Structural typing of systemic amyloidoses by luminescent-conjugated polymer spectroscopy.
about
Insulin-like growth factor II mRNA binding protein 3 (IMP3) is overexpressed in prostate cancer and correlates with higher Gleason scores.Drosophila melanogaster as a model system for studies of islet amyloid polypeptide aggregation.Synthesis of a library of oligothiophenes and their utilization as fluorescent ligands for spectral assignment of protein aggregates.Prion strain interactions are highly selective.The structural basis for optimal performance of oligothiophene-based fluorescent amyloid ligands: conformational flexibility is essential for spectral assignment of a diversity of protein aggregates.Lymphotoxin, but not TNF, is required for prion invasion of lymph nodes.Sensitive and rapid assessment of amyloid by oligothiophene fluorescence in subcutaneous fat tissue.Distinct Spacing Between Anionic Groups: An Essential Chemical Determinant for Achieving Thiophene-Based Ligands to Distinguish β-Amyloid or Tau Polymorphic AggregatesStructure-based drug design identifies polythiophenes as antiprion compounds.Insight into amyloid structure using chemical probes.Targeting class IA PI3K isoforms selectively impairs cell growth, survival, and migration in glioblastoma.Tracking protein aggregate interactions.Spongiform encephalopathy in transgenic mice expressing a point mutation in the β2-α2 loop of the prion protein.Polythiophenes inhibit prion propagation by stabilizing prion protein (PrP) aggregates.Processing of nerve biopsies: a practical guide for neuropathologists.Luminescent conjugated poly- and oligo-thiophenes: optical ligands for spectral assignment of a plethora of protein aggregates.Nuclear inclusion bodies of mutant and wild-type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodelling by p53 aggregation.Pathological, biochemical, and biophysical characteristics of the transthyretin variant Y114H (p.Y134H) explain its very mild clinical phenotype.Luminescent conjugated oligothiophenes for sensitive fluorescent assignment of protein inclusion bodiesMultimodal fluorescence microscopy of prion strain specific PrP deposits stained by thiophene-based amyloid ligands.Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice.Enhanced fluorescent assignment of protein aggregates by an oligothiophene-porphyrin-based amyloid ligand.Therapeutic strategies to prevent Alzheimer's disease pathogenesis using a fluorescent conjugated polyelectrolyte.PTAA and B10: new approaches to amyloid detection in tissue-evaluation of amyloid detection in tissue with a conjugated polyelectrolyte and a fibril-specific antibody fragment.An Environmentally Sensitive Fluorescent Dye as a Multidimensional Probe of Amyloid Formation.Amyloid fibril polymorphism - a challenge for molecular imaging and therapy.Establishing the fluorescent amyloid ligand h-FTAA for studying human tissues with systemic and localized amyloid.Protein Aggregation in Neurodegeneration
P2860
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P2860
Structural typing of systemic amyloidoses by luminescent-conjugated polymer spectroscopy.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structural typing of systemic amyloidoses by luminescent-conjugated polymer spectroscopy.
@ast
Structural typing of systemic amyloidoses by luminescent-conjugated polymer spectroscopy.
@en
type
label
Structural typing of systemic amyloidoses by luminescent-conjugated polymer spectroscopy.
@ast
Structural typing of systemic amyloidoses by luminescent-conjugated polymer spectroscopy.
@en
prefLabel
Structural typing of systemic amyloidoses by luminescent-conjugated polymer spectroscopy.
@ast
Structural typing of systemic amyloidoses by luminescent-conjugated polymer spectroscopy.
@en
P2093
P2860
P50
P1476
Structural typing of systemic amyloidoses by luminescent-conjugated polymer spectroscopy.
@en
P2093
Andreas Aslund
Holger Moch
K Peter R Nilsson
Peter Konradsson
Sophia Fransson
P2860
P304
P356
10.2353/AJPATH.2010.080797
P407
P577
2009-12-24T00:00:00Z