RAG2's acidic hinge restricts repair-pathway choice and promotes genomic stability.
about
Relating sequence encoded information to form and function of intrinsically disordered proteinsRAG2 mutants alter DSB repair pathway choice in vivo and illuminate the nature of 'alternative NHEJ'.An autoregulatory mechanism imposes allosteric control on the V(D)J recombinase by histone H3 methylation.RAG2 and XLF/Cernunnos interplay reveals a novel role for the RAG complex in DNA repairRestoration of ATM Expression in DNA-PKcs-Deficient Cells Inhibits Signal End Joining.V(D)J Recombination: Mechanism, Errors, and Fidelity.Riches in RAGs: Revealing the V(D)J Recombinase through High-Resolution Structures.The ATM Kinase Restrains Joining of Both VDJ Signal and Coding Ends.Disruption of the RAG2 zinc finger motif impairs protein stability and causes immunodeficiency.RAG1/2 induces genomic insertions by mobilizing DNA into RAG1/2-independent breaksThe Conserved ATM Kinase RAG2-S365 Phosphorylation Site Limits Cleavage Events in Individual Cells Independent of Any Repair Defect.
P2860
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P2860
RAG2's acidic hinge restricts repair-pathway choice and promotes genomic stability.
description
2013 nî lūn-bûn
@nan
2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
RAG2's acidic hinge restricts repair-pathway choice and promotes genomic stability.
@ast
RAG2's acidic hinge restricts repair-pathway choice and promotes genomic stability.
@en
RAG2's acidic hinge restricts repair-pathway choice and promotes genomic stability.
@nl
type
label
RAG2's acidic hinge restricts repair-pathway choice and promotes genomic stability.
@ast
RAG2's acidic hinge restricts repair-pathway choice and promotes genomic stability.
@en
RAG2's acidic hinge restricts repair-pathway choice and promotes genomic stability.
@nl
prefLabel
RAG2's acidic hinge restricts repair-pathway choice and promotes genomic stability.
@ast
RAG2's acidic hinge restricts repair-pathway choice and promotes genomic stability.
@en
RAG2's acidic hinge restricts repair-pathway choice and promotes genomic stability.
@nl
P2093
P2860
P1433
P1476
RAG2's acidic hinge restricts repair-pathway choice and promotes genomic stability.
@en
P2093
Cory R Lindsay
David B Roth
Marc A Coussens
Rebecca L Wendland
Suzzette M Arnal
P2860
P304
P356
10.1016/J.CELREP.2013.07.041
P577
2013-08-29T00:00:00Z