17-AAG induces cytoplasmic alpha-synuclein aggregate clearance by induction of autophagy
about
PINK1 cleavage at position A103 by the mitochondrial protease PARL.Autophagy in ageing and ageing-associated diseasesDirect and/or Indirect Roles for SUMO in Modulating Alpha-Synuclein ToxicityMolecular chaperones and co-chaperones in Parkinson diseaseProtein degradation pathways in Parkinson's disease: curse or blessingNiclosamide prevents the formation of large ubiquitin-containing aggregates caused by proteasome inhibitionDynamic impacts of the inhibition of the molecular chaperone Hsp90 on the T-cell proteome have implications for anti-cancer therapyRevisiting and revising the purinosomeMolecular chaperones and protein folding as therapeutic targets in Parkinson's disease and other synucleinopathiesHsp70 and its molecular role in nervous system diseasesThe aggregation and neurotoxicity of TDP-43 and its ALS-associated 25 kDa fragment are differentially affected by molecular chaperones in Drosophila.Hsp70- and Hsp90-mediated proteasomal degradation underlies TPI sugarkill pathogenesis in Drosophila.Heat shock protein 90-mediated inactivation of nuclear factor-κB switches autophagy to apoptosis through becn1 transcriptional inhibition in selenite-induced NB4 cells.Molecular chaperones in Parkinson's disease--present and futureStimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy.A Novel Hsp90 Inhibitor Activates Compensatory Heat Shock Protein Responses and Autophagy and Alleviates Mutant A53T α-Synuclein Toxicity.Chronic treatment with 17-DMAG improves balance and coordination in a new mouse model of Machado-Joseph disease.Molecular chaperones and associated cellular clearance mechanisms against toxic protein conformers in Parkinson's disease.Tumor necrosis factor receptor-associated periodic syndrome as a model linking autophagy and inflammation in protein aggregation diseases.Barcoding heat shock proteins to human diseases: looking beyond the heat shock responseBehind the curtain of tauopathy: a show of multiple players orchestrating tau toxicity.Mitochondrial impairment and oxidative stress compromise autophagosomal degradation of α-synuclein in oligodendroglial cells.Inhibition of UCH-L1 in oligodendroglial cells results in microtubule stabilization and prevents α-synuclein aggregate formation by activating the autophagic pathway: implications for multiple system atrophy.Oxidative stress promotes uptake, accumulation, and oligomerization of extracellular α-synuclein in oligodendrocytes.Influence of Hsp90 and HDAC inhibition and tubulin acetylation on perinuclear protein aggregation in human retinal pigment epithelial cells.Identification of an HSP90 modulated multi-step process for ERBB2 degradation in breast cancer cells.Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention.Aggregate clearance of α-synuclein in Saccharomyces cerevisiae depends more on autophagosome and vacuole function than on the proteasome.Involvement of macroautophagy in multiple system atrophy and protein aggregate formation in oligodendrocytes.Activation of autophagy by rapamycin does not protect oligodendrocytes against protein aggregate formation and cell death induced by proteasomal inhibition.Clusterin protects neurons against intracellular proteotoxicity.Proteomic interrogation of HSP90 and insights for medical research.
P2860
Q24313472-322E222F-9B09-4FD2-98DB-A1514FB4E49CQ24629560-5A2FF2F5-6ED7-49C1-9B2E-5568D8F467B2Q26799306-823CC409-A1F9-43D9-B9BE-1D4928B57FBEQ26828834-FFCBCEF0-B8EA-4392-BFE3-077BCA079214Q27026029-866C43D5-31ED-4D19-8DCC-74C985A48CAEQ27314985-4802FA21-A1E6-45C6-8B83-D6817CB56D66Q28535465-269BA4CB-D301-4628-AFB6-721EAF7093F5Q28656168-C9E55F95-B35D-4042-A114-CE16FEA04BADQ33715640-F04274FC-129E-4811-BEA0-EF84B823439AQ34170760-B1B3D595-49C4-479C-8CB6-8BA2DD665882Q34182046-D91766F3-BF9E-4CE8-9559-0721FB07B889Q34204041-B1976AB4-26BA-441C-BF43-943C40F8BB45Q34803115-142F67FF-CFFA-4C2C-913E-CCF732519D62Q35688796-75FFE317-8493-4493-9730-4127E94DC554Q36054214-870A1E4A-93BD-43EA-AC15-739783A677C4Q36316808-5BBBE007-9041-476A-AA5B-76E10E42241AQ37717405-36E9D93F-0157-4254-8E18-6B30ED2D215BQ37853789-9F868FAA-4173-490A-ABC8-29CF06D26947Q38202563-94A80BD1-04F6-441C-BBED-DE83B8F94C24Q38203487-589DD127-7427-4CEE-BD36-342827F902C7Q38592451-33028BFF-045F-4A58-8CEB-3091ED399649Q38849169-2F8F33A7-1A6B-433D-B38C-B79A1A788BD5Q38872092-03920E36-DF81-41BD-993F-B0B92D9301BEQ39064365-5199E794-BECC-47D3-B4C5-60A49E5B6F48Q39638984-0704AFF2-FB25-43F3-9E8F-B5E8AADA698BQ41773399-DE7B0819-5160-4C99-A3A2-887035274B99Q41786144-FC393670-90AD-4A16-B505-3FCA90C934C5Q42322220-BE6655B0-0E1E-430F-923D-EC50BF88C1C5Q44539585-93F5DD4A-8026-490B-B09E-BE2982EA8313Q45352305-79DB8B30-4F7E-40DF-9379-EC2092DDB3BBQ47101840-C1769BA5-1382-4334-B698-BAFAE81A52B5Q47678542-42F63BDB-631F-4B73-BA77-5BC1DD00E892
P2860
17-AAG induces cytoplasmic alpha-synuclein aggregate clearance by induction of autophagy
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
17-AAG induces cytoplasmic alpha-synuclein aggregate clearance by induction of autophagy
@ast
17-AAG induces cytoplasmic alpha-synuclein aggregate clearance by induction of autophagy
@en
17-AAG induces cytoplasmic alpha-synuclein aggregate clearance by induction of autophagy.
@nl
type
label
17-AAG induces cytoplasmic alpha-synuclein aggregate clearance by induction of autophagy
@ast
17-AAG induces cytoplasmic alpha-synuclein aggregate clearance by induction of autophagy
@en
17-AAG induces cytoplasmic alpha-synuclein aggregate clearance by induction of autophagy.
@nl
prefLabel
17-AAG induces cytoplasmic alpha-synuclein aggregate clearance by induction of autophagy
@ast
17-AAG induces cytoplasmic alpha-synuclein aggregate clearance by induction of autophagy
@en
17-AAG induces cytoplasmic alpha-synuclein aggregate clearance by induction of autophagy.
@nl
P2093
P2860
P1433
P1476
17-AAG induces cytoplasmic alpha-synuclein aggregate clearance by induction of autophagy
@en
P2093
Lisa Schwarz
Michael Riedel
Sebastian Schmitt
P2860
P356
10.1371/JOURNAL.PONE.0008753
P407
P577
2010-01-18T00:00:00Z