How might replicative senescence contribute to human ageing?
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Angiotensin II requires zinc and downregulation of the zinc transporters ZnT3 and ZnT10 to induce senescence of vascular smooth muscle cellsVitamin D3 up-regulated protein 1(VDUP1) is regulated by FOXO3A and miR-17-5p at the transcriptional and post-transcriptional levels, respectively, in senescent fibroblastsHDACs and the senescent phenotype of WI-38 cells.Circadian clock protein BMAL1 regulates cellular senescence in vivoHutchinson-Guilford progeria syndromeSilencing of the Menkes copper-transporting ATPase (Atp7a) gene increases cyclin D1 protein expression and impairs proliferation of rat intestinal epithelial (IEC-6) cells.Endothelial progenitor cells dysfunction and senescence: contribution to oxidative stress.Notch signaling regulates the lifespan of vascular endothelial cells via a p16-dependent pathwayPreterm infants have significantly longer telomeres than their term born counterpartsMicrowave-assisted synthesis of a pyrazolyl ketone library for evaluation as p38 MAPK inhibitors in Werner syndrome cells.Aging and animal models of systemic insult: trauma, burn, and sepsis.Association between telomere length, specific causes of death, and years of healthy life in health, aging, and body composition, a population-based cohort study.Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci.Telomere length is paternally inherited and is associated with parental lifespan.Feasibility of human telomerase reverse transcriptase mRNA expression in individual blastomeres as an indicator of early embryo developmentAdult stem cell maintenance and tissue regeneration in the ageing context: the role for A-type lamins as intrinsic modulators of ageing in adult stem cells and their niches.Physiological and pathological consequences of cellular senescence.Somatic stem cell aging and malignant transformation--impact on therapeutic application.The mitogen-inducible gene-6 is involved in regulation of cellular senescence in normal diploid fibroblasts.Akt negatively regulates the in vitro lifespan of human endothelial cells via a p53/p21-dependent pathwayMelatonin suppresses doxorubicin-induced premature senescence of A549 lung cancer cells by ameliorating mitochondrial dysfunction.Synthesis of the highly selective p38 MAPK inhibitor UR-13756 for possible therapeutic use in Werner syndrome.Gram-scale synthesis of the p38α MAPK-inhibitor VX-745 for preclinical studies into Werner syndrome.Senescence in the aging process.Replication fork regression in vitro by the Werner syndrome protein (WRN): holliday junction formation, the effect of leading arm structure and a potential role for WRN exonuclease activity.Replicative senescence of vascular smooth muscle cells enhances the calcification through initiating the osteoblastic transition.Increased autophagic activity in senescent human dental pulp cells.Explaining differences in the lifespan and replicative capacity of cells: a general model and comparative analysis of vertebrates.Increased oral fibroblast lifespan is telomerase-independent.NADPH Oxidases and Mitochondria in Vascular Senescence.
P2860
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P2860
How might replicative senescence contribute to human ageing?
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
How might replicative senescence contribute to human ageing?
@ast
How might replicative senescence contribute to human ageing?
@en
How might replicative senescence contribute to human ageing?
@nl
type
label
How might replicative senescence contribute to human ageing?
@ast
How might replicative senescence contribute to human ageing?
@en
How might replicative senescence contribute to human ageing?
@nl
prefLabel
How might replicative senescence contribute to human ageing?
@ast
How might replicative senescence contribute to human ageing?
@en
How might replicative senescence contribute to human ageing?
@nl
P1433
P1476
How might replicative senescence contribute to human ageing?
@en
P2093
Faragher RG
P304
P356
10.1002/(SICI)1521-1878(199812)20:12<985::AID-BIES4>3.3.CO;2-1
P407
P577
1998-12-01T00:00:00Z