Salinomycin overcomes ABC transporter-mediated multidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cells.
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Salinomycin as a drug for targeting human cancer stem cellsSalinomycin: a novel anti-cancer agent with known anti-coccidial activitiesSalinomycin induces autophagy in colon and breast cancer cells with concomitant generation of reactive oxygen speciesSalinomycin activates AMP-activated protein kinase-dependent autophagy in cultured osteoblastoma cells: a negative regulator against cell apoptosisSalinomycin potentiates the cytotoxic effects of TRAIL on glioblastoma cell linesInhibition of autophagic flux by salinomycin results in anti-cancer effect in hepatocellular carcinoma cellsAntiCD3Fv fused to human interleukin-3 deletion variant redirected T cells against human acute myeloid leukemic stem cellsSynergistic induction of apoptosis by salinomycin and gefitinib through lysosomal and mitochondrial dependent pathway overcomes gefitinib resistance in colorectal cancer.ABC transporters in CSCs membranes as a novel target for treating tumor relapse.Sensitization of cancer cells through reduction of total Akt and downregulation of salinomycin-induced pAkt, pGSk3β, pTSC2, and p4EBP1 by cotreatment with MK-2206.A late-stage intermediate in salinomycin biosynthesis is revealed by specific mutation in the biosynthetic gene cluster.Targeting miRNAs involved in cancer stem cell and EMT regulation: An emerging concept in overcoming drug resistance.Impact of Salinomycin on human cholangiocarcinoma: induction of apoptosis and impairment of tumor cell proliferation in vitroSalinomycin sensitizes cancer cells to the effects of doxorubicin and etoposide treatment by increasing DNA damage and reducing p21 proteinSalinomycin Suppresses PDGFRβ, MYC, and Notch Signaling in Human Medulloblastoma.Sequential Salinomycin Treatment Results in Resistance Formation through Clonal Selection of Epithelial-Like Tumor Cells.Translational phase I trial of vorinostat (suberoylanilide hydroxamic acid) combined with cytarabine and etoposide in patients with relapsed, refractory, or high-risk acute myeloid leukemiaSalinomycin enhances doxorubicin-induced cytotoxicity in multidrug resistant MCF-7/MDR human breast cancer cells via decreased efflux of doxorubicin.Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress.ROS-p53-cyclophilin-D signaling mediates salinomycin-induced glioma cell necrosisSalinomycin Promotes Anoikis and Decreases the CD44+/CD24- Stem-Like Population via Inhibition of STAT3 Activation in MDA-MB-231 CellsEnhanced expression of stem cell markers and drug resistance in sphere-forming non-small cell lung cancer cells.Breast cancer stem cell selectivity of synthetic nanomolar-active salinomycin analogsDrug Transporter-Mediated Protection of Cancer Stem Cells From Ionophore Antibiotics.Salinomycin exerts anti-angiogenic and anti-tumorigenic activities by inhibiting vascular endothelial growth factor receptor 2-mediated angiogenesis.Structure-Activity Relationships in Salinomycin: Cytotoxicity and Phenotype Selectivity of Semi-synthetic Derivatives.Lower salinomycin concentration increases apoptotic detachment in high-density cancer cells.Cancer stem cells and chemoresistance: The smartest survives the raidThe impact of metformin and salinomycin on transforming growth factor β-induced epithelial-to-mesenchymal transition in non-small cell lung cancer cell linesTherapeutic strategies targeting cancer stem cellsInhibition of the autophagic flux by salinomycin in breast cancer stem-like/progenitor cells interferes with their maintenanceSalinomycin induces cell death via inactivation of Stat3 and downregulation of Skp2.Salinomycin induces cell death with autophagy through activation of endoplasmic reticulum stress in human cancer cells.Combination of salinomycin and silver nanoparticles enhances apoptosis and autophagy in human ovarian cancer cells: an effective anticancer therapy.Low amount of salinomycin greatly increases Akt activation, but reduces activated p70S6K levelsAlantolactone selectively ablates acute myeloid leukemia stem and progenitor cells.The role of microRNAs in the regulation of cancer stem cells.Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases.NT1721, a novel epidithiodiketopiperazine, exhibits potent in vitro and in vivo efficacy against acute myeloid leukemia.Curcumin reduces the expression of survivin, leading to enhancement of arsenic trioxide-induced apoptosis in myelodysplastic syndrome and leukemia stem-like cells
P2860
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P2860
Salinomycin overcomes ABC transporter-mediated multidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cells.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Salinomycin overcomes ABC tran ...... ia stem cell-like KG-1a cells.
@ast
Salinomycin overcomes ABC tran ...... ia stem cell-like KG-1a cells.
@en
Salinomycin overcomes ABC tran ...... ia stem cell-like KG-1a cells.
@nl
type
label
Salinomycin overcomes ABC tran ...... ia stem cell-like KG-1a cells.
@ast
Salinomycin overcomes ABC tran ...... ia stem cell-like KG-1a cells.
@en
Salinomycin overcomes ABC tran ...... ia stem cell-like KG-1a cells.
@nl
prefLabel
Salinomycin overcomes ABC tran ...... ia stem cell-like KG-1a cells.
@ast
Salinomycin overcomes ABC tran ...... ia stem cell-like KG-1a cells.
@en
Salinomycin overcomes ABC tran ...... ia stem cell-like KG-1a cells.
@nl
P2093
P1476
Salinomycin overcomes ABC tran ...... ia stem cell-like KG-1a cells.
@en
P2093
Cord Naujokat
Dominik Fuchs
Mahmoud Sadeghi
Volker Daniel
P304
P356
10.1016/J.BBRC.2010.03.138
P407
P577
2010-03-27T00:00:00Z