BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control. - Wikidata - wikimedia - TriplyDB

BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control.

BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control.

http://www.wikidata.org/entity/Q33531604

about

Chk1 suppressed cell death Human single-stranded DNA binding proteins are essential for maintaining genomic stability BRCT domains: easy as one, two, three Getting Ready for the Dance: FANCJ Irons Out DNA Wrinkles Interplay between Fanconi anemia and homologous recombination pathways in genome integrity Fanconi anemia and the cell cycle: new perspectives on aneuploidy TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis Structure and function of the Rad9-binding region of the DNA-damage checkpoint adaptor TopBP1 Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control Structural Insights into Recognition of MDC1 by TopBP1 in DNA Replication Checkpoint Control Phosphorylation-Dependent Assembly and Coordination of the DNA Damage Checkpoint Apparatus by Rad4TopBP1 FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice Homologs of breast cancer genes in plants Expanded roles of the Fanconi anemia pathway in preserving genomic stability Mechanistic and biological aspects of helicase action on damaged DNA.The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response Insight into the roles of helicase motif Ia by characterizing Fanconi anemia group J protein (FANCJ) patient mutations Interactive Roles of DNA Helicases and Translocases with the Single-Stranded DNA Binding Protein RPA in Nucleic Acid Metabolism.ATR autophosphorylation as a molecular switch for checkpoint activation.A two-phase case-control study for colorectal cancer genetic susceptibility: candidate genes from chromosomal regions 9q22 and 3q22.The Fanconi anemia proteins FANCD2 and FANCJ interact and regulate each other's chromatin localization.FANCJ/BACH1 acetylation at lysine 1249 regulates the DNA damage response Molecular and cellular functions of the FANCJ DNA helicase defective in cancer and in Fanconi anemia Helicase-inactivating mutations as a basis for dominant negative phenotypes.SIRT1 deacetylates TopBP1 and modulates intra-S-phase checkpoint and DNA replication origin firing PTIP associates with Artemis to dictate DNA repair pathway choice.MDC1 collaborates with TopBP1 in DNA replication checkpoint control.Hereditary breast cancer and the BRCA1-associated FANCJ/BACH1/BRIP1.TopBP1 interacts with BLM to maintain genome stability but is dispensable for preventing BLM degradation.TOPBP1 recruits TOP2A to ultra-fine anaphase bridges to aid in their resolution.BRCA1 is required for postreplication repair after UV-induced DNA damage TopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73.Fanconi anemia and Bloom's syndrome crosstalk through FANCJ-BLM helicase interaction.Rescue of replication failure by Fanconi anaemia proteins.Protein degradation pathways regulate the functions of helicases in the DNA damage response and maintenance of genomic stability BRCA1 tumor suppressor network: focusing on its tail.hMSH5 Facilitates the Repair of Camptothecin-induced Double-strand Breaks through an Interaction with FANCJ.DNA helicases involved in DNA repair and their roles in cancer And-1 coordinates with Claspin for efficient Chk1 activation in response to replication stress Direct Binding to Replication Protein A (RPA)-coated Single-stranded DNA Allows Recruitment of the ATR Activator TopBP1 to Sites of DNA Damage.

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BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control.

http://www.wikidata.org/entity/Q33531604

description

2010 nî lūn-bûn

@nan

2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

BACH1/FANCJ acts with TopBP1 a ...... eplication checkpoint control.

@ast

BACH1/FANCJ acts with TopBP1 a ...... eplication checkpoint control.

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BACH1/FANCJ acts with TopBP1 a ...... eplication checkpoint control.

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type

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BACH1/FANCJ acts with TopBP1 a ...... eplication checkpoint control.

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BACH1/FANCJ acts with TopBP1 a ...... eplication checkpoint control.

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BACH1/FANCJ acts with TopBP1 a ...... eplication checkpoint control.

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prefLabel

BACH1/FANCJ acts with TopBP1 a ...... eplication checkpoint control.

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BACH1/FANCJ acts with TopBP1 a ...... eplication checkpoint control.

@en

BACH1/FANCJ acts with TopBP1 a ...... eplication checkpoint control.

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J.MOLCEL.2010.01.002

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BACH1/FANCJ acts with TopBP1 a ...... eplication checkpoint control.

@en

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Charles Chung Yun Leung

http://www.w3.org/2001/XMLSchema#string

J N Mark Glover

http://www.w3.org/2001/XMLSchema#string

Ja-Eun Kim

http://www.w3.org/2001/XMLSchema#string

Junjie Chen

http://www.w3.org/2001/XMLSchema#string

Zihua Gong

http://www.w3.org/2001/XMLSchema#string

P2860

BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function

The BRCT domain is a phospho-protein binding domain

DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains

A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival.

Mechanisms to control rereplication and implications for cancer.

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast.

Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast.

DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae.

BRCT domain-containing protein TopBP1 functions in DNA replication and damage response

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438-446

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scholarly article

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10.1016/J.MOLCEL.2010.01.002

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3

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37

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2010-02-01T00:00:00Z

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41451359

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20159562

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3695484

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