BRCA1 is required for postreplication repair after UV-induced DNA damage
about
Targeting DNA Replication Stress for Cancer TherapyGenomic scars as biomarkers of homologous recombination deficiency and drug response in breast and ovarian cancersUSP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responsesBRCA1 deficiency exacerbates estrogen-induced DNA damage and genomic instabilityBRCA1 controls homologous recombination at Tus/Ter-stalled mammalian replication forksChronic treatment with cisplatin induces replication-dependent sister chromatid recombination to confer cisplatin-resistant phenotype in nasopharyngeal carcinoma.BRCA1 pathway function in basal-like breast cancer cells.Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damageRepair of naturally occurring mismatches can induce mutations in flanking DNA.Constitutional and somatic deletions of the Williams-Beuren syndrome critical region in non-Hodgkin lymphomaThe chromatin remodeling protein BRG1 modulates BRCA1 response to UV irradiation by regulating ATR/ATM activation.FANC pathway promotes UV-induced stalled replication forks recovery by acting both upstream and downstream Polη and Rev1.BRCA1 haploinsufficiency for replication stress suppression in primary cellsPARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination-mediated DNA repair.Tumor mutation burden forecasts outcome in ovarian cancer with BRCA1 or BRCA2 mutations.BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair.Key mediators of somatic ATR signaling localize to unpaired chromosomes in spermatocytes.BRCA1 regulates PIG3-mediated apoptosis in a p53-dependent manner.Oncogenic BRAF(V600E) Induces Clastogenesis and UVB HypersensitivityBRCA1 tumor suppressor network: focusing on its tail.Repair of transposable phage Mu DNA insertions begins only when the E. coli replisome collides with the transpososomeA porcine model system of BRCA1 driven breast cancer.Mechanism of release and fate of excised oligonucleotides during nucleotide excision repairReplication fork stability confers chemoresistance in BRCA-deficient cellsMechanisms of BRCA1 tumor suppressionAugmented generation of protein fragments during wakefulness as the molecular cause of sleep: a hypothesis.BRCA1 inhibits AR-mediated proliferation of breast cancer cells through the activation of SIRT1The role of BRCA1 in homologous recombination repair in response to replication stress: significance in tumorigenesis and cancer therapyPARI overexpression promotes genomic instability and pancreatic tumorigenesis.BRCA1 in the DNA damage response and at telomeresFANCJ at the FORK.RING domain-deficient BRCA1 promotes PARP inhibitor and platinum resistance.Spatial separation of replisome arrest sites influences homologous recombination quality at a Tus/Ter-mediated replication fork barrier.BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells.Physiological modulation of endogenous BRCA1 p220 abundance suppresses DNA damage during the cell cycleLoss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions.BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity.Loss of Caenorhabditis elegans BRCA1 promotes genome stability during replication in smc-5 mutantsLinks between genome integrity and BRCA1 tumor suppression.Proteomic identification of a direct role for cyclin d1 in DNA damage repair.
P2860
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P2860
BRCA1 is required for postreplication repair after UV-induced DNA damage
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2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
BRCA1 is required for postreplication repair after UV-induced DNA damage
@ast
BRCA1 is required for postreplication repair after UV-induced DNA damage
@en
type
label
BRCA1 is required for postreplication repair after UV-induced DNA damage
@ast
BRCA1 is required for postreplication repair after UV-induced DNA damage
@en
prefLabel
BRCA1 is required for postreplication repair after UV-induced DNA damage
@ast
BRCA1 is required for postreplication repair after UV-induced DNA damage
@en
P2093
P2860
P1433
P1476
BRCA1 is required for postreplication repair after UV-induced DNA damage
@en
P2093
David M Livingston
Guillaume O Adelmant
Jarrod A Marto
Jean Feunteun
Jenna Nguyen
Ralph Scully
Sarah J Hill
Shailja Pathania
P2860
P304
P356
10.1016/J.MOLCEL.2011.09.002
P577
2011-09-29T00:00:00Z