Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.
about
Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccinationIRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humansUNC93B1 is essential for TLR11 activation and IL-12-dependent host resistance to Toxoplasma gondiiMicrobe sensing, positive feedback loops, and the pathogenesis of inflammatory diseasesTrex1 prevents cell-intrinsic initiation of autoimmunityTargeted therapeutics in SLE: emerging strategies to modulate the interferon pathwayBreakdown of Immune Tolerance in Systemic Lupus Erythematosus by Dendritic CellsAn unexpected role for RNA-sensing toll-like receptors in a murine model of DNA accrualAge-Associated B Cells: A T-bet-Dependent Effector with Roles in Protective and Pathogenic ImmunityDefects in Germinal Center Selection in SLELinking susceptibility genes and pathogenesis mechanisms using mouse models of systemic lupus erythematosusImmune-regulatory mechanisms in systemic autoimmune and rheumatic diseasesContribution of Toll-like receptor signaling to germinal center antibody responsesToll-like receptors in systemic lupus erythematosus: potential targets for therapeutic interventionB cells take the front seat: dysregulated B cell signals orchestrate loss of tolerance and autoantibody productionIntracellular nucleic acid sensors and autoimmunityRNA mediated Toll-like receptor stimulation in health and diseaseThe enemy within: endogenous retroelements and autoimmune diseaseAutoantibodies in systemic autoimmune diseases: specificity and pathogenicityToll-like receptors in the pathogenesis of autoimmune diseases: recent and emerging translational developmentsDanger Signals and Graft-versus-host Disease: Current Understanding and Future PerspectivesSexual dimorphism in autoimmunityContribution of dendritic cells to the autoimmune pathology of systemic lupus erythematosusNucleic Acid-Sensing Receptors: Rheostats of Autoimmunity and AutoinflammationMechanisms of autoantibody production in systemic lupus erythematosusThe Role of Anti-DNA Antibodies in the Development of Lupus Nephritis: A Complementary, or Alternative, Viewpoint?The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunityTLR8 deficiency leads to autoimmunity in miceApoptotic cell responses in the splenic marginal zone: a paradigm for immunologic reactions to apoptotic antigens with implications for autoimmunityNucleic acid scavenging polymers inhibit extracellular DNA-mediated innate immune activation without inhibiting anti-viral responsesGuanine-modified inhibitory oligonucleotides efficiently impair TLR7- and TLR9-mediated immune responses of human immune cellsEstrogen receptor alpha modulates Toll-like receptor signaling in murine lupusRole for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/AktGenetic complementation results in augmented autoantibody responses to lupus-associated antigens.Endocytic sequestration of the B cell antigen receptor and toll-like receptor 9 in anergic cells.CD2 distinguishes two subsets of human plasmacytoid dendritic cells with distinct phenotype and functions.Impaired autoimmune T helper 17 cell responses following DNA vaccination against rat experimental autoimmune encephalomyelitis.The largely normal response to Toll-like receptor 7 and 9 stimulation and the enhanced expression of SIGIRR by B cells in systemic lupus erythematosus.Comparison of human B cell activation by TLR7 and TLR9 agonists.Solving the genetic puzzle of systemic lupus erythematosus.
P2860
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P2860
Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Toll-like receptor 7 and TLR9 ...... es in a murine model of lupus.
@ast
Toll-like receptor 7 and TLR9 ...... es in a murine model of lupus.
@en
Toll-like receptor 7 and TLR9 ...... es in a murine model of lupus.
@nl
type
label
Toll-like receptor 7 and TLR9 ...... es in a murine model of lupus.
@ast
Toll-like receptor 7 and TLR9 ...... es in a murine model of lupus.
@en
Toll-like receptor 7 and TLR9 ...... es in a murine model of lupus.
@nl
prefLabel
Toll-like receptor 7 and TLR9 ...... es in a murine model of lupus.
@ast
Toll-like receptor 7 and TLR9 ...... es in a murine model of lupus.
@en
Toll-like receptor 7 and TLR9 ...... es in a murine model of lupus.
@nl
P2093
P1433
P1476
Toll-like receptor 7 and TLR9 ...... les in a murine model of lupus
@en
P2093
Jonathan Shupe
Mark J Shlomchik
Michael Kashgarian
Richard A Flavell
Sean R Christensen
P304
P356
10.1016/J.IMMUNI.2006.07.013
P407
P577
2006-09-01T00:00:00Z