Impairment of developmental stem cell-mediated striatal neurogenesis and pluripotency genes in a knock-in model of Huntington's disease - Wikidata - wikimedia - TriplyDB

Impairment of developmental stem cell-mediated striatal neurogenesis and pluripotency genes in a knock-in model of Huntington's disease

Impairment of developmental stem cell-mediated striatal neurogenesis and pluripotency genes in a knock-in model of Huntington's disease

http://www.wikidata.org/entity/Q33564443

about

Mind the gap: models in multiple species needed for therapeutic development in Huntington's disease Modeling Huntington's disease with induced pluripotent stem cells Epigenetics and therapeutic targets mediating neuroprotection A broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington's disease CAG knock-in mice.Huntingtin Is Required for Neural But Not Cardiac/Pancreatic Progenitor Differentiation of Mouse Embryonic Stem Cells In vitro.Multiple phenotypes in Huntington disease mouse neural stem cells.Anaesthetics-induced neurotoxicity in developing brain: an update on preclinical evidence.Corepressor for element-1-silencing transcription factor preferentially mediates gene networks underlying neural stem cell fate decisions.Cerebral cortex structure in prodromal Huntington disease.Smaller intracranial volume in prodromal Huntington's disease: evidence for abnormal neurodevelopment.REST and CoREST are transcriptional and epigenetic regulators of seminal neural fate decisions.Selective roles of normal and mutant huntingtin in neural induction and early neurogenesis Functions of huntingtin in germ layer specification and organogenesis.Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis.Phenotyping dividing cells in mouse models of neurodegenerative basal ganglia diseases.Correlation of CAG repeat length between the maternal and paternal allele of the Huntingtin gene: evidence for assortative mating.HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity.Homeobox genes in obsessive-compulsive disorder.Huntington disease iPSCs show early molecular changes in intracellular signaling, the expression of oxidative stress proteins and the p53 pathway Measures of growth in children at risk for Huntington disease Huntington's Disease as Neurodevelopmental Disorder: Altered Chromatin Regulation, Coding, and Non-Coding RNA Transcription.Extensive changes in DNA methylation are associated with expression of mutant huntingtin.Selective expression of mutant huntingtin during development recapitulates characteristic features of Huntington's disease Molecular mechanisms and potential therapeutical targets in Huntington's disease.The multiplicity of action of cannabinoids: implications for treating neurodegeneration.Huntington's disease: can mice lead the way to treatment?Utilization of neural stem cell-derived models to study anesthesia-related toxicity and preventative approaches.The influence of cannabinoids on generic traits of neurodegeneration.Huntington Disease as a Neurodevelopmental Disorder and Early Signs of the Disease in Stem Cells.Genomic Analysis Reveals Disruption of Striatal Neuronal Development and Therapeutic Targets in Human Huntington's Disease Neural Stem Cells.Long Term Aggresome Accumulation Leads to DNA Damage, p53-dependent Cell Cycle Arrest, and Steric Interference in Mitosis.Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice.Similar Progression of Morphological and Metabolic Phenotype in R6/2 Mice with Different CAG Repeats Revealed by In Vivo Magnetic Resonance Imaging and Spectroscopy.Cholinergic interneurons in the Q140 knockin mouse model of Huntington's disease: Reductions in dendritic branching and thalamostriatal input.The Generation of Mouse and Human Huntington Disease iPS Cells Suitable for In vitro Studies on Huntingtin Function Hedgehog controls neural stem cells through p53-independent regulation of Nanog.Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeat-expansion-associated phenotypes.Adult neural progenitor cells from Huntington's disease mouse brain exhibit increased proliferation and migration due to enhanced calcium and ROS signals.Postnatal and adult consequences of loss of huntingtin during development: Implications for Huntington's disease.Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition

