Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway.
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MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin-mediated cell adhesion.Effect of cellular senescence on the albumin permeability of blood-derived endothelial cellsRap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functionsBypassing vasopressin receptor signaling pathways in nephrogenic diabetes insipidusRole of Rap1B and tumor suppressor PTEN in the negative regulation of lysophosphatidic acid--induced migration by isoproterenol in glioma cellsRole of EPAC in cAMP-Mediated Actions in Adrenocortical CellsBacillus anthracis edema factor substrate specificity: evidence for new modes of actionRole of guanine-nucleotide exchange factor Epac in renal physiology and pathophysiologySmall G proteins in the cardiovascular system: physiological and pathological aspectsRap1 can bypass the FAK-Src-Paxillin cascade to induce cell spreading and focal adhesion formationCell physiology of cAMP sensor Epac.Multiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functionsDiminution of signal transducer and activator of transcription 3 signaling inhibits vascular permeability and anaphylaxisNovel regulators of endothelial barrier functionActivation of GPR4 by acidosis increases endothelial cell adhesion through the cAMP/Epac pathwayEpac1 is upregulated during neointima formation and promotes vascular smooth muscle cell migrationRenal expression of exchange protein directly activated by cAMP (Epac) 1 and 2Urocortin induces positive inotropic effect in rat heartThe small GTPase Rap1 promotes cell movement rather than stabilizes adhesion in epithelial cells responding to insulin-like growth factor I.Recent advances in the discovery of small molecules targeting exchange proteins directly activated by cAMP (EPAC).Regulation of cellular communication by signaling microdomains in the blood vessel wall.The cAMP-responsive Rap1 guanine nucleotide exchange factor, Epac, induces smooth muscle relaxation by down-regulation of RhoA activity.Bacillus anthracis-derived edema toxin (ET) counter-regulates movement of neutrophils and macromolecules through the endothelial paracellular pathway.Cortactin deficiency is associated with reduced neutrophil recruitment but increased vascular permeability in vivoExchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells.Direct spatial control of Epac1 by cyclic AMP.Adherens junctions connect stress fibres between adjacent endothelial cellsPseudomonas aeruginosa exotoxin Y is a promiscuous cyclase that increases endothelial tau phosphorylation and permeabilityIloprost improves endothelial barrier function in lipopolysaccharide-induced lung injury.Whole-genome analysis of temporal gene expression during early transdifferentiation of human lung alveolar epithelial type 2 cells in vitroNovel pegylated interferon-β as strong suppressor of the malignant ascites in a peritoneal metastasis model of human cancer.Lung endothelial barrier protection by iloprost in the 2-hit models of ventilator-induced lung injury (VILI) involves inhibition of Rho signaling.Endothelial permeability is controlled by spatially defined cytoskeletal mechanics: atomic force microscopy force mapping of pulmonary endothelial monolayerVascular endothelial-cadherin stabilizes at cell-cell junctions by anchoring to circumferential actin bundles through alpha- and beta-catenins in cyclic AMP-Epac-Rap1 signal-activated endothelial cells.A Facile Method to Probe the Vascular Permeability of Nanoparticles in Nanomedicine Applications.Rac GTPase is a hub for protein kinase A and Epac signaling in endothelial barrier protection by cAMP.Endothelial permeability and VE-cadherin: a wacky comradeship.Control of cell adhesion dynamics by Rap1 signaling.Protective effect of Growth Hormone-Releasing Hormone agonist in bacterial toxin-induced pulmonary barrier dysfunction.Adenosine protected against pulmonary edema through transporter- and receptor A2-mediated endothelial barrier enhancement
P2860
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P2860
Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Cyclic AMP potentiates vascula ...... n Epac-Rap1 signaling pathway.
@ast
Cyclic AMP potentiates vascula ...... n Epac-Rap1 signaling pathway.
@en
Cyclic AMP potentiates vascula ...... n Epac-Rap1 signaling pathway.
@nl
type
label
Cyclic AMP potentiates vascula ...... n Epac-Rap1 signaling pathway.
@ast
Cyclic AMP potentiates vascula ...... n Epac-Rap1 signaling pathway.
@en
Cyclic AMP potentiates vascula ...... n Epac-Rap1 signaling pathway.
@nl
prefLabel
Cyclic AMP potentiates vascula ...... n Epac-Rap1 signaling pathway.
@ast
Cyclic AMP potentiates vascula ...... n Epac-Rap1 signaling pathway.
@en
Cyclic AMP potentiates vascula ...... n Epac-Rap1 signaling pathway.
@nl
P2093
P2860
P1476
Cyclic AMP potentiates vascula ...... n Epac-Rap1 signaling pathway.
@en
P2093
Akiko Yamagishi
Atsuko Sakurai
Hideto Sano
Kenji Kangawa
Naoki Mochizuki
Nobuyuki Takakura
Satoshi Somekawa
Shigetomo Fukuhara
Yoshihiko Saito
P2860
P304
P356
10.1128/MCB.25.1.136-146.2005
P407
P577
2005-01-01T00:00:00Z