The Caenorhabditis elegans Elongator complex regulates neuronal alpha-tubulin acetylation. - Wikidata - wikimedia - TriplyDB

The Caenorhabditis elegans Elongator complex regulates neuronal alpha-tubulin acetylation.

The Caenorhabditis elegans Elongator complex regulates neuronal alpha-tubulin acetylation.

http://www.wikidata.org/entity/Q33526997

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Mice lacking α-tubulin acetyltransferase 1 are viable but display α-tubulin acetylation deficiency and dentate gyrus distortion DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator MEC-17 is an alpha-tubulin acetyltransferase Lysine post-translational modifications and the cytoskeleton Crystal Structure of Elongator Subcomplex Elp4-6 Phosphorylation of Elp1 by Hrr25 is required for elongator-dependent tRNA modification in yeast.The major alpha-tubulin K40 acetyltransferase alphaTAT1 promotes rapid ciliogenesis and efficient mechanosensation The Many Faces of Elongator in Neurodevelopment and Disease The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS Familial Dysautonomia (FD) Human Embryonic Stem Cell Derived PNS Neurons Reveal that Synaptic Vesicular and Neuronal Transport Genes Are Directly or Indirectly Affected by IKBKAP Downregulation Elongator function in tRNA wobble uridine modification is conserved between yeast and plants.Α-tubulin K40 acetylation is required for contact inhibition of proliferation and cell-substrate adhesion Receptors and other signaling proteins required for serotonin control of locomotion in Caenorhabditis elegans.A neuron autonomous role for the familial dysautonomia gene ELP1 in sympathetic and sensory target tissue innervation.Olfactory stem cells, a new cellular model for studying molecular mechanisms underlying familial dysautonomia Effects of IKAP/hELP1 deficiency on gene expression in differentiating neuroblastoma cells: implications for familial dysautonomia.Elongator complex influences telomeric gene silencing and DNA damage response by its role in wobble uridine tRNA modification.IKAP/Elp1 is required in vivo for neurogenesis and neuronal survival, but not for neural crest migration.Post-translational modifications of microtubules.Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions.Tubulin acetyltransferase discovered: ciliary role in the ancestral eukaryote expanded to neurons in metazoans Tubulin acetylation: responsible enzymes, biological functions and human diseases.Ikbkap/Elp1 deficiency causes male infertility by disrupting meiotic progression Role of elongator subunit Elp3 in Drosophila melanogaster larval development and immunity.Silencing SlELP2L, a tomato Elongator complex protein 2-like gene, inhibits leaf growth, accelerates leaf, sepal senescence, and produces dark-green fruit The balance between cytoplasmic and nuclear CaM kinase-1 signaling controls the operating range of noxious heat avoidance.Depletion of the IKBKAP ortholog in zebrafish leads to hirschsprung disease-like phenotype.Prognostic significance of elongator protein 3 expression in endometrioid adenocarcinoma.Phosphatidylserine Ameliorates Neurodegenerative Symptoms and Enhances Axonal Transport in a Mouse Model of Familial Dysautonomia.New HDAC6-mediated deacetylation sites of tubulin in the mouse brain identified by quantitative mass spectrometry BRCA1/2 mutations perturb telomere biology: characterization of structural and functional abnormalities in vitro and in vivo Elongator: transcriptional or translational regulator?EWSR1 regulates mitosis by dynamically influencing microtubule acetylation.Familial dysautonomia model reveals Ikbkap deletion causes apoptosis of Pax3+ progenitors and peripheral neurons.The tale of protein lysine acetylation in the cytoplasm.Elongator: an ancestral complex driving transcription and migration through protein acetylation Elongator, a conserved complex required for wobble uridine modifications in eukaryotes.Analysis of the amyloid precursor protein role in neuritogenesis reveals a biphasic SH-SY5Y neuronal cell differentiation model.Molecular profiling of functional interactions between pre-osteoblastic and breast carcinoma cells.Animal and cellular models of familial dysautonomia.

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The Caenorhabditis elegans Elongator complex regulates neuronal alpha-tubulin acetylation.

http://www.wikidata.org/entity/Q33526997

description

2010 nî lūn-bûn

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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2010 թվականի հունվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

The Caenorhabditis elegans Elo ...... nal alpha-tubulin acetylation.

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The Caenorhabditis elegans Elo ...... nal alpha-tubulin acetylation.

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The Caenorhabditis elegans Elo ...... nal alpha-tubulin acetylation.

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The Caenorhabditis elegans Elo ...... nal alpha-tubulin acetylation.

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The Caenorhabditis elegans Elo ...... nal alpha-tubulin acetylation.

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The Caenorhabditis elegans Elo ...... nal alpha-tubulin acetylation.

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The Caenorhabditis elegans Elo ...... nal alpha-tubulin acetylation.

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The Caenorhabditis elegans Elo ...... nal alpha-tubulin acetylation.

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The Caenorhabditis elegans Elo ...... nal alpha-tubulin acetylation.

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JOURNAL.PGEN.1000820

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The Caenorhabditis elegans Elo ...... nal alpha-tubulin acetylation.

@en

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Dai Mitsushima

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Giuseppe Cassata

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Holger Klöss

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Jachen A Solinger

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Roberta Paolinelli

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Stefano Marchesi

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Stephen R Stürzenbaum

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Ursula Sauder

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P2860

Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts

Purification and characterization of the human elongator complex

Human Elongator facilitates RNA polymerase II transcription through chromatin

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

HDAC6 is a microtubule-associated deacetylase

The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin

Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo.

Tissue-specific reduction in splicing efficiency of IKBKAP due to the major mutation associated with familial dysautonomia.

Tissue-specific expression of a splicing mutation in the IKBKAP gene causes familial dysautonomia

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e1000820

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scholarly article

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10.1371/JOURNAL.PGEN.1000820

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1

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6

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Francesco Berlanda Scorza

Fabrizio Capuani

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2010-01-22T00:00:00Z

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41166601

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20107598

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Caenorhabditis elegans

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2809763

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