The epistatic relationship between BRCA2 and the other RAD51 mediators in homologous recombination. - Wikidata - wikimedia - TriplyDB

The epistatic relationship between BRCA2 and the other RAD51 mediators in homologous recombination.

The epistatic relationship between BRCA2 and the other RAD51 mediators in homologous recombination.

http://www.wikidata.org/entity/Q33967965

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BRCA1 and CtIP Are Both Required to Recruit Dna2 at Double-Strand Breaks in Homologous Recombination Relative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double-strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell lines RAD52 inactivation is synthetically lethal with deficiencies in BRCA1 and PALB2 in addition to BRCA2 through RAD51-mediated homologous recombination The logic and mechanism of homologous recombination partner choice The dominant role of proofreading exonuclease activity of replicative polymerase ε in cellular tolerance to cytarabine (Ara-C)Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents Epistatic relationships in the BRCA1-BRCA2 pathway Histone modifications and DNA double-strand break repair after exposure to ionizing radiations.Molecular pathways: understanding the role of Rad52 in homologous recombination for therapeutic advancement.Combined optical and topographic imaging reveals different arrangements of human RAD54 with presynaptic and postsynaptic RAD51-DNA filaments Cell biology of mitotic recombination.Smarcal1 promotes double-strand-break repair by nonhomologous end-joining.Plk1 and CK2 act in concert to regulate Rad51 during DNA double strand break repair.Genetic Evidence for Genotoxic Effect of Entecavir, an Anti-Hepatitis B Virus Nucleotide Analog.Inherited variation at chromosome 12p13.33, including RAD52, influences the risk of squamous cell lung carcinoma.Chromatin modifications and the DNA damage response to ionizing radiation.Suppression of Jab1/CSN5 induces radio- and chemo-sensitivity in nasopharyngeal carcinoma through changes to the DNA damage and repair pathways Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart.Inhibition of BRCA2 and Thymidylate Synthase Creates Multidrug Sensitive Tumor Cells via the Induction of Combined "Complementary Lethality".Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions.Shu1 promotes homolog bias of meiotic recombination in Saccharomyces cerevisiae.Epigenetic regulation of genomic integrity.DNA double-strand break repair as determinant of cellular radiosensitivity to killing and target in radiation therapy.Targeting homologous recombination-mediated DNA repair in cancer.Mediators of homologous DNA pairing.Recombinational branch migration by the RadA/Sms paralog of RecA in Escherichia coli.The Shu complex is a conserved regulator of homologous recombination.High levels of BRC4 induced by a Tet-On 3G system suppress DNA repair and impair cell proliferation in vertebrate cells.SUMO-targeted ubiquitin ligase RNF4 plays a critical role in preventing chromosome loss.Tipin functions in the protection against topoisomerase I inhibitor ATM- and ATR-mediated phosphorylation of XRCC3 regulates DNA double-strand break-induced checkpoint activation and repair.BRCA2 is epistatic to the RAD51 paralogs in response to DNA damage BRCA1 promotes unloading of the CMG helicase from a stalled DNA replication fork Effects of XRCC2 and RAD51B mutations on somatic and meiotic recombination in Arabidopsis thaliana.Editor's Highlight: High-Throughput Functional Genomics Identifies Modulators of TCE Metabolite Genotoxicity and Candidate Susceptibility Genes.Main steps in DNA double-strand break repair: an introduction to homologous recombination and related processes.Overexpression of BLM promotes DNA damage and increased sensitivity to platinum salts in triple negative breast and serous ovarian cancers.The functional status of DNA repair pathways determines the sensitization effect to cisplatin in non-small cell lung cancer cells.

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The epistatic relationship between BRCA2 and the other RAD51 mediators in homologous recombination.

http://www.wikidata.org/entity/Q33967965

description

2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

The epistatic relationship bet ...... s in homologous recombination.

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The epistatic relationship bet ...... s in homologous recombination.

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The epistatic relationship bet ...... s in homologous recombination.

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The epistatic relationship bet ...... s in homologous recombination.

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The epistatic relationship bet ...... s in homologous recombination.

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The epistatic relationship bet ...... s in homologous recombination.

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The epistatic relationship bet ...... s in homologous recombination.

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Douglas K Bishop

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Kimiyo N Yamamoto

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Kouji Hirota

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Mitsuyoshi Yamazoe

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Wataru Sakai

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XiaoHua Wu

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Yong Qing

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P2860

BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair

Purified human BRCA2 stimulates RAD51-mediated recombination

A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination

PALB2 is an integral component of the BRCA complex required for homologous recombination repair

The BRC repeats of BRCA2 modulate the DNA-binding selectivity of RAD51

Sws1 is a conserved regulator of homologous recombination in eukaryotic cells

Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae

The Rad51 paralog Rad51B promotes homologous recombinational repair

Susceptibility pathways in Fanconi's anemia and breast cancer

Human CtIP promotes DNA end resection

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7

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7

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Donniphat Dejsuphong

Shunichi Takeda

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2011-07-14T00:00:00Z

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51511608

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