A novel approach using DNA-repair-deficient chicken DT40 cell lines for screening and characterizing the genotoxicity of environmental contaminants.
about
Application of toxicogenomic profiling to evaluate effects of benzene and formaldehyde: from yeast to humanCollaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repairThe dominant role of proofreading exonuclease activity of replicative polymerase ε in cellular tolerance to cytarabine (Ara-C)The epistatic relationship between BRCA2 and the other RAD51 mediators in homologous recombination.Genetic toxicology in the 21st century: reflections and future directions.Identification of genotoxic compounds using isogenic DNA repair deficient DT40 cell lines on a quantitative high throughput screening platform.Characterization of environmental chemicals with potential for DNA damage using isogenic DNA repair-deficient chicken DT40 cell lines.Evaluating the effects of bioremediation on genotoxicity of polycyclic aromatic hydrocarbon-contaminated soil using genetically engineered, higher eukaryotic cell linesCell-based high-throughput screens for the discovery of chemotherapeutic agents.Aerobic Bioremediation of PAH Contaminated Soil Results in Increased Genotoxicity and Developmental Toxicity.Isotonic Regression Based-Method in Quantitative High-Throughput Screenings for Genotoxicity.Incorporation of metabolic activation potentiates cyclophosphamide-induced DNA damage response in isogenic DT40 mutant cellsEmerging approaches in predictive toxicology.Differential and common DNA repair pathways for topoisomerase I- and II-targeted drugs in a genetic DT40 repair cell screen panel.Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells.Convenient, multi-well plate-based DNA damage response analysis using DT40 mutants is applicable to a high-throughput genotoxicity assay with characterization of modes of action.Editor's Highlight: High-Throughput Functional Genomics Identifies Modulators of TCE Metabolite Genotoxicity and Candidate Susceptibility Genes.Assessment of the DNA damaging potential of environmental chemicals using a quantitative high-throughput screening approach to measure p53 activation.
P2860
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P2860
A novel approach using DNA-repair-deficient chicken DT40 cell lines for screening and characterizing the genotoxicity of environmental contaminants.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
A novel approach using DNA-rep ...... of environmental contaminants.
@ast
A novel approach using DNA-rep ...... of environmental contaminants.
@en
A novel approach using DNA-rep ...... of environmental contaminants.
@nl
type
label
A novel approach using DNA-rep ...... of environmental contaminants.
@ast
A novel approach using DNA-rep ...... of environmental contaminants.
@en
A novel approach using DNA-rep ...... of environmental contaminants.
@nl
prefLabel
A novel approach using DNA-rep ...... of environmental contaminants.
@ast
A novel approach using DNA-rep ...... of environmental contaminants.
@en
A novel approach using DNA-rep ...... of environmental contaminants.
@nl
P2093
P2860
P356
P1476
A novel approach using DNA-rep ...... of environmental contaminants.
@en
P2093
Jinyoung Lee
Kyunghee Ji
Toshiaki Kogame
Yoshihito Taniguchi
P2860
P304
P356
10.1289/EHP.0900842
P577
2009-06-26T00:00:00Z