sameAs
Aerosols transmit prions to immunocompetent and immunodeficient miceEmbryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1.Deregulated expression of PAX5 in medulloblastomaFollicular dendritic cells control engulfment of apoptotic bodies by secreting Mfge8Unraveling prion strains with cell biology and organic chemistryAnalysis of prion strains by PrPSc profiling in sporadic Creutzfeldt-Jakob disease.New and emerging roles of small RNAs in neurodegeneration, muscle, cardiovascular and inflammatory diseasesZyFISH: a simple, rapid and reliable zygosity assay for transgenic miceThe strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of diseaseNeurodegeneration and unfolded-protein response in mice expressing a membrane-tethered flexible tail of PrPPrion pathogenesis in the absence of NLRP3/ASC inflammasomesA matrix-less measles virus is infectious and elicits extensive cell fusion: consequences for propagation in the brain.The amyloid-Congo red interface at atomic resolutionThe crystal structure of an octapeptide repeat of the Prion protein in complex with a Fab fragment of the POM2 antibodyStructural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1The toxicity of antiprion antibodies is mediated by the flexible tail of the prion proteinStructural basis of prion inhibition by phenothiazine compoundsX-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteinsAdenoviral and adeno-associated viral transfer of genes to the peripheral nervous systemImpaired prion replication in spleens of mice lacking functional follicular dendritic cellsThe adaptor ASC has extracellular and 'prionoid' activities that propagate inflammationMice devoid of PrP are resistant to scrapieThe prion gene is associated with human long-term memoryThe prion's elusive reason for beingCharacterizing follicular dendritic cells: A progress reportBenzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptorsPreclinical deposition of pathological prion protein in muscle of experimentally infected primatesEssential role for the c-met receptor in the migration of myogenic precursor cells into the limb budAn essential function for NBS1 in the prevention of ataxia and cerebellar defectsAblation of Dicer from murine Schwann cells increases their proliferation while blocking myelinationThe lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn miceThe prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6The AP-1 transcription factor c-Jun is required for efficient axonal regenerationThe Priority position paper: Protecting Europe's food chain from prionsGlobular domain of the prion protein needs to be unlocked by domain swapping to support prion protein conversionLethal recessive myelin toxicity of prion protein lacking its central domain.Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease.De novo generation of a transmissible spongiform encephalopathy by mouse transgenesisMicroglial ablation and lipopolysaccharide preconditioning affects pilocarpine-induced seizures in mice.Novel dominant-negative prion protein mutants identified from a randomized library.
P50
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P50
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Swiss physician
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Swiss physician
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Swiss physician
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auteur uit Zwitserland
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dochtúir Eilvéiseach
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italienisch-schweizerischer Mediziner
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medic elvețian
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metge suís
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mjek zviceran
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Adriano Aguzzi
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Adriano Aguzzi
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Adriano Aguzzi
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Adriano Aguzzi
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Adriano Aguzzi
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Adriano Aguzzi
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Adriano Aguzzi
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Adriano Aguzzi
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Adriano Aguzzi
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Adriano Aguzzi
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Adriano Aguzzi
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Adriano Aguzzi
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Adriano Aguzzi
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Adriano Aguzzi
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Adriano Aguzzi
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Adriano Aguzzi
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