EEFD0E586ECQ26822662-6044D6E9-E249-48ED-9F70-0079784F2609Q26991887-D90BF96C-15AB-4603-9A9C-FF0B2D68CBE8Q28085243-57A0AE3F-8EA4-45C9-A3CE-FA2D8CFFB369Q28383739-DACC306F-7AA8-4ACC-BA65-27E4868A1AC0Q31028838-14AE07BD-284C-4D9E-9A85-BA4E89FAAA5BQ33620555-66F54311-E857-4DF2-B7AF-B5C0FC7CC64CQ33697979-54FB5940-E6EC-4DD2-A552-224065CC7708Q34222085-DB209F20-7335-41AC-9A33-9ACB3C254216Q35013745-BC0A101F-90D5-4779-AF1E-68A3D393A725Q35167886-2A62CE41-EA15-4B5F-8450-0406794656C1Q35660895-E53B195E-CF73-4718-B7E0-E2FCBF1A73ADQ35931319-38CE165F-BD33-418E-BE8B-DEB2360900C7Q35951268-1A66DF9E-3E2C-4488-B79B-E88DA3DC333BQ36317684-FA9A70EE-1990-4035-9493-B324D1200C88Q37212277-35E8C5CC-2175-4736-A577-8441FD08BFFFQ37765141-58DBB108-10D7-41BB-9416-B4A0D1C4580DQ37828164-F3BFC0C4-D6F9-40B6-B88B-0441E7335270Q37872038-E5CE9491-A264-446F-B0AC-42EE60797C23Q37947116-858A0D69-1CE0-46B1-B1F9-FC0F0966FFE0Q38023852-6490473B-15B7-43B4-A507-4E8B46D89417Q38038666-55A17ECD-1E83-43F9-89BF-089392A2BD3AQ38046639-C26F7C7E-3862-4B93-BD93-6CE1D507DAC5Q38113421-6CEE89A0-9B87-46AC-9ED9-7BC7CC92B9EBQ38206945-98DACD2B-4B3E-4544-96A8-A9AF5C7BBF8DQ38231647-F30EE44C-DC8F-4A6F-8A62-0C8019BA28BAQ38512653-0CC62C4B-4FC8-4CC2-940C-EC9C6804A3A8Q39169139-B920B2C9-85DC-4328-A8F6-9AC1A645B90AQ42553554-6D82E4E3-9E4A-4C8B-874E-248BB8C8B874Q44269649-3EDB9E7D-BFF9-4051-88E8-209801BA1AD7Q44596887-65DC0905-BE21-41EA-9E41-C0809A89E95AQ47111503-1B89B012-8E38-479D-9818-2DEA5C17E370Q47163092-37F609D3-5CA5-4731-A2BD-C0D6F3C0B1A4Q47548339-0547CD79-F1F6-4BD1-A28F-F5D18D1C65BCQ50036922-4B1208B6-A765-419D-98B2-7C641B20EF60Q50131911-EC22D843-ECDC-4B87-BC3C-5B0F09CEC8EBQ50240436-7562F1ED-46FF-4AC6-9D99-4BA2FC568EDDQ52571170-60BFE7D8-9118-4AC6-8955-73C0DBD5FC2B
P2860
Anti-dsDNA antibodies promote initiation, and acquired loss of renal Dnase1 promotes progression of lupus nephritis in autoimmune (NZBxNZW)F1 mice.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Anti-dsDNA antibodies promote ...... n autoimmune (NZBxNZW)F1 mice.
@ast
Anti-dsDNA antibodies promote ...... n autoimmune (NZBxNZW)F1 mice.
@en
Anti-dsDNA antibodies promote ...... n autoimmune (NZBxNZW)F1 mice.
@nl
type
label
Anti-dsDNA antibodies promote ...... n autoimmune (NZBxNZW)F1 mice.
@ast
Anti-dsDNA antibodies promote ...... n autoimmune (NZBxNZW)F1 mice.
@en
Anti-dsDNA antibodies promote ...... n autoimmune (NZBxNZW)F1 mice.
@nl
prefLabel
Anti-dsDNA antibodies promote ...... n autoimmune (NZBxNZW)F1 mice.
@ast
Anti-dsDNA antibodies promote ...... n autoimmune (NZBxNZW)F1 mice.
@en
Anti-dsDNA antibodies promote ...... n autoimmune (NZBxNZW)F1 mice.
@nl
P2093
P2860
P1433
P1476
Anti-dsDNA antibodies promote ...... n autoimmune (NZBxNZW)F1 mice.
@en
P2093
Annica Hedberg
Chris Fenton
Elin Synnøve Mortensen
Natalya Seredkina
Silje Fismen
P2860
P356
10.1371/JOURNAL.PONE.0008474
P407
P577
2009-12-29T00:00:00Z