GPR120 (FFAR4) is preferentially expressed in pancreatic delta cells and regulates somatostatin secretion from murine islets of Langerhans.
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The L-Cell in Nutritional Sensing and the Regulation of AppetiteOmega-3 Fatty Acids and FFAR4The beneficial effects of n-3 polyunsaturated fatty acids on diet induced obesity and impaired glucose control do not require Gpr120.The ethyl acetate fraction of corn silk exhibits dual antioxidant and anti-glycation activities and protects insulin-secreting cells from glucotoxicity.Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitectureGLUT4 Expression in Adipocytes Regulates De Novo Lipogenesis and Levels of a Novel Class of Lipids With Antidiabetic and Anti-inflammatory Effects.A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure.Regulation of Energy Homeostasis via GPR120.Characterizing pharmacological ligands to study the long-chain fatty acid receptors GPR40/FFA1 and GPR120/FFA4.Treatment of type 2 diabetes by free Fatty Acid receptor agonists.Biological characteristics and agonists of GPR120 (FFAR4) receptor: the present status of research.G protein-coupled receptors as new therapeutic targets for type 2 diabetes.G protein-coupled receptors: signalling and regulation by lipid agonists for improved glucose homoeostasis.Fatty acid and mineral receptors as drug targets for gastrointestinal disorders.Polymorphic Variation in FFA Receptors: Functions and Consequences.Gut Hormone Regulation and Secretion via FFA1 and FFA4.A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice.FFA4/GPR120: Pharmacology and Therapeutic Opportunities.Targeted Elimination of G Proteins and Arrestins Defines Their Specific Contributions to Both Intensity and Duration of G Protein-coupled Receptor Signaling.Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population.Design, Synthesis, and Evaluation of Novel and Selective G-protein Coupled Receptor 120 (GPR120) Spirocyclic Agonists.The acute glucose lowering effect of specific GPR120 activation in mice is mainly driven by glucagon-like peptide 1.Polymorphisms in FFAR4 (GPR120) Gene Modulate Insulin Levels and Sensitivity after Fish Oil Supplementation.Agonism of free fatty acid receptors 1 and 4 generates peptide YY-mediated inhibitory responses in mouse colon.The role of free-fatty acid receptor-4 (FFA4) in human cancers and cancer cell lines.Discovery of Chromane Propionic Acid Analogues as Selective Agonists of GPR120 with in Vivo Activity in Rodents.Pharmacological Tool Compounds for the Free Fatty Acid Receptor 4 (FFA4/GPR120).Distinct Phosphorylation Clusters Determine the Signaling Outcome of Free Fatty Acid Receptor 4/G Protein-Coupled Receptor 120.Activity of dietary fatty acids on FFA1 and FFA4 and characterisation of pinolenic acid as a dual FFA1/FFA4 agonist with potential effect against metabolic diseasesDissecting the Physiology and Pathophysiology of Glucagon-Like Peptide-1
P2860
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P2860
GPR120 (FFAR4) is preferentially expressed in pancreatic delta cells and regulates somatostatin secretion from murine islets of Langerhans.
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
GPR120 (FFAR4) is preferential ...... m murine islets of Langerhans.
@ast
GPR120 (FFAR4) is preferential ...... m murine islets of Langerhans.
@en
type
label
GPR120 (FFAR4) is preferential ...... m murine islets of Langerhans.
@ast
GPR120 (FFAR4) is preferential ...... m murine islets of Langerhans.
@en
prefLabel
GPR120 (FFAR4) is preferential ...... m murine islets of Langerhans.
@ast
GPR120 (FFAR4) is preferential ...... m murine islets of Langerhans.
@en
P2093
P2860
P1433
P1476
GPR120 (FFAR4) is preferential ...... m murine islets of Langerhans.
@en
P2093
Carol Lenaghan
David M Smith
Katy J Brocklehurst
Maria Sörhede Winzell
Mårten Hammar
Shalinee Dhayal
Virginia M Stone
Xiufeng Xu
P2860
P2888
P304
P356
10.1007/S00125-014-3213-0
P577
2014-03-25T00:00:00Z
P5875
P6179
1025783957