P2860

Q26827496-2AB45EAA-2F31-4BBB-9CF2-DC094FAF783A Q27004209-D6BDC7BF-17A0-4AA7-83C9-7FEE7FDBCA28 Q28080633-A05FCFF0-5CCE-441E-9300-8C874AFF1A28 Q28391627-C5F9C56D-1E9A-445F-8146-2DF3E9B7F3EC Q30353778-DDE4C2C8-A2E9-4169-AF32-17DB5DB75E5F Q30419653-6029072A-7761-4A99-B783-048337391255 Q33788924-61B1E390-83F6-4FC5-82B8-758CADC7250A Q34151845-1A74E6D8-DB14-4C43-A2DC-FD31C0CC23D6 Q34204077-9521564B-1CED-4710-817D-F1C052445866 Q34514619-209D9424-A756-4B63-80A3-2989CD189E36 Q34620878-C5793473-0131-4DC7-82EF-8187E3B35628 Q34731481-EC8ADCFF-AE4B-4EBA-9127-C3A94840E34B Q34965525-69D41AE6-43A2-4414-B740-70C4E61865F7 Q34994813-7CF3A7C1-FD9B-40F5-B855-74692514960A Q35007247-C8136F79-8FF4-4FE1-9423-DC56A55F4A8E Q35560130-5E0E22B9-96E9-4E75-BED6-D9CDFE0C38BD Q35585297-B0233539-D20B-4F85-87A6-07D809A3D2B0 Q35647889-0B20EE6D-3CC2-423C-B143-539745CF6887 Q36090810-AB1B17DA-011A-4303-A0DD-0C3F8A8B5569 Q36149988-6BDA6240-9764-4239-9396-B232CCFE4B03 Q36456618-EA1F88F2-297C-4D1F-8311-30D98E1AB9AF Q36598186-5F63872E-7919-435E-8C94-A8B64F6DF1FF Q36931043-308F8F62-9E1C-4A6F-AB61-295B392724AC Q37776087-FE91C2F8-8E8B-4B04-85CC-E59C3CC3F300 Q37793366-6DF3E1AE-54C9-4BB1-BB8D-53A0DD0D8449 Q37840353-89710FC1-2540-4E6C-9098-7B02C2DFF4AB Q38120959-B7B96BE2-8BB8-4EEB-8DE7-1847100539D3 Q38156518-0CDDC537-B5B6-46E0-B4E7-55BFD832E0EA Q38790183-1A7395F4-742B-4A3F-9D45-4211E1021F96 Q38813105-715CAE95-2FB1-4E8E-BE9B-70E398B6BDDE Q38832369-B3221CC9-8625-4D52-833B-7705920A6236 Q38893465-B986415E-827E-4D47-92BB-861EC7868E6D Q39357699-87A4A123-8C36-4E4A-B09F-C67742ABC55F Q39740166-07F8DFB2-0A48-4A35-8D15-35E76F1D4ED6 Q41334055-B9FEA4A6-452B-46A3-B8BA-05559F1C8C20 Q42474956-5FB7D6C9-DEF9-454D-B1DB-3999D0D023C2 Q42714345-411137F1-9EAA-4082-9232-8408EBB4E21D Q45289522-7DC71626-D227-48B2-B89C-99E8C5719E96 Q45297446-952CB09B-8CAE-47C4-BD44-A922DB7FCA32 Q58700269-9F9E53BE-07AE-40F1-9A2C-8B51E9366283

P2860

Impairment of developmental stem cell-mediated striatal neurogenesis and pluripotency genes in a knock-in model of Huntington's disease

http://www.wikidata.org/entity/Q33564443

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Impairment of developmental st ...... model of Huntington's disease

@ast

Impairment of developmental st ...... model of Huntington's disease

@en

Impairment of developmental st ...... model of Huntington's disease.

@nl

type

label

Impairment of developmental st ...... model of Huntington's disease

@ast

Impairment of developmental st ...... model of Huntington's disease

@en

Impairment of developmental st ...... model of Huntington's disease.

@nl

prefLabel

Impairment of developmental st ...... model of Huntington's disease

@ast

Impairment of developmental st ...... model of Huntington's disease

@en

Impairment of developmental st ...... model of Huntington's disease.

