Cloning of the human GLI2 Promoter: transcriptional activation by transforming growth factor-beta via SMAD3/beta-catenin cooperation. - Wikidata - wikimedia - TriplyDB

Cloning of the human GLI2 Promoter: transcriptional activation by transforming growth factor-beta via SMAD3/beta-catenin cooperation.

Cloning of the human GLI2 Promoter: transcriptional activation by transforming growth factor-beta via SMAD3/beta-catenin cooperation.

http://www.wikidata.org/entity/Q33553631

about

The hedgehog pathway in triple-negative breast cancer Signal Transduction Pathways of EMT Induced by TGF-β, SHH, and WNT and Their Crosstalks Non-Canonical Hh Signaling in Cancer-Current Understanding and Future Directions TGF-β/SMAD/GLI2 signaling axis in cancer progression and metastasis Context-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapy Cell density sensing alters TGF-β signaling in a cell-type-specific manner, independent from Hippo pathway activation Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer Constitutively active transforming growth factor β receptor 1 in the mouse ovary promotes tumorigenesis TGF-beta-RI kinase inhibitor SD-208 reduces the development and progression of melanoma bone metastases GLI2 regulates TGF-β1 in human CD4+ T cells: implications in cancer and HIV pathogenesis.Inhibition of hedgehog signaling decreases proliferation and clonogenicity of human mesenchymal stem cells.Targeting Hedgehog--a cancer stem cell pathway Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies.Molecular pathways and targets in prostate cancer Inflammation and Gli2 suppress gastrin gene expression in a murine model of antral hyperplasia Gli as a novel therapeutic target in malignant pleural mesothelioma Wnt signaling induces gene expression of factors associated with bone destruction in lung and breast cancer.Gli1 mediates lung cancer cell proliferation and Sonic Hedgehog-dependent mesenchymal cell activation.Targeting Gli transcription activation by small molecule suppresses tumor growth.TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling The hedgehog/Gli signaling paradigm in prostate cancer Minimal evidence for a direct involvement of twisted gastrulation homolog 1 (TWSG1) gene in human holoprosencephaly.The alpha subunit of the G protein G13 regulates activity of one or more Gli transcription factors independently of smoothened.Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells Methylation Microarray Studies Highlight PDGFA Expression as a Factor in Biliary Atresia Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis.Genome-wide search identifies a gene-gene interaction between 20p13 and 2q14 in asthma.2D difference gel electrophoresis analysis of different time points during the course of neoplastic transformation of human mammary epithelial cells.Role of glycogen synthase kinase-3β and PPAR-γ on epithelial-to-mesenchymal transition in DSS-induced colorectal fibrosis.Hedgehog signaling blockade delays hepatocarcinogenesis induced by hepatitis B virus X protein.MicroRNA Biogenesis and Hedgehog-Patched Signaling Cooperate to Regulate an Important Developmental Transition in Granule Cell Development.Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment.Protein kinase inhibitor SU6668 attenuates positive regulation of Gli proteins in cancer and multipotent progenitor cells.Hedgehog and TGFβ signaling converge on Gli2 to control bony invasion and bone destruction in oral squamous cell carcinoma Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells Molecular biology of pancreatic ductal adenocarcinoma progression: aberrant activation of developmental pathways.Hedgehog signaling in the liver.Hedgehog signalling in gut development, physiology and cancer.Crosstalk between TGF-β and hedgehog signaling in cancer.MITF, the Janus transcription factor of melanoma.

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P2860

Cloning of the human GLI2 Promoter: transcriptional activation by transforming growth factor-beta via SMAD3/beta-catenin cooperation.

http://www.wikidata.org/entity/Q33553631

description

2009 nî lūn-bûn

@nan

2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Cloning of the human GLI2 Prom ...... MAD3/beta-catenin cooperation.

@ast

Cloning of the human GLI2 Prom ...... MAD3/beta-catenin cooperation.

@en

Cloning of the human GLI2 Prom ...... MAD3/beta-catenin cooperation.

@nl

type

label

Cloning of the human GLI2 Prom ...... MAD3/beta-catenin cooperation.

@ast

Cloning of the human GLI2 Prom ...... MAD3/beta-catenin cooperation.

@en

Cloning of the human GLI2 Prom ...... MAD3/beta-catenin cooperation.

@nl

prefLabel

Cloning of the human GLI2 Prom ...... MAD3/beta-catenin cooperation.

@ast

Cloning of the human GLI2 Prom ...... MAD3/beta-catenin cooperation.

@en

Cloning of the human GLI2 Prom ...... MAD3/beta-catenin cooperation.

@nl

P1433

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P356

JBC.M109.059964

P1433

Journal of Biological Chemistry

P1476

Cloning of the human GLI2 Prom ...... MAD3/beta-catenin cooperation.

@en

P2093

Alain Mauviel

http://www.w3.org/2001/XMLSchema#string

Jocelyne André

http://www.w3.org/2001/XMLSchema#string

Sylviane Dennler

http://www.w3.org/2001/XMLSchema#string

P2860

A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2

Interaction between Smad7 and beta-catenin: importance for transforming growth factor beta-induced apoptosis

Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways

Identification of the LIM protein FHL2 as a coactivator of beta-catenin

Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo

New insights into TGF-beta-Smad signalling

Smad transcription factors

TGFbeta in Cancer

Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene.

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31523-31531

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scholarly article

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10.1074/JBC.M109.059964

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P433

46

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P478

284

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Franck Verrecchia

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2009-09-21T00:00:00Z

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19797115

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2797221

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