Abnormalities of cell packing density and dendritic complexity in the MeCP2 A140V mouse model of Rett syndrome/X-linked mental retardation
about
Recent advances in understanding synaptic abnormalities in Rett syndromeDaily rhythmic behaviors and thermoregulatory patterns are disrupted in adult female MeCP2-deficient miceRett syndrome: disruption of epigenetic control of postnatal neurological functionsA new synaptic player leading to autism risk: Met receptor tyrosine kinaseEssential Roles for ARID1B in Dendritic Arborization and Spine Morphology of Developing Pyramidal NeuronsMeCP2 deficiency results in robust Rett-like behavioural and motor deficits in male and female ratsStem cells and modeling of autism spectrum disorders.Female Mecp2(+/-) mice display robust behavioral deficits on two different genetic backgrounds providing a framework for pre-clinical studies.Beyond Widespread Mecp2 Deletions to Model Rett Syndrome: Conditional Spatio-Temporal Knockout, Single-Point Mutations and Transgenic Rescue MiceRett syndrome mutation MeCP2 T158A disrupts DNA binding, protein stability and ERP responsesMorphological and functional reversal of phenotypes in a mouse model of Rett syndrome.Preclinical research in Rett syndrome: setting the foundation for translational success.Twenty-four hour quantitative-EEG and in-vivo glutamate biosensor detects activity and circadian rhythm dependent biomarkers of pathogenesis in Mecp2 null mice.Transcriptome analysis of microglia in a mouse model of Rett syndrome: differential expression of genes associated with microglia/macrophage activation and cellular stressTemporal and regional alterations in NMDA receptor expression in Mecp2-null mice.Drosophila as a model for MECP2 gain of function in neurons.MeCP2 mutation results in compartment-specific reductions in dendritic branching and spine density in layer 5 motor cortical neurons of YFP-H mice.Experimental models of Rett syndrome based on Mecp2 dysfunction.Complexities of Rett syndrome and MeCP2Aberrant dendritic excitability: a common pathophysiology in CNS disorders affecting memory?Neuronal morphology in MeCP2 mouse models is intrinsically variable and depends on age, cell type, and Mecp2 mutation.Apoptotic Activity of MeCP2 Is Enhanced by C-Terminal Truncating Mutations.A/T Run Geometry of B-form DNA Is Independent of Bound Methyl-CpG Binding Domain, Cytosine Methylation and Flanking Sequence.MicroRNA function is required for neurite outgrowth of mature neurons in the mouse postnatal cerebral cortex.Epigenetics, autism spectrum, and neurodevelopmental disorders.Reduced neuronal size and mTOR pathway activity in the Mecp2 A140V Rett syndrome mouse modelLoss of MeCP2 disrupts cell autonomous and autocrine BDNF signaling in mouse glutamatergic neuronsMeCP2-Related Diseases and Animal Models.Genetic diseases: congenital central hypoventilation, Rett, and Prader-Willi syndromes.Translating human genetics into mouse: the impact of ultra-rapid in vivo genome editing.Rett syndrome and MeCP2.Genetic alterations of DNA methylation machinery in human diseases.Temporal- and Location-Specific Alterations of the GABA Recycling System in Mecp2 KO Mouse Brains.Autism spectrum disorder: neuropathology and animal models.MECP2 impairs neuronal structure by regulating KIBRA.RNA sequencing and proteomics approaches reveal novel deficits in the cortex of Mecp2-deficient mice, a model for Rett syndrome.Adolescent onset cognitive regression and neuropsychiatric symptoms associated with the A140V MECP2 mutation.[Epigenetic regulation in neuronal differentiation and brain function].Early motor phenotype detection in a female mouse model of Rett syndrome is improved by cross-fostering.ANKRD11 associated with intellectual disability and autism regulates dendrite differentiation via the BDNF/TrkB signaling pathway.
P2860
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P2860
Abnormalities of cell packing density and dendritic complexity in the MeCP2 A140V mouse model of Rett syndrome/X-linked mental retardation
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Abnormalities of cell packing ...... me/X-linked mental retardation
@ast
Abnormalities of cell packing ...... me/X-linked mental retardation
@en
Abnormalities of cell packing ...... e/X-linked mental retardation.
@nl
type
label
Abnormalities of cell packing ...... me/X-linked mental retardation
@ast
Abnormalities of cell packing ...... me/X-linked mental retardation
@en
Abnormalities of cell packing ...... e/X-linked mental retardation.
@nl
prefLabel
Abnormalities of cell packing ...... me/X-linked mental retardation
@ast
Abnormalities of cell packing ...... me/X-linked mental retardation
@en
Abnormalities of cell packing ...... e/X-linked mental retardation.
@nl
P2093
P2860
P356
P1433
P1476
Abnormalities of cell packing ...... me/X-linked mental retardation
@en
P2093
Garilyn M Jentarra
Nishit Srivastava
Sakkubai Naidu
Shannon L Olfers
Stephen G Rice
P2860
P2888
P356
10.1186/1471-2202-11-19
P577
2010-02-17T00:00:00Z
P5875
P6179
1045810959