@nl

P1433

Q33564443-3DC534C2-3742-42F5-BBC9-BD9695A3F30D

P1476

Q33564443-86F2D765-250B-4171-AF73-BCD07A4F9498

P2093

Q33564443-13448CE8-DE5F-45E8-BA9D-FD0AEDE1C0B4

Q33564443-2BA8E815-B29D-4089-BB80-84D141DE95E9

Q33564443-387B460E-D63B-4B60-B26B-93673BF12CF3

Q33564443-CA42C7B0-6875-42A6-8866-6527E0DB748B

Q33564443-CBA359F2-33D6-437A-A624-7F2A61FD3B7A

P2860

Q33564443-0730481D-CFCF-4641-BC64-71477AA1FB63

Q33564443-0757E92B-56F5-4A0A-915A-0A50520BBE6F

Q33564443-0B2E7D5E-20BC-4980-9B1A-C36976D59C45

Q33564443-0DE3AFE2-FABF-4807-BC42-37C3038AB296

Q33564443-14DD1D56-0CBC-415B-B044-7AFC0F7BD0FE

Q33564443-1D636E58-826F-45D7-A70A-BED9DBB32D58

Q33564443-35D0C2DE-D3C9-40C7-9835-5BE2144F0425

Q33564443-40AB7718-09CC-4B3A-8A38-1073CA0BBDC6

Q33564443-41388F35-6497-4027-BC3C-EA893CD44220

Q33564443-4368B0B8-BC04-4650-90CD-7C72683F1EA9

P304

Q33564443-474E8EEC-922C-4623-8658-B0E98F9262A5

P31

Q33564443-F99DCB42-289F-44F7-82EF-4F4DD8521671

P356

Q33564443-3DC97220-6583-4CF0-9A03-58C84596F1EE

P407

Q33564443-08EB8A7E-EF44-4084-A3E0-4991B3AB4859

P433

Q33564443-AAA684FA-4308-4BC1-A083-9A494476C01B

P478

Q33564443-F7E234D0-0F69-43CE-9599-9701F9097BC5

P50

Q33564443-61A4D6C5-8240-449B-A982-0E7FFB43C1D2

P577

Q33564443-8884433B-3BC3-447C-B585-2DE73A8569CC

P5875

Q33564443-50E3F8DB-09FB-439E-AF0D-2A153BCE8E53

P698

Q33564443-9CB69EEE-AE8D-4A05-8793-DB396FAE2187

P921

Q33564443-5D5EB6E7-F67B-434F-91A4-986231BB672A

Q33564443-8ABA02E2-7D1F-4C31-A0B5-4BE8302980CC

P932

Q33564443-ED46D29D-7690-4995-9C7F-5ECE099597F9

P356

PNAS.0912171106

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Impairment of developmental st ...... model of Huntington's disease

@en

P2093

Jessica L Feig

http://www.w3.org/2001/XMLSchema#string

Lucien C Alexandre

http://www.w3.org/2001/XMLSchema#string

Mark F Mehler

http://www.w3.org/2001/XMLSchema#string

Sara Gonzalez

http://www.w3.org/2001/XMLSchema#string

Solen Gokhan

http://www.w3.org/2001/XMLSchema#string

P2860

The transcriptional foundation of pluripotency

In vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampus

Inactivation of the Huntington's disease gene (Hdh) impairs anterior streak formation and early patterning of the mouse embryo.

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

Ephrin-A binding and EphA receptor expression delineate the matrix compartment of the striatum

The homeodomain protein Nanog and pluripotency in mouse embryonic stem cells

Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain

Neurons lacking huntingtin differentially colonize brain and survive in chimeric mice

Impaired learning-dependent cortical plasticity in Huntington's disease transgenic mice

Notch signaling coordinates the patterning of striatal compartments

P304

21900-21905

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0912171106

http://www.w3.org/2001/XMLSchema#string

P407

P433

51

http://www.w3.org/2001/XMLSchema#string

P478

106

http://www.w3.org/2001/XMLSchema#string

P50

Aldrin E Molero

P577

2009-12-02T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

40442568

http://www.w3.org/2001/XMLSchema#string

P698

19955426

http://www.w3.org/2001/XMLSchema#string

P921

corpus striatum

Huntington disease

P932

2799796

http://www.w3.org/2001/XMLSchema#string