Chronic treatment with 17-DMAG improves balance and coordination in a new mouse model of Machado-Joseph disease.
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Autophagy and neurodegenerationAutophagy in polyglutamine disease: Imposing order on disorder or contributing to the chaos?Selective targeting of the stress chaperome as a therapeutic strategyLimited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph DiseaseSerotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease.The biology of proteostasis in aging and disease.Dominant negative effect of polyglutamine expansion perturbs normal function of ataxin-3 in neuronal cells.Inactivation of PNKP by mutant ATXN3 triggers apoptosis by activating the DNA damage-response pathway in SCA3The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis.Absence of Tau triggers age-dependent sciatic nerve morphofunctional deficits and motor impairmentA longitudinal investigation into cognition and disease progression in spinocerebellar ataxia types 1, 2, 3, 6, and 7Autophagy Promoted the Degradation of Mutant ATXN3 in Neurally Differentiated Spinocerebellar Ataxia-3 Human Induced Pluripotent Stem Cells.The Ubiquitination, Disaggregation and Proteasomal Degradation Machineries in Polyglutamine DiseaseFrom pathways to targets: understanding the mechanisms behind polyglutamine disease.Molecular chaperones and neuronal proteostasis.High-mobility group box 1 regulates cytoprotective autophagy in a mouse spermatocyte cell line (GC-2spd) exposed to cadmium.Possible Function of Molecular Chaperones in Diseases Caused by Propagating Amyloid Aggregates.Discovery of Therapeutic Approaches for Polyglutamine Diseases: A Summary of Recent Efforts.Altered striatal endocannabinoid signaling in a transgenic mouse model of spinocerebellar ataxia type-3.Modulation of Molecular Chaperones in Huntington's Disease and Other Polyglutamine Disorders.Selective rescue of heightened anxiety but not gait ataxia in a premutation 90CGG mouse model of Fragile X-associated tremor/ataxia syndrome.Unbiased screen identifies aripiprazole as a modulator of abundance of the polyglutamine disease protein, ataxin-3.Lithium chloride therapy fails to improve motor function in a transgenic mouse model of Machado-Joseph disease.Repeated Mesenchymal Stromal Cell Treatment Sustainably Alleviates Machado-Joseph Disease
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P2860
Chronic treatment with 17-DMAG improves balance and coordination in a new mouse model of Machado-Joseph disease.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2014
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Chronic treatment with 17-DMAG ...... del of Machado-Joseph disease.
@en
Chronic treatment with 17-DMAG ...... del of Machado-Joseph disease.
@nl
type
label
Chronic treatment with 17-DMAG ...... del of Machado-Joseph disease.
@en
Chronic treatment with 17-DMAG ...... del of Machado-Joseph disease.
@nl
prefLabel
Chronic treatment with 17-DMAG ...... del of Machado-Joseph disease.
@en
Chronic treatment with 17-DMAG ...... del of Machado-Joseph disease.
@nl
P2093
P2860
P50
P1433
P1476
Chronic treatment with 17-DMAG ...... del of Machado-Joseph disease.
@en
P2093
Andreia Neves-Carvalho
Kenneth Thirstrup
Marina Amorim
Pedro Oliveira
P2860
P2888
P304
P356
10.1007/S13311-013-0255-9
P50
P577
2014-04-01T00:00:00Z